A5086731452- Childhood Cancer Survivors' Quality of Life
- Platelet Disorders and Treatments
- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Autoimmune and Inflammatory Disorders Research
- Epigenetics and DNA Methylation
- Cancer-related gene regulation
- RNA modifications and cancer
- Immunodeficiency and Autoimmune Disorders
- Cytomegalovirus and herpesvirus research
- Telomeres, Telomerase, and Senescence
- RNA regulation and disease
- Adolescent and Pediatric Healthcare
- Ethics and Legal Issues in Pediatric Healthcare
- Infectious Encephalopathies and Encephalitis
- Helicobacter pylori-related gastroenterology studies
- Chronic Lymphocytic Leukemia Research
- Herbal Medicine Research Studies
- Healthcare and Venom Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Blood groups and transfusion
- Burkholderia infections and melioidosis
- Kawasaki Disease and Coronary Complications
- Erythrocyte Function and Pathophysiology
- Heparin-Induced Thrombocytopenia and Thrombosis
Sağlık Bilimleri Üniversitesi
2023-2025
Adana Numune Eğitim ve Araştırma Hastanesi
2022
Cukurova University
2017-2022
Acute lymphoblastic leukemia (ALL) and other hematological malignancies are the most common cancers in children, with chemotherapy and/or radiotherapy as primary treatment options. These treatments, however, may have long-term effects on ovarian function fertility female survivors. This study aims to evaluate reserve survivors of childhood by assessing hormonal markers follicle count. cross-sectional included 30 acute leukemia, non-Hodgkin lymphoma (NHL), Hodgkin (HL) who completed between...
Since the beginning of Syrian civil war, more than 3.5 million Syrians have been under temporary protection status in Turkey. Because beta-thalassemia (BT) is a prevalent disorder Mediterranean countries, we decided to estimate prevalence and make an overview demographic, socioeconomic, medical characteristics, healthcare problems refugee children with BT.Eighteen Turkish Pediatric Hematology Oncology Centers (PHOC) 318 from 235 families participated study. The mean age patients was 8.1 ±...
Allergic reactions from insect bites are mostly observed with bee stings. Bee sting can be classified into 3 main headings: local, systemic, and rare reactions. Vascular thrombosis is considered both in systemic The wild venom induces the secretion of many inflammatory mediators, including histamine, phospholipase A1, thromboxane, leading to vasoconstriction thrombosis. Inflammatory cytokines also cause endothelial injury deterioration microcirculation. In literature, have been reported...
We aimed to investigate the indications for Carbohydrate antigen 19-9 (CA 19-9), carbohydrate 125 (CA-125), 15-3 (CA15-3) and carcinoembryogenic (CEA) tumor biomarkers, less commonly used in children, their association with patients diagnosed childhood cancers. The study include aged 0-18 who had CA 19-9, CA-125, CEA biomarker assessments at Adana City Training Research Hospital (ACTRH) between 01.11.2022 01.11.2023. values were recorded from routinely collected serum/blood samples of...
Summary Pyruvate kinase (PK) is a key enzyme of anaerobic glycolysis. The genetic heterogeneity PK deficiency (PKD) high, and over 400 unique variants have been identified. Twenty‐nine patients who had diagnosed as PKD genetically in seven distinct paediatric haematology departments were evaluated. Fifteen 23 (65.2%) low levels. PK:hexokinase ratio 100% sensitivity for diagnosis, superior to assay. Two novel intronic (c.695‐1G>A c.694+43C>T) described. should be suspected with chronic...
Aim Coeliac disease (CD) is an autoimmune enteropathy that develops upon ingestion of food containing gluten. The established link between ABO blood groups and numerous infectious non‐infectious illnesses prompted this investigation into group distribution its relationship with dietary compliance among children diagnosed CD. Methods In retrospective study, patients CD who were followed for ≥1 year at the paediatric gastroenterology outpatient clinic our hospital evaluated. History, physical...
Introduction and importance: Dyskeratosis congenita (DC) is a rare multisystem disorder primarily characterized by bone marrow failure due to telomere shortening. Typical clinical features include oral leukoplakia, skin hyperpigmentation, nail dystrophy, along with an increased risk of malignancies. Hoyeraal–Hreidarsson syndrome (HH), severe variant DC, associated profound neurological immunological complications, emphasizing the importance early diagnosis genetic evaluation guide...
Diamond–Blackfan anemia is a rare congenital disorder characterized by erythroid hypoplasia and associated with mutations in ribosomal protein genes. This case report describes novel variant the RPS26 gene, which, to our knowledge, has not been previously documented. Reporting this adds understanding of anemia's genetic diversity phenotypic manifestations. A 16-month-old Turkish girl presented pallor macrocytosis. There was no familial history anemia. Hemoglobin electrophoresis showed...
Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency disorder that characterized by triad of microthrombocytopenia, severe immunodeficiency, and eczema. We report the case 7-year-old male patient with chronic thrombocytopenia was diagnosed as WAS after dilatation ascending aorta noticed. rare, it disease requires high suspicion for diagnosis. recommend periodic echocardiography magnetic resonance imaging examinations to evaluate aortic aneurysms in children surgical...
Purpose: Some patients with cancer use herbal therapy as an adjunct while receiving conventional treatments. Beta-glucans have direct cytotoxic effects on cells well stimulatory the immune system. In this study, a nutritional supplement containing 1,3-1,6 beta-glucan obtained from baker's yeast (Saccharomyces cerevisiae) was used by diagnosed sarcoma, and study aimed to retrospectively evaluate effect of incidence neutropenic fever (NF) survival rates. 
 Materials Methods: Among sarcoma...
Enfekte hayvanlardan ve ürünlerinden insanlara bulaşan bruselloz, ülkemizde tüm dünyada halen yaygın olarak görülen zoonotik bir enfeksiyondur. Çalışmamızda tek merkeze başvuran pediatrik bruselloz vakalarının demografik özellikleri, hematolojik laboratuvar anormalliklerinin değerlendirilmesi amaçlanmıştır. Bu çalışmada Haziran 2020 ile 2021 tarihleri arasında nedeni takip edilen 47 çocuk hasta retrospektif incelenmiştir. Çalışmamızdaki hastanın 23 (%48.9)’ü erkek, 24 (%51.1)’ü kızdı yaş...
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by caused the formation of antibodies against platelets. Mucosa-associated invariant T cells (MAIT), a subset unconventional present in blood and mucosa, are activated MR-1-mediated manner, respond to certain infections cytokines produce various effector cytokines. In this study, changes MAIT were investigated pediatric ITP patients who received did not receive Eltrombopag. Twenty healthy volunteers (n:20), 60 untreated, 16...
Purpose: In this study, it was aimed to determine the atypical localizations of extramedullary hematopoiesis (EMH) in patients with hemolytic anemia, most whom were diagnosed hemoglobinopathy and are followed our region.
 Materials Methods: The files imaging examinations anemia who up Pediatric Hematology Clinic hospital between 01.07.2020-28.02.2022 retrospectively scanned. Patients had lesions by due their complaints or other reasons evaluated. Some over age 18 cases mostly detected...
At the end of 2019, newly detected severe acute respiratory syndrome-coronavirus (COVID)-2 in China spread rapidly and caused a global epidemic. It has been observed that virus, which is cause COVID-2019 can failure, later causes hyperinflammatory picture clinical similar to Kawasaki disease. Fever, cardiac involvement rash are most common findings this picture, called multisystem inflammatory syndrome (MIS-C). Although its pathophysiology not fully known yet, thought be post-infection...