Tuğba Elgün

ORCID: 0000-0002-1311-6892
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Research Areas
  • Photodynamic Therapy Research Studies
  • Reproductive Biology and Fertility
  • Sperm and Testicular Function
  • Dental materials and restorations
  • Endodontics and Root Canal Treatments
  • Nanoplatforms for cancer theranostics
  • Dental Implant Techniques and Outcomes
  • Ethics and Legal Issues in Pediatric Healthcare
  • Ovarian function and disorders
  • Click Chemistry and Applications
  • Cancer, Hypoxia, and Metabolism
  • Blood groups and transfusion
  • Reproductive System and Pregnancy
  • Pregnancy and preeclampsia studies
  • Assisted Reproductive Technology and Twin Pregnancy
  • Gestational Diabetes Research and Management
  • Dermatoglyphics and Human Traits
  • Parvovirus B19 Infection Studies
  • ATP Synthase and ATPases Research
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Neurogenesis and neuroplasticity mechanisms
  • Cell death mechanisms and regulation
  • Multiple Sclerosis Research Studies
  • Periodontal Regeneration and Treatments
  • MicroRNA in disease regulation

Biruni University
2018-2024

Sağlık Bilimleri Üniversitesi
2023

Istanbul University
2015

Objective: Alpha thalassemia syndromes are caused by mutations on one or more of the four α-globin genes.Mutations could be either commonly deletional non-deletional.As some deletions (3.7 and 4.2) cause α + -thalassemia, (-20.5, MED, THAI, FIL) 0 -thalassemia.The aim this study was to determine alpha in patients with unsolved hypochromic microcytic anemia evaluate types mutations.Material Methods: Two hundred six were evaluated for thalassemia.A venous blood sample 2 mL drawn from each...

10.4274/tjh.2014.0204 article EN Turkish Journal of Hematology 2015-12-05

Abstract Backround: The in vitro cytotoxic effects of six different clear aligner materials were evaluated using the MTT analysis. Methods: material samples [Duran (ScheuDental GmbH, Iserlohn, Germany), Zendura-Flx (Bay Materials LLC, Fremont, CA, USA), Taglus (Laxmi Dental Export Pvt. Ltd, Mumbai, India), Smart Track (Align Technology, San Jose, Zendura Essix C + (Essix ® (Raintree Essix, Inc., 4001 Division St, Metairie, LA-USA)] initially kept a saline solution airtight test tubes for 8...

10.2478/aoj-2022-0034 article EN cc-by Australasian Orthodontic Journal 2022-01-01

Photodynamic Therapy (PDT) is a cancer treatment. Singlet oxygen produced as result of the photochemical reaction between light, photosensitizer (PS), and molecular oxygen, which kills cells. Colon cancer, affecting 1.23 million people worldwide, often requires surgery but has high recurrence metastasis rates. therapy represents an alternative treatment for colon cancer. This study used MTT assays to evaluate cell viability applied Zinc (II) Phthalocyanine (ZnPc) photosensitizers colorectal...

10.17344/acsi.2024.8948 article EN Acta chimica slovenica 2024-12-13

Photodynamic Therapy (PDT) is a treatment option for cancer. Singlet oxygen produced as result of the photochemical reaction between light, photosensitizer (PS), and molecular oxygen, which kills cells. One most prevalent cancers, affecting 1.23 million people worldwide, colon Surgery sole curative option; however, large proportion patients experience local recurrence or distant metastases. therapy an alternative cancer.Aim: MTT assays were used to assess cell viability, respectively....

10.2139/ssrn.4822834 preprint EN 2024-01-01

Objective: To compare clinical pregnancy rate through ICSI-ET between polycystic ovarian syndrome patients and women with normal ovaries (control group). We also investigated whether serum Anti-Müllerian hormone level or LH/FSH ratio may predict in both groups.Study Design: In this retrospective study, endocrine/ parameters cycle characteristics of (n=32) (n=115) aged <40 years were evaluated.Results: Clinical group did not differ from that the control (31.3% vs. 32.2%, p>0.05,...

10.21613/gorm.2018.897 article EN cc-by Gynecology Obstetrics and Reproductive Medicine 2019-04-17

Testis gelişimi sırasında gerçekleşen apoptozun germ hücrelerinin kontrolü için gerekli olduğu ortaya konmuştur. Hücre ölümü; “caspase-bağımlı” ya da mitokondriden salınan AIF gibi çeşitli proapoptotik faktörler aracılığıyla “caspase-bağımsız” olmak üzere iki şekilde düzenlenir. PARP-1’in aşırı aktivasyonunun hücre ölümünde önemli bir rolü bilinmektedir. Caspase-bağımlı apoptotik süreçlerde etkin bilinen fare testis gelişiminde olup olmadığı bilinmemektedir. Bu çalışmanın amacı, postnatal...

10.32708/uutfd.422147 article TR Uludağ Üniversitesi Tıp Fakültesi Dergisi 2018-08-01

The aim of this study was to investigate the effects Cysteamine (Cys) and Fetal Calf Serum (FCS) in Synthetic Oviduct Fluid (SOF) Charles Rosenkrans (CR1aa) on bovine vitro embryo production its ability freeze. oocytes were divided into two groups allowed mature TCM-199, with without cysteamine. They 4 subgroups according whether they contain Cys FCS 2 different culture media (SOF CR1aa). Accordingly, 8 formed as SOF+FCS+Cys, SOF+Cys, SOF+FCS, S Dulbeco's OF, CR1aa+FCS+Cys, CR1aa+Cys,...

10.33988/auvfd.681452 article EN Ankara Üniversitesi Veteriner Fakültesi Dergisi 2020-07-17

Aim: The clinical suitability of restorative dental materials is determined by evaluating their biocompatibility, and physical chemical properties.The present study examined the cytotoxic effects three different on human pulp stem cells (DPSCs).Material Methods: In this study, composite, high-viscosity glass ionomer cement (HVGIC), an alkasite were used.In total, 12 samples each material prepared for cytotoxicity assays.Cytotoxic considering biomaterial releases.Cell viability proliferation...

10.4328/acam.21846 article EN The Annals of Clinical and Analytical Medicine 2023-01-01

Change in the level of inflammatory cytokine and total antioxidant obese patients Investigation change

10.4328/acam.21813 article EN The Annals of Clinical and Analytical Medicine 2023-01-01

Abstract Objectives: In this study, it was aimed to investigate the possible effects of oral chewable probiotic tablets (PTs) produced directly support flora on proliferation human dental pulp stem cells (DPSCs) and gingival fibroblast (HGFCs). Materials Methods: For analysis in “Motiflor AS,” a PT that dissolves mouth, containing 13.5mg Lactobacillus helveticus Rosell-52, L. rhamnosus Rosell-11, halivarus HA-118, Bifidobacterium longum Rosell-175 used. Cell survival were analyzed by...

10.4103/jcde.jcde_125_23 article EN Journal of Conservative Dentistry and Endodontics 2023-10-27

Abstract Background: The clinical suitability of restorative dental materials is also determined by their biocompatibility, in addition to physical and chemical properties. present study aimed examine the cytotoxic effects three on human pulp stem cells (DPSCs). Methods: This examined properties a composite (Gradia Direct,GC Europe), high-viscosity glass ionomer cement (HVGIC; Equia Forte,GC an alkasite material (Cention N,Ivoclar Vivadent). In total, 12 samples each were prepared for...

10.21203/rs.3.rs-1317815/v1 preprint EN cc-by Research Square (Research Square) 2022-02-07

Abstract Objective: The aim of this study was to analyze visual data analysis nanotubes formation and actin expression between Sertoli germ cells, gene silencing with the use FAK siRNA EF application, confirmation mRNA levels, cell viability test immunofluorescent staining associated ezrin, Fascin 1, N-cadherin. Expressions blood-testicular barrier (BTB) proteins were evaluated. Materials Method: As experimental group research; control (CG), in which intercellular cargo followed under normal...

10.21203/rs.3.rs-2357692/v1 preprint EN cc-by Research Square (Research Square) 2022-12-21
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