A5031908718- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Neonatal Health and Biochemistry
- Acute Lymphoblastic Leukemia research
- Erythrocyte Function and Pathophysiology
- Birth, Development, and Health
- Acute Myeloid Leukemia Research
- Blood disorders and treatments
- Hepatitis B Virus Studies
- Folate and B Vitamins Research
- Trace Elements in Health
- Blood groups and transfusion
- Hepatitis C virus research
- Gestational Diabetes Research and Management
- Metabolism and Genetic Disorders
- Chronic Myeloid Leukemia Treatments
- Childhood Cancer Survivors' Quality of Life
- Cardiovascular Function and Risk Factors
- Neurological and metabolic disorders
- Healthcare and Venom Research
- Nail Diseases and Treatments
- Diet, Metabolism, and Disease
- Methemoglobinemia and Tumor Lysis Syndrome
- Ethics and Legal Issues in Pediatric Healthcare
- Respiratory viral infections research
Ministry of Health
2025
Sağlık Bilimleri Üniversitesi
2018-2024
University of Health Sciences Antigua
2022-2024
Şişli Etfal Eğitim ve Araştırma Hastanesi
2010-2024
University of Health Sciences
2022-2023
Palmetto Hematology Oncology
2021
İstanbul Eğitim ve Araştırma Hastanesi
2019
Orient-Institut Istanbul
2018
Isovaleric acidemia is a rare autosomal recessive inborn error of leucine metabolism. Two phenotypes with either an acute neonatal or chronic intermittent presentation were described. The type observed more frequently and fatal. We report the case girl in childhood who presented hyperglycemia metabolic acidosis increased anion gap; preliminarily diagnosed as diabetic ketoacidosis, but further investigation revealed isovaleric academia. This interest because rarity this presentation....
Objective: Alpha thalassemia syndromes are caused by mutations on one or more of the four α-globin genes.Mutations could be either commonly deletional non-deletional.As some deletions (3.7 and 4.2) cause α + -thalassemia, (-20.5, MED, THAI, FIL) 0 -thalassemia.The aim this study was to determine alpha in patients with unsolved hypochromic microcytic anemia evaluate types mutations.Material Methods: Two hundred six were evaluated for thalassemia.A venous blood sample 2 mL drawn from each...
Since the beginning of Syrian civil war, more than 3.5 million Syrians have been under temporary protection status in Turkey. Because beta-thalassemia (BT) is a prevalent disorder Mediterranean countries, we decided to estimate prevalence and make an overview demographic, socioeconomic, medical characteristics, healthcare problems refugee children with BT.Eighteen Turkish Pediatric Hematology Oncology Centers (PHOC) 318 from 235 families participated study. The mean age patients was 8.1 ±...
Purpose: Familial Mediterranean Fever (FMF) is an autosomal recessive, auto-inflammatory disease that characterized by recurrent fever and polyserositis episodes like peritonitis, arthritis, pleuritis. The occurs most commonly in populations of Jewish, Turkish, Armenian, Arabian origin. We aimed to show the genotype-phenotype relationship FMF patients our centre. Materials Methods: conducted a retrospective analysis medical registries 200 pediatric from Sisli Hamidiye Etfal Education...
Adolesanlar ve
Background: Delayed diagnosis of hypothyroidism may result in atypical presentations. Here, we report a case with decreased serum level and activity von Willebrand factor due to untreated profound Observation: A 9-year-old girl, presented prolonged gingival bleeding after dental extraction. Clinical findings the were consistent hypothyroidism, laboratory workup results revealed associated hypothyroidism. Restoration euthyroidism normalized coagulation parameters. Conclusion: lead...
Glucose-6-phosphatase catalytic subunit 3 (G6PC3) deficiency is a recently identified form of congenital neutropenia associated with developmental anomalies. The severity and the clinical spectrum are highly variable. Aside from infectious complications extrahematologic features, inflammatory bowel disease autoinflammatory less frequently observed manifestations. However, amyloidosis has never been reported in G6PC3 deficiency. Here, we present 12-year-old patient incidentally discovered...
Amaç:
Background: The aim of this study was to compare the efficacies saline solutions different concentrations used for management infants with mild moderate bronchiolitis.Methods: A retrospective chart review 46 children, aged 1-24 months, diagnosed acute bronchiolitis performed. patients were separated into 2 groups: normal and 3% hypertonic saline. Length hospital stay, modified respiratory assessment score (MRAS) at admission, 48 hours admission discharge compared.Results: MRAS evaluated...
<h3>Aim</h3> Febrile neutropenia (FN) is a common cause of mortality and morbidity in children with cancer, which necessitates prompt antibiotherapy. Antibiotic administration within one hour recommended accepted as quality-of-care measure developed countries. The goal this study to assess the impact time antibiotic (TTA) on prognosis febrile treated for cancer Istanbul. <h3>Material Method</h3> patients chemotherapy-associated FN between ages 1 month 18 years our center were prospectively...
Vitamin B12, an indispensable micronutrient, is pivotal in numerous physiological processes, with particular significance during pregnancy and fetal development. The increasing adoption of vegetarian diets the economic challenges associated accessing animal-based food sources contribute to prevalence vitamin B12 deficiency. This study aims examine levels homocysteine pregnant women upon admission for delivery analyze corresponding cord blood samples from their newborn infants a substantial...
To evaluate the outcome of chronic hepatitis B (CHB) in children with or without malignancies.Twenty four (15 boys and 9 girls) malignancies, followed up by pediatric gastroenterology outpatient clinic for CHB between January 2000 December 2013, were enrolled study (Group 1). Group 2 was formed twenty five (11 girls 14 boys) diagnosed malignancies. The data from patients' records compared two groups.Hepatitis e antigen (HBeAg)/antiHBe seroconversion observed 3 patients (12.5%) group 1 15...
Spexin (SPX) is a novel peptide implicated in food intake and satiety. SPX levels are reduced obese patients.This study aimed to compare serum adolescents versus healthy controls assess the associations of metabolic syndrome (metS) antecedents with levels.Eighty consecutive aged 10-18 years 80 peers were enrolled. Anthropometric measurements, pubertal examinations, clinical blood pressure measurements performed. Fasting samples drawn for glucose, insulin, lipids, uric acid, alanine...
Amaç: Dikkat eksikliği ve hiperaktivite bozukluğu (DEHB), pediatrik yaş grubunda yaygın olarak görünen nöropsikiyatrik bir bozukluktur. Nedenine yönelik çok sayıda çalışma yapılmış olsa da etiyoloji tam aydınlatılamamıştır. Biz de DEHB’li hastalarda bazı kan parametrelerini araştırarak, hastalıkla ilgili literatüre katkı yapmayı amaçladık. Gereç Yöntem: Çalışmaya 5-15 arası 91 hasta 116 sağlıklı çocuk dahil edildi. Tüm çocuklardan sayımı, serum demir, total demir bağlama kapasitesi,...
Köker O, Yıldırmak ZY, Genç DB, Kılıçaslan Ö. Thrombotic thrombocytopenic purpura as a rare cause of anemia with thrombocytopenia in childhood: report 2 cases. Turk J Pediatr 2019; 61: 418-423. (TTP) is multisystem disorder characterized by single or recurrent episodes thrombocytopenia, microangiopathic hemolytic and widespread microvascular thrombosis, which causes significant morbidity mortality unless promptly recognized treated. The underlying pathogenesis defect von Willebrand factor...
Malaria, caused by the plasmodium species, is a serious disease that associated with high levels of morbidity and mortality, characterized fever.Here, we present case 10 year-old Syrian-born girl who was admitted to medical center fever attacks accompanied chills, referred our hospital upon detection pancytopenia in an examination continuation complaints proposed follow-up.Splenomegaly detected during physical examination, laboratory test results.The patient diagnosed malaria Plasmodium...
The kidney is a vulnerable organ for acute lymphoblastic leukemia (ALL), by the disease, and various associated clinical pictures. This retrospective study aims to document renal ultrasound abnormalities in children with newly diagnosed ALL as well investigate correlation between findings clinical/laboratory/survival data.All (age <18 years) were included study. An increase size/nephromegaly (NM) or hyperechogenicity (HE) of kidneys at first admission was accepted pathological abnormality....