A5063840511- Metabolism and Genetic Disorders
- Acute Kidney Injury Research
- Coronary Artery Anomalies
- Sepsis Diagnosis and Treatment
- Trauma and Emergency Care Studies
- Muscle and Compartmental Disorders
- Contact Dermatitis and Allergies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Drug-Induced Adverse Reactions
- Cardiovascular Issues in Pregnancy
- Blood Coagulation and Thrombosis Mechanisms
- Growth Hormone and Insulin-like Growth Factors
- Kawasaki Disease and Coronary Complications
- Heparin-Induced Thrombocytopenia and Thrombosis
- Pharmacological Effects and Toxicity Studies
- Inflammasome and immune disorders
- Gout, Hyperuricemia, Uric Acid
- Infections and bacterial resistance
- Blood groups and transfusion
- Hemoglobinopathies and Related Disorders
- Congenital heart defects research
- Apelin-related biomedical research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Sexual Differentiation and Disorders
- Case Reports on Hematomas
Istanbul University
2015-2025
Fatih University
2025
Ankara University
2021-2023
Owl Research Institute
2018
Université Côte d'Azur
2017
Lurie Children's Hospital
2017
Children's Hospital Agia Sophia
2017
National and Kapodistrian University of Athens
2017
Familial Mediterranean fever (FMF) is one of the most frequent genetic diseases encountered in region. We aimed to investigate correlation between mutations and clinical findings 562 patients with FMF. In this retrospective cross-sectional study conducted patients' files 2006, 2013, reverse hybridization assay for MEFV gene was used 12 were screened. Mutation types compared variance analysis. The mean age 6.9 ± 3.4 years (range, 1.8-11.6 years). common symptom (97.3 %). Thirty-four (6.04 %)...
This study addresses the characteristics, kidney replacement therapy (KRT) modalities, and outcomes in children diagnosed with crush syndrome following an earthquake Turkey. To analyze associations of different KRT modalities long-term dialysis dependency length stay (LOS) pediatric intensive care unit (PICU). multicenter, prospective, retrospective cohort was conducted across 20 PICUs Participants included after 2023 Kahramanmaraş earthquake, eligibility criteria age, diagnosis, need for...
ABSTRACT Phenolic antioxidants and curcuminoids are biologically important molecules playing a crucial role in combating reactive species under oxidative stress conditions. In this study, microwave‐assisted extraction (MAE) ultrasound‐assisted (UAE) processes for the of phenolic curcumin from turmeric using an ethanol‐water mixture were optimized modeled with face‐centered composite design response surface methodology. Under optimal conditions, CUPRAC total antioxidant capacity (TAC),...
Objective: 17α-hydroxylase/17,20 lyase deficiency (17OHD) is a rare form of congenital adrenal hyperplasia (CAH), characterized by hypertension and varying degrees ambiguous genitalia delayed puberty.The disease associated with bi-allelic mutations in the CYP17A1 gene located on chromosome 10q24.3.We aimed to present clinical genetic findings follow-up treatment outcomes 17OHD patients.Methods: We evaluated six patients from five families at presentation follow up.Standard deviation score...
Objective: Alpha thalassemia syndromes are caused by mutations on one or more of the four α-globin genes.Mutations could be either commonly deletional non-deletional.As some deletions (3.7 and 4.2) cause α + -thalassemia, (-20.5, MED, THAI, FIL) 0 -thalassemia.The aim this study was to determine alpha in patients with unsolved hypochromic microcytic anemia evaluate types mutations.Material Methods: Two hundred six were evaluated for thalassemia.A venous blood sample 2 mL drawn from each...
<b><i>Background/Aims:</i></b> Enamel-renal syndrome is characterized by nephrocalcinosis, enamel defects, gingival hyperplasia and eruption failures. It has been recently identified that recessive mutations in the <i>FAM20A</i> gene result amelogenesis imperfecta (AI)-gingival fibromatosis. The aim of this research to determine whether AI patients with known <i>FAM20A</i> also have nephrocalcinosis....
Background: Pediatric intensive care units (PICUs), where children with critical illnesses are treated, require considerable manpower and technological infrastructure in order to keep alive free from sequelae. Methods: In this retrospective comparative cohort study, hospital records of patients aged 1 month 18 years who died the study PICU between January 2015 December 2019 were reviewed. Results: A total 2,781 critically ill admitted PICU. The mean±standard deviation age 254 nonsurvivors...
Background: The aim of the study was to evaluate utility lactate, central venous oxygen saturation (ScvO 2 ), and difference in arterial CO partial pressures (delta pCO ) levels their relationship with prognosis critically ill children circulatory failure pediatric intensive care unit (PICU). Subjects Methods: Thirty who were admitted PICU a tertiary university hospital between January 15 November 1, 2020, evaluated this prospective observational study. Lactate levels, ScVO , delta on...
Turner Syndrome (TS) is associated with a high risk of cardiac anomalies and cardiovascular disease. We aimed to evaluate patients TS (n=33) for aortic pathology using thorax magnetic resonance angiography (MRA).Clinical findings, karyotypes, echocardiogram (ECHO) findings MRA results were evaluated. Aortic dimensions measured standard Z scores diameters along size index (ASI) calculated.Mean age the was 13.7±3.4 years. revealed in 10 (30%). CoA (n=4), aberrant right subclavian artery (n=3),...
Abstract Background Multisystem inflammatory syndrome in children (MIS-C) is characterized by persistent fever, abdominal pain, vomiting, diarrhea, rash, conjunctivitis, headaches, and mucocutaneous manifestations it can cause circulatory dysfunction, resulting hypotension, shock, end-organ injury the heart other organs possibly death. In this study, we aimed to analyze clinical spectrum, treatment options outcomes of with MIS-C who were admitted our pediatric intensive care (PICU)....
Adverse reactions to drugs have been defined by the WHO as unwanted effects that occur during use of a drug. The diagnosis drug allergies is not always straightforward due confounding factors such multiple and similarity pertinent symptoms those can be attributed disease processes. In children, are most commonly mistaken for rashes induced viral infections. first step towards detailed history second choosing laboratory test according this history. Skin prick testing preferred immediate type...
Introduction:The choice of anticoagulation in continuous renal replacement therapy (CRRT) is very important for circuit life and bleeding complications.The primary outcome our study was lifespan.Secondary outcomes, we aimed to identify metabolic complications.Methods: This retrospective conducted pediatric intensive care unit between November 2019 March 2021. Results:The included 35 patients, 19 with regional citrate (RCA) 16 heparin (HA).The patient's risk mortality III score similar both...
Background: Many questionnaire surveys around the globe have investigated management of carious lesions in adults, but there is a lack data for children general and primary teeth particular.Aim: The aim present survey undertaken among French GDPs who regularly treat (pediatric dentistry not specialty France) was to investigate decisions approximal occlusal molars.Design: A newly developed sent by mail members Society Pediatric Dentistry (n = 250).The structured assessed restorative...
Botan, E.; Durak, A.; Gün, Gurbanov, Balaban, B.; Kahveci, F.; Özen, H.; Uçmak, Gençay, A. G.; Kendirli, T. Author Information