A5063280427- Advanced Radiotherapy Techniques
- Breast Cancer Treatment Studies
- Radiation Therapy and Dosimetry
- Medical Imaging Techniques and Applications
- Radiation Effects and Dosimetry
- Breast Implant and Reconstruction
- Breast Lesions and Carcinomas
- Glioma Diagnosis and Treatment
- Management of metastatic bone disease
- Brain Metastases and Treatment
- Radiation Dose and Imaging
- COVID-19 and Mental Health
- Advanced X-ray and CT Imaging
- Glutathione Transferases and Polymorphisms
- COVID-19 and healthcare impacts
- Cancer Treatment and Pharmacology
- Head and Neck Cancer Studies
- Medical Imaging and Analysis
- Body Image and Dysmorphia Studies
- Effects of Radiation Exposure
- Drug-Induced Hepatotoxicity and Protection
- Lung Cancer Treatments and Mutations
- Neurosurgical Procedures and Complications
- Radiation Detection and Scintillator Technologies
- BRCA gene mutations in cancer
Altınbaş University
2024-2025
Bahçeşehir University
2023
Acıbadem University
2018-2022
Istanbul Medipol University
2014-2019
Istanbul Aydın University
2018
Importance Increasing evidence supports the oncologic safety of de-escalating axillary surgery for patients with breast cancer after neoadjuvant chemotherapy (NAC). Objective To evaluate outcomes among clinically node (cN)–positive and whose disease became cN negative NAC (ycN negative). Design, Setting, Participants In NEOSENTITURK MF-1803 prospective cohort registry trial, from 37 centers cT1-4N1-3M0 treated sentinel lymph biopsy (SLNB) or targeted dissection (TAD) alone ypN-negative...
Abstract Background: Previous prospective studies reported decreased false negative rates in patients presenting with T1-3/cN1 disease, the removal of 2 or more sentinel lymph nodes (SLNs), using combined technique for SLN biopsy (SLNB), and by targeted axillary dissection (TAD) initially clinically node-positive after neoadjuvant chemotherapy (NAC). The aim this study is to compare feasibility oncological safety TAD SLNB cN-positive/ycN0 breast cancer following NAC a study. Methods: This...
Abstract Background The omission of axillary lymph node dissection (ALND) remains controversial for patients with residual disease after neoadjuvant chemotherapy (NAC), regardless the burden. This study evaluated oncologic safety and factors associated outcomes in disease. These were treated solely sentinel biopsy (SLNB) or targeted (TAD), without ALND, NAC. Methods A joint analysis two different multicenter cohorts—the retrospective cohort registry MF18‐02 prospective observational MF18‐03...
Malnutrition is one of the most common complications cancer and its treatments with a prevalence up to 80% among patients. Thus, standardized target-oriented attitudes oncologists toward nutritional management are particularly important. This study aims report questionnaire-based evaluation different views medical nutrition radiation purpose underline problems requirements nutrition. A national web-based survey composed 26 multiple choice questions about participant demographics, level...
Postmastectomy reconstructive surgery for cosmetic satisfaction of patients is rapidly increasing. Postoperative complications such as infection, capsular contracture, implant loss are more common in who receive adjuvant radiotherapy (RT) than those do not. Satisfaction levels still a controversial issue. Therefore, we wanted to investigate our patient population the effects RT and planned study evaluating rates received implants.Seventy five breast cancer went through mastectomy...
Purpose: Brain stereotactic radiosurgery (SRS) involves the use of precisely directed, single session radiation to create a desired radiobiologic response within brain target with acceptable minimal effects on surrounding structures or tissues. In this study, dosimetric comparison GammaKnife perfection and Cyberknife M6 treatment plans were made. Methods: Treatment plannings done for unit using Gammaplan planning system (TPS) CT scan head neck randophantom simulating sterotactic treatments...
The objective of our study is to evaluate breast cancer patients with BRCA1 or BRCA2 gene mutations and compare them without these mutations. Specifically, we aim assess the acute side effects radiotherapy in both groups.
Purpose: Brain stereotactic radiosurgery involves the use of precisely directed, single session radiation to create a desired radiobiologic response within brain target with acceptable minimal effects on surrounding structures or tissues. In this study, dosimetric comparison Truebeam 2.0 and Cyberknife M6 treatment plans were made. Methods: For machine, planning done using 2 full arc VMAT technique 6 FFF beam CT scan Randophantom simulating sterotactic treatments for one metastasis. The dose...
Increased stress levels caused by the pandemic might cause delays in cancer treatment. We conducted a survey among patients undergoing treatment to evaluate their psychological wellbeing and adherence during Coronavirus disease 19 (COVID-19) pandemic.Patients receiving active chemotherapy at private oncology center between January May 2021 were included. Healthy volunteers employees of district health directorate with no history or chronic disease. Treatment was described as compliant if...
Abstract Aim The accuracy of two calculation algorithms the Varian Eclipse treatment planning system (TPS), electron Monte Carlo algorithm (eMC) and general Gaussian pencil beam (GGPB) for calculating peripheral dose distribution beams was investigated. Methods Peripheral measurements were carried out 6, 9, 12, 15, 18 22 MeV using parallel plate ionisation chamber EBT3 film in slab phantom. Measurements performed 6×6, 10×10 25×25 cm 2 cone sizes at d max each energy up to 20 beyond field...
OBJECTIVETrigeminal neuralgia (TN) is a common craniofacial pain syndrome manifested by the episodes of severe lancinating along sensory region trigeminal nerve.Vascular compression theory has been postulated as main cause TN in root entry zone nerve.Microvascular decompression surgery most effective surgical option for treatment TN.Gamma knife (GKS) minimally invasive drug-resistant (TN).We aimed to investigate instant and early relief 12 consecutive patients. METHODSThis clinical study was...
614 Background: In experimental and clinical trials, tamoxifen (TAM) has been shown to increase radiation-induced lung fibrosis (RILF). Aromatase inhibitors (AI) are superior TAM in the adjuvant setting, preclinical data suggest that letrozole (LET) sensitizes breast cancer cells ionizing radiation. However, poor available regarding toxicity of concurrent use AI radiation therapy (RT). this study, we evaluated whether have any impact on development RILF rats. Methods: 60 female wistar-...
Purpose: The effect of diagonal profiles measured with different types detectors to the improvement quality algorithm configuration is analysed. Methods: For commissioning Truebeam STx machine, Eclipse requires a largest field size. left side beam profile 5cm overscan at depths 30cm for 40×40cm 2 100cm SSD was scanned. scan made using PTW 0.125cc semiflex ionization chamber and microDiamond 0.004mm 3 sensitive volume. Two machnines were created in same data except profiles. A single 6 FFF...
Purpose: The surface dose of flattening filter free beams is higher than conventional beams. In this study, effect thermoplatic mask to the in sterotactic brain treatments was compared using EBT3 Gafchromic film and OSL dosimeter. Methods: Treatment planning were done 2 full arc VMAT technique with 6 FFF beam on CT scan Randophantom simulating treatment for one metastasis.1×1 cm EBT 3 pieces placed under thermoplastic lens phantom. Then dosimeter also at same way place. phantom irradiated...
Purpose: Stereotactic radiosurgery for spine metastases involves irradiation using a single high dose fraction. The purpose of this study was to dosimetrically compare stereotactic radiosurgery(SRS) plans recently new volumetric modulated arc therapy(VMAT) technique against fix-field intensity-modulated radiotherapy(IMRT). Plans were evaluated target conformity and spinal cord sparing. Methods: Fifteen previously treated patients replanned the Eclipse 10.1 TPS AAA calculation algorithm. IMRT...
The aim of this study is to evaluate the reliability MRI fusion when determining intracranial target volume performing CT based stereotactic radiosurgery. Patients treated with radiosurgery various diagnosis are included in study. All patients were immobilized using thermoplastic masks prior simulation. planning was obtained both and without iv contrast 1mm slice thickness. images then fused 3D, T1 weighted MR by two different platforms (Eclipse 10.0, Velocity 3.0 rigid deformable)....