- Anorectal Disease Treatments and Outcomes
- Pelvic floor disorders treatments
- Diverticular Disease and Complications
- Colorectal Cancer Surgical Treatments
- Esophageal and GI Pathology
- Gastrointestinal motility and disorders
- Clinical Nutrition and Gastroenterology
- Nutrition and Health in Aging
- Colorectal and Anal Carcinomas
- Congenital gastrointestinal and neural anomalies
- Gastroesophageal reflux and treatments
- Enhanced Recovery After Surgery
- Inflammatory Bowel Disease
- Myofascial pain diagnosis and treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Esophageal Cancer Research and Treatment
- Clinical practice guidelines implementation
- Musculoskeletal pain and rehabilitation
- Dysphagia Assessment and Management
- Genital Health and Disease
- Soft tissue tumor case studies
- Anesthesia and Pain Management
- Childhood Cancer Survivors' Quality of Life
- Urinary Bladder and Prostate Research
- Intestinal Malrotation and Obstruction Disorders
Amsterdam University Medical Centers
2022-2025
Bronkhorst (Netherlands)
2023
University of Amsterdam
2022
Bergman Clinics
2022
Maastricht University
2014-2016
University Medical Center
2016
Erasmus University Rotterdam
2004-2007
Postoperative convalescence is mainly determined by the extent and duration of postoperative ileus. This randomized clinical trial evaluated effects early oral feeding on functional gastrointestinal recovery quality life.One hundred twenty-eight patients undergoing elective open colorectal or abdominal vascular surgery participated in trial. Of these, 67 were to a conventional return diet, 61 regimen allowing resumption an diet as soon tolerated (free group).Reinsertion nasogastric tube was...
Abstract Background Feeding jejunostomy is frequently performed in patients undergoing oesophageal surgery, but can lead to serious complications. This prospective randomized trial compared the efficacy and complications of feeding with those nasoduodenal tube surgery. Methods Over an 18-month period, 150 consecutive resection were participate trial. Enteral access was by 79 71. started on first day after Results Full enteral took 3 days be established both groups. Minor catheter-related...
The most widely used classification for hemorrhoidal disease (HD) is the Goligher classification, which ranks presence and severity of prolapse in four grades. Since physicians base this gradation on medical history physical examination, it might be prone to interobserver variability. Furthermore, impacts treatment choice makes reproducibility utmost importance. aim study was determine variability among surgeons Netherlands.A single-choice survey used. first part consisted questions...
Functional constipation in children and adolescents is a common invalidating condition. In minority of patients, symptoms persist despite optimal conservative therapy. The aim this study was to evaluate whether the short-term effects sacral neuromodulation (SNM) with are sustained over prolonged period time.Patients aged 10-20 years, refractory constipation, fulfilling Rome III criteria, were included our study. If SNM test treatment showed >50 % improvement defecation frequency, permanent...
A nonrelaxing internal anal sphincter is present in a relatively large proportion of children with surgically treated Hirschsprung disease (HD) and can cause obstructive gastrointestinal symptoms. The short- long-term outcome adverse effects intrasphincteric botulinum toxin (Botox) injections obstruction after HD are evaluated.The Botox for symptoms was analyzed retrospective chart review between 2002 2013 the University Medical Centers Maastricht Nijmegen.A total 33 patients were included....
The aim of this Delphi study was to reach consensus on a new clinical decision tool help identify or exclude Crohn's disease (CD) in patients with perianal fistula(s) (PAF). A panel international experts the field proctology/inflammatory bowel invited participate. In first round (electronic survey), participants were asked anonymously provide their opinion probing (1) relevance and use characteristics suggestive underlying CD, (2) fecal calprotectin (FCP) for screening (3) diagnostic work-up...
The optimal management strategy for grade III hemorrhoids remains a subject of ongoing debate. Hemorrhoidectomy is the gold standard, but rubber band ligation offers less invasive outpatient alternative. Treatment variability persists due to lack consensus on preferred strategy. To directly compare effectiveness and hemorrhoidectomy in treatment hemorrhoids. Open-label, parallel-group, randomized controlled non-inferiority trial. Multicenter study across 10 Dutch hospitals from October 2019...
van Oostendorp, Justin Y. MD; Dekker, Lisette MD PhD; Dieren, Susan Veldkamp, Ruben Bemelman, Willem A. Han-Geurts, Ingrid J.M. On behalf of The HollAND Study group Author Information
After recognition of the importance early postoperative enteral feeding, placement a feeding jejunostomy as an adjunct to gastrointestinal surgery has become widely accepted. However, little attention been paid surgical complications and their consequences. Feeding esophageal resection reconstruction can lead serious complications.Between 1978 2000, 1,387 patients underwent reconstruction. Of these, 1,166 received needle catheter at end operation. All were prospectively evaluated in database...
<i>Background:</i> Nutritional condition is one of the factors determining postoperative outcome in esophageal surgery. This study explored relation between preoperative nutritional status and infectious complications. <i>Methods:</i> From a prospective database, 400 patients who underwent resection for malignancy were selected. Preoperative was assessed by body mass index, prognostic index (PNI), risk (NRI) weight loss. The association parameters complications...
Abstract Background Anorectal function tests are helpful for objective investigation of anorectal (dys)function. A variety available, but there is no recommendation when to perform which test. Furthermore, test the most accurate controversial and correlation between these not very clear. The aim our study was examine anal pressures possibility diagnose pelvic floor dyssynergia digital rectal examination (DRE) several tests. Methods Between January 2020 April 2022, all men women aged 18 80...
Abstract Background Although studies have shown that early oral feeding after abdominal surgery is feasible, many surgeons still advocate a careful, slow introduction of postoperative feeding. This study was conducted to investigate whether patient-controlled possible in patients undergoing colonic or aortic surgery. Methods A randomized clinical trial compared (PC group) with fixed regimen (FR group). Patients the PC group (n = 56) received when they requested it; FR 49) started normal diet...
Anorectal pain is a symptom which may have both structural and functional causes, can, sometimes, develop into chronic syndrome. Functional causes in particular are challenging to treat when conservative treatment measures fail. Botulinum toxin A (BTX-A) can be applied relax the anal sphincter and/or levator ani muscle break vicious circle of contraction. In our tertiary referral proctology clinic, we evaluated outcome patients treated with BTX-A for anorectal pain. Our electronic database...
Abstract Background A chronic anal fissure is a common, painful condition with great impact on daily life. The exact pathogenesis has not been fully elucidated and treatment varies. large percentage of patients experience pelvic floor dysfunction (dyssynergia increased muscle tone). aim our study was to investigate the effect physical therapy in fissure. Methods Between December 2018 July 2021, at Proctos Clinic Netherlands, were randomly assigned an intervention group, receiving 8 weeks...
Perianal fistulas are a debilitating complication of Crohn's disease (CD). Due to unknown reasons, CD-associated in general more difficult treat than cryptoglandular (non-CD-associated). Understanding the immune cell landscape is first step towards development effective therapies for fistulas. In this work, we characterized composition and spatial localization disease-associated cells both types perianal by high-dimensional analyses.
Abstract Background Management of cryptoglandular fistula-in-ano (FIA) can be challenging. Despite Dutch and international guidelines determining optimal therapy is still quite difficult. The aim this study was to report current practices in the management FIA among gastrointestinal surgeons Netherlands. Methods residents who are treating regularly were sent a survey invitation by email. available online from September 19 December 1 2019. questionnaire consisted 28 questions concerning...
Chronic anal fissure (CAF) is a common, bothersome condition frequently accompanied by pelvic floor complaints. Despite current guidelines, optimal management challenging. The aim of this study to evaluate CAF among gastrointestinal surgeons in the Netherlands.Dutch and residents were sent survey invitation email, which was available online between June 2021 September 2021. questionnaire consisted 21 questions concerning work experience, physical examination, diagnostic surgical techniques,...
Abstract Aim The aim of this work was to determine the clinical efficacy high‐volume transanal irrigation (TAI) in patients with constipation and/or faecal incontinence using validated symptom and quality life questionnaires. Method This a prospective cohort study 114 consecutive (Rome IV defined) who started TAI. A comprehensive questionnaire completed at baseline 4, 12, 26 52 weeks’ follow‐up. primary objective significant reduction [≥30%; Cleveland Clinic Constipation Score (CCCS) St...
Perianal fistula surgery can damage the anal sphincters which may cause faecal incontinence. By measuring regional pressures, 3D-HRAM potentially provides better guidance for surgical strategy in patients with perianal fistulas. The aim was to measure pressures and compare these 3D-EUS findings Consecutive active fistulas who underwent both at a clinic specialised proctology were included. A group of 30 without served as controls. Data regarding demographics, complaints, previous procedures...
Abstract Introduction Haemorrhoidal disease (HD) is a common condition with significant epidemiologic and economic implications. While it possible to treat symptomatic grade 1–2 haemorrhoids rubber band ligation (RBL) or sclerotherapy (SCL), the effectiveness of these treatments compatible current standards has not yet been investigated randomised controlled trial. The hypothesis that SCL inferior RBL in terms symptom reduction (patient-related outcome measures (PROMs)), patient experience,...
Anorectal manometry measurements exhibit significant interrater variability. Newer techniques like 3D high-resolution anorectal (3D-HRAM) have the potential to enhance diagnostic accuracy and our understanding of defecation disorders. However, extent variability in 3D-HRAM is still unknown. Between January 2020 April 2022, patients referred for pelvic floor physical therapy (PFPT) due functional complaints underwent testing. In a retrospective analysis, three expert raters independently...