A5050836467- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Effects of Radiation Exposure
- Ultrasound and Hyperthermia Applications
- Medical and Biological Ozone Research
- Bariatric Surgery and Outcomes
- Biliary and Gastrointestinal Fistulas
- Lipid metabolism and disorders
- Anesthesia and Sedative Agents
- TGF-β signaling in diseases
- NF-κB Signaling Pathways
- Frailty in Older Adults
- Obesity and Health Practices
- Hydrogen's biological and therapeutic effects
- Gastrointestinal disorders and treatments
- Phytochemical Studies and Bioactivities
- Bone Metabolism and Diseases
- Paraoxonase enzyme and polymorphisms
- Biomarkers in Disease Mechanisms
- Gastroesophageal reflux and treatments
- Genetic factors in colorectal cancer
- Diagnosis and Treatment of Venous Diseases
- Vitamin D Research Studies
- Phytochemistry and Bioactive Compounds
- Thyroid and Parathyroid Surgery
Sağlık Bilimleri Üniversitesi
2018-2023
Mimar Sinan Güzel Sanatlar Üniversitesi
2019-2021
Bağcılar Eğitim ve Araştırma Hastanesi
2015-2020
Ergani Devlet Hastanesi
2019
The present study investigated the potent therapeutic effects of Ruscogenin, main steroid sapogenin traditional Chinese plant called 'Ophiopogon japonicas', on chronic ulcer model established with acetic acid in rats.24 rats were attenuated to sham (2 ml/kg/day isotonic solution), control (untreated ulcer) and treatment (3 ruscogenin) groups. After for 2 weeks, gastric tissues collected prepared light microscopic (H&E), immunohistochemical (Collagen I, III IV) biochemical analysis [Epidermal...
Objective The most vital complications of thyroidectomy are recurrent nerve damage and hypocalcaemia. We aimed to compare the tissue perfusion scores (PS) IG fluorescence angiography (IGFA) visual examination by surgeon after total thyroidectomy. Subjects methods Forty-three patients were accepted into study. Localisation parathyroid gland (PG) was determined naked eye scored in terms perfusion. averages fluorescent light intensities for each IGFA calculated, perfusions compared with PS...
Radiation proctitis (RP) is inflammation and damage to the rectum, manifested secondary ionizing radiation utilized for treatment. In this study, we evaluated anti-inflammatory therapeutical protective effects of ruscogenin in a model acute RP.Thirty-two Sprague-Dawley rats were divided into 4 groups (n = 8) as sham, control, treatment, prophylaxis groups. Prophylaxis group treatment dosed by oral gavage 14 days pre- postradiation. At end 28th day, all subjects sacrificed.Histopathological...
To determine the potential protective and therapeutic effects action mechanism of ruscogenin on cerulein-induced acute pancreatitis (AP) model in rats.Overall, 32 rats were attenuated to sham (2-mL/kg/day isotonic solution for 4 weeks), control (20-µg/kg AP 12 hours), prophylaxis groups (cerulein-induced following 3-mL/kg/day weeks) treatment (3-mL/kg/day hours). Blood samples collected biochemical analysis nitric oxide synthase 1 (NOS1/neuronal NOS), malondialdehyde (MDA) intercellular...
We aimed to examine the potential anticancer effects of ozone applied after chemotherapeutic treatment with different concentrations doxorubicin in Luminal-A subtype human breast cancer cell line (MCF-7) and compare results on L929 fibroblast line.Both lines were incubated increasing doses (1-50 μM) for 24 h at 37°C. Then, half groups 30 μg/mL 25 min as combination groups. Cell viability was analyzed by MTT assay, apoptosis flow cytometry, levels tumor necrosis factor alpha, transforming...
Purpose: To investigate the prophylactic and therapeutical effects of sildenafil in a model acute radiation proctitis (ARP). Methods: All experimental procedures this study was examined by histopathological, immunohistochemical transmission electron microscopic analysis. Results: Our histopathological evaluations indicated significant increases lesion severity, cryptic apsis, cryptitis, distortion, reactive atypia infiltration depth control (proctitis) group. While prophylaxis group...
There are many complications of meshes in hernia repair. The aim this study was to investigate the effects onlay titanium-coated (TCM) on recurrence, foreign body sensation and chronic pain ventral In retrospective study, 160 patients undergone TCM or polypropylene mesh (PM) surgery for repair were examined between May 2014 January 2018 at our center. Patient characteristics, type hernia, defect size, operative time, follow-up surgical site occurrence (infection, seroma hematoma), analyzed....
Amaç: Bu non-invaziv retrospektif klinik çalışmada, yanık merkezimizde takip ve tedavi ettiğimiz geriatrik yaş gurubu hastalarda mortaliteyi etkileyen faktörleri incelemeyi amaçladık. Materyal Metot: Yanık merkezinde 2016 Ocak ile 2019 tarihleri arasında yataklı servis yoğun bakım servisinde edilen grubunda (65 üzeri) 86 hasta dahil edilmiştir. Hasta dosyaları yaş, cinsiyet, etiyolojisi, yüzdesi [total vücut yüzey alanı (TVYA)], bölgesi, serviste/yoğun bakımda yatış süresi, eşlik eden...
Purpose To investigate the efficacy of cordycepin, an adenosine analogue, on prevention esophageal damage and stricture formation due to caustic burns in rat model comparing with prednisolone. Methods Caustic burn was introduced by 37.5% NaOH distal esophagus. Thirty-two Wistar albino rats were divided four groups: sham undergone laparotomy, treated 0.9% NaCl; control injured without cordycepin treatment; group NaOH, 20 mg/kg cordycepin; prednisolone 1 for 28 days. Efficacy assessed...
Objective:We assessed the impact of pacing mode on long-term clinical outcomes in cases with complete atrioventricular block (CAB). Method:We retrospectively analyzed 161 patients CAB, who undergone a cardiac permanent pacemaker.Of involved physiologic (PP) group, 95 were VDD and 14 DDD mode.In ventricular (VP) VVI mode, there 52 patients. Results:The average age was 66±13 years follow-up duration 40.2±22.6months.Atrial fibrillation (AF) observed to be significantly more common VP group than...