A5074952742- Childhood Cancer Survivors' Quality of Life
- Hematopoietic Stem Cell Transplantation
- Neuroblastoma Research and Treatments
- Vascular Malformations and Hemangiomas
- Sarcoma Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Blood disorders and treatments
- Blood Coagulation and Thrombosis Mechanisms
- Blood groups and transfusion
- Hepatocellular Carcinoma Treatment and Prognosis
- Venous Thromboembolism Diagnosis and Management
- Lymphoma Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- COVID-19 and healthcare impacts
- Neonatal Health and Biochemistry
- Immunodeficiency and Autoimmune Disorders
- Hemoglobinopathies and Related Disorders
- Erythrocyte Function and Pathophysiology
- Pharmacological Effects and Toxicity Studies
- Iron Metabolism and Disorders
- Mast cells and histamine
- Testicular diseases and treatments
- Chronic Lymphocytic Leukemia Research
- Infective Endocarditis Diagnosis and Management
- COVID-19 Clinical Research Studies
Sağlık Bilimleri Üniversitesi
2018-2025
City Hospital
2021-2023
Memorial Ankara Hospital
2013-2023
Ankara Bilkent City Hospital
2023
Bilkent University
2023
Ministry of Health
2012-2022
University of Health Sciences
2019-2021
Palmetto Hematology Oncology
2016-2021
Children's Hospital
2021
University of Health Sciences Antigua
2021
Primary cardiac tumors are rare in childhood. The most common of these rhabdomyomas. Considering that rhabdomyomas often show spontaneous regression, close follow-up may be sufficient hemodynamically stable cases. However, significant confer a risk morbidity and mortality. Herein, we report newborn infant with multifocal treated everolimus. optimal dose the drug was 0.25 mg 2 times per day, days week. Patients inoperable symptoms candidates for everolimus treatment.
In this study, we retrospectively examined the data of children who underwent allo-HSCT from HLA-matched family donors. We analyzed incidence, etiological factors, clinical characteristics, possible reasons, risk and follow-up neurologic complications. BU-based conditioning regimens were used in most cases (n = 62). The median duration for 89 patients was 20 months (range 1-41 months). Eleven percent transplanted developed one or more neurological symptoms after HSCT with a observation time...
Since the beginning of Syrian civil war, more than 3.5 million Syrians have been under temporary protection status in Turkey. Because beta-thalassemia (BT) is a prevalent disorder Mediterranean countries, we decided to estimate prevalence and make an overview demographic, socioeconomic, medical characteristics, healthcare problems refugee children with BT.Eighteen Turkish Pediatric Hematology Oncology Centers (PHOC) 318 from 235 families participated study. The mean age patients was 8.1 ±...
Endocrine organs are highly susceptible to effects of high-dose chemotherapy. The objective the study was evaluate endocrine and metabolic complications after hematopoietic stem cell transplantation (HSCT) in children.The patients who underwent HSCT our center from April 2010 October 2014 with at least 1 year follow-up were analyzed retrospectively.One-hundred children (M/F:59/41; mean age 8.9±4.8 years, time 3.4±1.2 years) included study. Female hypogonadism most common dysfunction (35.7%),...
Cancer care is progressively became as a significant worldwide challenge. Wars can cause destructions and delays in cancer diagnosis treatment of displaced people. cure rates need to be improved indefensible populations such refugees. In this study, we purposed highlight the clinical peculiarities outcomes refugee children with our hospital. Our purpose was present findings contribute improve health for these children. Seventy one pediatric patients admitted oncology hematology units...
ABSTRACT Paravertebral tumors may interfere with the radiological and clinical features of spinal tuberculosis. We report a case 3-year-old boy tuberculosis who was initially misdiagnosed as having paraspinal tumor. The diagnosis made on basis intraoperative findings confirmed by histopathology. This highlights importance awareness different radiographic tuberculosis, which can mimic malignancy. In order to avoid delayed diagnosis, pediatricians radiologists must be aware other conditions.
WAS is a severe X-linked recessive disorder characterized by microthrombocytopenia, eczema, and immunodeficiency. A six-yr-old boy with diagnosed as B-cell NHL (Stage III) localized in the liver who underwent successful HSCT from HLA-one antigen mismatch sibling donor has been presented here. His conditioning regimen included ATG, busulfan, fludarabine. He received 2.3 × 10(6) /kg CD 34+ stem cells 11 10(8) nucleated at day 0. Neutrophil engraftment was achieved +14 platelet +20. CR for more...
Congenital portosystemic shunts are rare vascular malformations that lead to several complications including liver tumors, pulmonary hypertension, and metabolic encephalopathy. We describe a case of 17-year-old girl with an extrahepatic shunt presenting recurrent syncope episodes mass mimicking hepatocellulary carcinoma.
Emir S, Hacısalihoğlu Ş, Özyörük D, Kaçar Erdem A, Karakuş E. Squamous cell carcinoma associated with Xeroderma pigmentosum: an unusual presentation a tremendously huge mass over the face and paraneoplastic hypercalcemia-hyperleukocytosis. Turk J Pediatr 2017; 59: 711-714. pigmentosum (XP) is rare autosomal recessive disorder that results from genetic defects in DNA repair manifests marked hypersensivity to ultraviolet rays. Children X-P are at high risk of developing skin cancers. On other...
Massive splenic infarction and portal vein thrombosis (PVT) due to chronic myeloid leukemia (CML) is extremely rare. We describe 2 children who were presented with massive PVT in the course of CML. treated splenectomy one medical treatment another whom resolved by cytoreductive treatment, led downsizing spleen or splenectomy. Splenic infarct should be considered CML patients long-lasting severe abdominal pain despite appropriate attempts. Splenectomy spared for persistent symptoms complications.
Infective endocarditis (IE) is an infection of the endocardium and/or heart valves that involves thrombus formation (vegetation). This condition might damage endocardial tissue valves. An indwelling central venous catheter a major risk factor for bacteremia at-risked pediatric populations such as premature infants; children with cancer connective disorders. Herbaspirillum huttiense Gram-negative opportunistic bacillus may cause and pneumonia rarely in this fragile population. Herein we...
Abstract There are few studies evaluating the use of I g M ‐enriched IVIG ( P entaglobin ® ) in HSCT recipients. This study aimed to compare efficacy prophylactic versus within first 100 days after allogeneic . We performed a prospective, randomized patients The dose or was given before conditioning regimen and transplant on day +1, +8, +15, +22. And then, it if G level below 400 mg/dL. Twenty‐seven group 32 were included study. no significant differences duration neutropenia,...
Primary immune deficiencies are a group of heterogenous genetic disorders characterized by frequent infections, autoimmunity and malignancy. In this study, we aimed to evaluate clinical characteristics, outcomes children with malignancy developed on background primary immunodeficiency compare survival rates patients between malignant lymphoma without from tertiary oncology center in developing country. A total 23 were evaluated retrospectively. 26 malignancies (first or second) determined....
Constitutional mismatch repair deficiency (CMMRD) syndrome is a rare childhood cancer predisposition resulting from biallelic germline mutations of (MMR) genes. CMMRD characterised by early onset malignancies in children.Here we present affected children consanguinous parents diagnosed with due to bi-allelic MSH 6 gene café au lait spots and multiple family cancers Turkey reported cases associated mutation English literature. Hence, reviewed literature 1990 2020 using Pub-Med database....
Hepatocellular adenomas are a benign, focal, hepatic neoplasm that have been divided into four subtypes according to the genetic and pathological features. The β-catenin activated subtype accounts for 10-15% of all hepatocellular specific magnetic resonance imaging features defined different subtypes. current study aimed report well differentiated carcinoma developed on basis in child. In this case, atypical diffuse steatosis was determined lesion. literature, steatosis, which is as feature...
Hepatitis-associated aplastic anemia (HAA) is a form of acquired (AA) in which bone marrow failure develops after an acute attack hepatitis. Bone leading to AA generally severe cases HAA and fatal if left untreated. This retrospective multicenter study investigated clinical laboratory characteristics, possible causes, treatment, outcome children. Twenty patients from 8 centers were included the study. Aspartate aminotransferase alanine <3 5×upper limit normal (ULN) 2 patients, <5 10×ULN...
Introduction: Mastocytosis is a rare and heterogenous disease, in children it generally limited to the skin tends regress spontaneously adolescence. Aim: In this study, demographic, clinical, laboratory characteristics of pediatric patients with mastocytosis, also coexisting diseases were investigated. Results: A total 61 included study. The male-to-female ratio was 2.2, median age 2 years (range, 0.25 19 y), follow-up period 2.0 y). Types clinical presentation at diagnosis consisted mainly...
Upper extremity deep vein thrombosis (UEDVT) is extremely rare in children and adolescents. Paget - Schroetter Syndrome (PSS) the primary, spontaneous of subclavian venous (SV) axillary tract. Herein, we report on PSS two who did regular body building exercises. 16-year-old male patients admitted with complaints swelling, coldness pain right upper extremity. Their recent history disclosed that they have been doing advanced exercises for last year. Physical examination revealed a difference 4...
Abstract Background The published experience concerning autologous peripheral blood stem cell collection in children is very limited. Methods data of pediatric patients who underwent mobilization and apheresis between January 2011 April 2020 were analyzed retrospectively. Results We studied retrospectively 64 procedures 48 (34 males, 14 females), mean age 7.31 ± 5.38 (range, 1.5–19.7) years, the underlying disease was mostly neuroblastoma (NBL). body weight 21 (43.75%) 15 kg or less....