A5010748276- Dialysis and Renal Disease Management
- Central Venous Catheters and Hemodialysis
- Muscle and Compartmental Disorders
- Chronic Kidney Disease and Diabetes
- Parathyroid Disorders and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Iron Metabolism and Disorders
- Renal Transplantation Outcomes and Treatments
- Healthcare cost, quality, practices
- Hepatitis C virus research
- Organ Donation and Transplantation
- Liver Disease Diagnosis and Treatment
- Pharmacological Effects and Toxicity Studies
- Neurological and metabolic disorders
- Acute Kidney Injury Research
- Metabolism and Genetic Disorders
- Pancreatitis Pathology and Treatment
- Organ Transplantation Techniques and Outcomes
- Renal and Vascular Pathologies
- Hepatitis B Virus Studies
- Heart Failure Treatment and Management
- Nosocomial Infections in ICU
- Neurological Complications and Syndromes
- Erythropoietin and Anemia Treatment
- Potassium and Related Disorders
Hospital de Santo António
2016-2025
Universidade do Porto
2013-2024
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2024
CUF Porto Hospital
2023
University of Coimbra
2023
Centro Hospitalar do Porto
2012-2022
Hospital de São Bernardo
2021
IPO Porto
2019
Universidad de la República
2017
Institute of Biomedical Science
2011-2016
Infections are major complications in peritoneal dialysis (PD) with a multifactorial etiology that comprises patient, microbial and dialytic factors. This study aimed at investigating the contribution of biofilms on PD catheters to recalcitrant infections their interplay related-factors. A prospective observational was performed 47 patients attending Centro Hospitalar Porto Vila Nova de Gaia/Espinho whom catheter removed due infectious (n = 16) non-infectious causes 31). Microbial density...
O presente artigo visa elucidar as questões que estão contidas na legislação de drogas introduzida no ordenamento jurídico brasileiro ano 2006, acabou por começar a diferenciar condutas dos indivíduos tange à posse e traficância, especificando uma penalidade para cada tipo crime, tanto, levando em conta sua gravidade. Ainda nesse contexto, o estudo bibliográfico aqui realizado aspira contextualizar posição da mídia frente problemática das país, tanto estigmatização do usuário droga como...
<i>Background/Aim:</i> The determinants of baseline fast solute transport are still unclear. We prospectively investigated the relationship peritoneal with markers inflammation, angiogenesis, and membrane status, a focus on transporters. <i>Methods:</i> Seventy-one incident dialysis patients were assessed annual equilibration tests, using 3.86% glucose solution. Residual renal function including systemic intraperitoneal interleukin-6 (IL-6), effluent cancer antigen...
Pancreas-kidney transplantation (PKT) may significantly improve quality of life (HRQOL) in patients with type 1 diabetes. We have assessed the changes felt by PKT patients, using Gastrointestinal Quality Life Index (GIQLI) and EuroQol-5D questionnaires. Patients were asked to compare how their HRQOL had changed from pre-transplantation last visit. The 60 men 66 women enrolled a mean follow-up five yr; 84.1% both grafts, 15.9% one graft functioning. In all domains scores improved after PKT,...
Background. The determinants of peritoneal fast transport status at the beginning dialysis (PD) are still under debate. relationship between and inflammation or co-morbidity, its impact on patient survival not fully elucidated. Our objective was to investigate if in incident patients is associated with markers atherosclerosis, survival. Methods. Seventy-three PD performed a 3.86% equilibrium test (PET) 4.7±2.7 months after starting PD. Doppler carotid wall intima-media thickness (IMT)...
Summary Background and objectives Phosphate control impacts dialysis outcomes. Our aim was to define peritoneal phosphate transport in (PD) explore its association with hyperphosphatemia, clearance (PPhCl), PD modality. Design, setting, participants, & measurements Two hundred sixty-four patients (61% on continuous ambulatory [CAPD]) were evaluated at month 12. PPhCl calculated from 24-hour effluent. (Ph) creatinine (Cr) dialysate/plasma (D/P) a 4-hour 3.86% equilibration test. Results...
Peritonitis remains a common complication of peritoneal dialysis (PD). The aim this study was to analyze, in PD center, long-term temporal trends peritonitis rates, microbiology and outcomes. We treated 588 cases that occurred during 11,833.6 months at risk. Y-set twin-bag disconnecting systems were introduced 1990, mupirocin the exit site 2000 fluconazole prophylaxis 2005. Vancomycin ceftazidime empiric protocol. Global 5-year cohort rates expressed as episodes/patient-year (ep/p-y). A...
Reduced free water transport (FWT) through ultrasmall pores contributes to net ultrafiltration failure (UFF) and should be seen as a sign of more severe functional deterioration the peritoneal membrane. The modified equilibration test (PET), measuring dip in dialysate Na concentration, estimates only FWT. Our aim was simultaneously quantify small-solute transport, FWT, small-pore (SPUF) during single PET procedure.We performed 4-hour, 3.86% glucose PET, with additional measurement (UF) at 60...
Insulin resistance has been associated with cardiovascular disease in peritoneal dialysis patients. Few studies have addressed the impact of fast transport status or prescription on insulin resistance. The aim this study was to test whether is obesity parameters, rate, and glucose absorption.Insulin evaluated homeostasis model assessment method (HOMA-IR), additionally corrected by adiponectin (HOMA-AD). Enrolled patients were prevalent nondiabetics attending at Santo António Hospital...
ABSTRACT Longitudinal evolution of peritoneal protein loss (PPL), a reflection hydrostatic pressure–driven leak plasma proteins through the large‐pore pathway, is not clear. Time on PD causes mesothelial cells, vasculopathy, and increased thickness submesothelial fibrous layer. Are these structural changes associated with progressive increase PPL, in parallel rise D/P creatinine? The aim present study was to identify longitudinal PPL over time. This single‐center, included 52 dialysis (PD)...
[7][8][9][10][11][12][13][14][15] and was developed in concert with the Work Group responsible for this first wave of haemodialysis guidelines.
Background. A safe and well-functioning peritoneal catheter is fundamental for adequate dialysis (PD) treatment. Peritoneal implantation by Moncrief–Popovich (MP) technique might add several clinical advantages besides allowing timely access implantation. The aim of this study was to investigate the rate catheter-related complications survival in a single-centre university hospital PD unit, according method Methods. Four hundred sixty-seven consecutive Tenckhoff catheters were implanted...
Modelling competing risks is an essential issue in Nephrology Research. In peritoneal dialysis studies, sometimes inappropriate methods (i.e. Kaplan-Meier method) have been used to estimate probabilities for event of interest the presence risks. this situation a risk analysis should be preferable. The objectives study are describe bias resulting from application standard survival peritonitis-free patient and provide alternative statistical approaches taking into account. sample comprises...