A5039946112- Photodynamic Therapy Research Studies
- Nanoplatforms for cancer theranostics
- Porphyrin and Phthalocyanine Chemistry
- Cancer, Hypoxia, and Metabolism
- Medical and Biological Ozone Research
- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- Nonmelanoma Skin Cancer Studies
- Click Chemistry and Applications
- Biosensors and Analytical Detection
- Reproductive System and Pregnancy
- Bone and Joint Diseases
- Insect and Arachnid Ecology and Behavior
- Biomarkers in Disease Mechanisms
- Hematological disorders and diagnostics
- Air Quality and Health Impacts
- Natural product bioactivities and synthesis
- Water Quality Monitoring Technologies
- Blood groups and transfusion
- Bioactive Compounds and Antitumor Agents
- Microfluidic and Bio-sensing Technologies
- Advanced Radiotherapy Techniques
- Autoimmune and Inflammatory Disorders Research
- Hydrogen's biological and therapeutic effects
- Photochromic and Fluorescence Chemistry
Istanbul University
2022-2024
Istanbul Health and Technology University
2021-2024
Sağlık Bilimleri Üniversitesi
2021-2023
Bağcılar Eğitim ve Araştırma Hastanesi
2023
This study aimed to determine whether vitamin C (VC) and E (VE) can effectively protect the femoral head reduce risk of developing osteonecrosis in rats that have been treated with steroids.The was conducted on 30 young adult male Sprague-Dawley (mean weight: 356±18 g; range, 330 375 g), which were randomly assigned one five groups. The control group received saline solution, while other groups given lipopolysaccharide/methylprednisolone (LPS/MPS) induce osteonecrosis. Three induced also...
In this study, we aimed to evaluate the antioxidant, anti-apoptotic, osteoblastic and hypolipidemic effects of thymoquinone (TQ) treatment on steroid-induced osteonecrosis femoral head (ONFH) model in rats.A total 24 rats were randomly divided into four groups: control group administered saline; TQ 10 mg/kg/day orally; lipopolysaccharide/methylprednisolone (LPS/MPS) 20 µg/kg intraperitoneally LPS 40 mg/kg intramuscularly MPS establish ONFH model; LPS/ MPS+TQ both LPS/MPS and, then, once...
We aimed to examine the potential anticancer effects of ozone applied after chemotherapeutic treatment with different concentrations doxorubicin in Luminal-A subtype human breast cancer cell line (MCF-7) and compare results on L929 fibroblast line.Both lines were incubated increasing doses (1-50 μM) for 24 h at 37°C. Then, half groups 30 μg/mL 25 min as combination groups. Cell viability was analyzed by MTT assay, apoptosis flow cytometry, levels tumor necrosis factor alpha, transforming...
Photodynamic Therapy (PDT) is a treatment option for cancer. Singlet oxygen produced as result of the photochemical reaction between light, photosensitizer (PS), and molecular oxygen, which kills cells. One most prevalent cancers, affecting 1.23 million people worldwide, colon Surgery sole curative option; however, large proportion patients experience local recurrence or distant metastases. therapy an alternative cancer.Aim: MTT assays were used to assess cell viability, respectively....
Photodynamic Therapy (PDT) is a cancer treatment. Singlet oxygen produced as result of the photochemical reaction between light, photosensitizer (PS), and molecular oxygen, which kills cells. Colon cancer, affecting 1.23 million people worldwide, often requires surgery but has high recurrence metastasis rates. therapy represents an alternative treatment for colon cancer. This study used MTT assays to evaluate cell viability applied Zinc (II) Phthalocyanine (ZnPc) photosensitizers colorectal...
Son yıllarda anti-bakteriyel direnç olgusu, bakterilerin neden olduğu hastalıklarla mücadelede daha fazla sorun haline gelmiştir. Biz bu çalışmayla, açık yara ve yanıkların fırsatçı patojeni olan Pseudomonas aeruginosayı etkili bir yöntemle inaktive etmeyi fotodinamik inaktivasyon(PDI) gelişimine katkıda bulunmayı hedefledik. aeruginosa bakterisini, vitamin B kompleksi lazer ile olduğunu spektrofotometrik ölçümler antimikrobiyal madde etkinliği analiz yöntemleriyle gösterdik. Ayrıca PDI'nin...
Amaç: Kolon kanserleri, hastanın yaşam kalitesini derinden etkileyen ve çeşitli komplikasyonlarla ilişkili kronik ölümcül bir hastalıktır. Vitamin B kompleksi, gıda takviyesi olarak alındığında olumlu anti-inflamatuar etkiler göstermektedir. Bu çalışma, fotodinamik terapiyle lipozomlu vitamin kompleksinin kolon kanserlerinde (HCT-116 HT-29 hücre hattı) anti-kanser etkisini araştırmayı amaçlamıştır. Materyal- Metot: Çalışmanın birinci basamağını oluşturan kompleksi lipozom ile kapsüle edildi....
Günümüz dünyasında gelişen teknoloji ile su, gıda ve çevresel kirliliğin artmasıyla bu temel ihtiyaçların sağlık kontrolü oldukça zorlayıcıdır. Bu tür eksiklerin giderilmesi üzerine bir çalışma olmuştur. amaçla iki aşamalı iş planı oluşturulmuştur. Birincisi; hedef bakteriye seçici tepki veren biyomoleküllerden olan proteinoidler sentezlenip karakterize edilmiştir. Şuana kadar kullanılan biyolojik tanıma elemanlarından ilk defa farklı olarak kullanılmıştır. İkinci aşamada ise proteinoidler,...