- Lichen and fungal ecology
- Dental Research and COVID-19
- Dental Radiography and Imaging
- Oral Health Pathology and Treatment
- Dental materials and restorations
- Dental Anxiety and Anesthesia Techniques
- Oral microbiology and periodontitis research
- Botany and Plant Ecology Studies
- Medicinal plant effects and applications
- Dental Implant Techniques and Outcomes
- Semiconductor materials and devices
- Dental Health and Care Utilization
- Endodontics and Root Canal Treatments
- Orthodontics and Dentofacial Orthopedics
- Periodontal Regeneration and Treatments
- Dental Education, Practice, Research
- Diamond and Carbon-based Materials Research
- Pediatric health and respiratory diseases
- Bryophyte Studies and Records
- Medical and Biological Sciences
- Cancer Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Innovations in Medical Education
- Metal and Thin Film Mechanics
- Phytochemicals and Antioxidant Activities
Ovidius University
2015-2024
Titu Maiorescu University
2021
Dimitrie Cantemir University
2021
Dental implants in dental agenesis are an effective and sustainable solution for replacing missing teeth patients who have not developed some or more permanently. is a condition which one do form erupt normally. In the case of agenesis, can be used to replace teeth, giving patient aesthetic smile necessary functionality during chewing speaking. Here important discussions about agency: Individual evaluation: Each with will evaluated individually by dentist. Issues such as number position bone...
CBCT (Cone Beam Computed Tomography) plays a crucial role in implantology, offering significant advantages over traditional two-dimensional imaging techniques, such as X-rays. Here are some of the important benefits implantology. Precise three-dimensional imaging: provides high-resolution images patient's oral and maxillofacial region. This allows comprehensive assessment anatomical structures, including bone volume, quality, density. evaluation these factors is for successful implant...
Lichens represent an important resource for common traditional medicines due to their numerous metabolites that can exert diverse pharmacological activities including anticancer effects. To find new compounds with fewer side effects and low tumor resistance, a bioprospective study of Usnea barbata (L.) F.H. Wigg. (U. barbata), lichen from the Călimani Mountains (Suceava county, Romania) was performed. The aim this research investigate potential, morphologic changes, wound healing property,...
Phenolic compounds represent an essential bioactive metabolites group with numerous pharmaceutical applications. Our study aims to identify and quantify phenolic constituents of various liquid dry extracts Usnea barbata (L.) Weber ex F.H. Wigg (U. barbata) from Calimani Mountains, Romania, investigate their bioactivities. The in acetone, 96% ethanol, water the same dried lichen/solvent ratio (w/v) were obtained through two conventional techniques: maceration (mUBA, mUBE, mUBW) Soxhlet...
Nowadays, numerous biomedical studies performed on natural compounds and plant extracts aim to obtain highly selective pharmacological activities without unwanted toxic effects. In the big world of medicinal plants, Usnea barbata (L) F.H. Wigg (U. barbata) usnic acid (UA) are well-known for their therapeutical properties. One most studied properties is cytotoxicity various tumor cells. This work aims evaluate cytotoxic potential normal blood Three dry U. in solvents: ethyl acetate (UBEA),...
Usnea genus (Parmeliaceae, lichenized Ascomycetes) is a potent phytomedicine, due to phenolic secondary metabolites, with various pharmacological effects. Therefore, our study aimed explore the antioxidant, cytotoxic, and rheological properties of barbata (L.) Weber ex F.H. Wigg (U. barbata) extract in canola oil (UBO) compared cold-pressed seed (CNO), as green solvent used for lichen extraction, which has phytoconstituents. The antiradical activity (AA) UBO CNO was investigated using UV-Vis...
Medical research explores plant extracts' properties to obtain potential anticancer drugs. The present study aims formulate, develop, and characterize the bioadhesive oral films containing Usnea barbata (L.) dry ethanol extract (F-UBE-HPC) investigate their for possible use in cancer therapy. physicochemical morphological of were analyzed through Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), Atomic Force Microscopy (AFM), thermogravimetric analysis (TG),...
Oral squamous cell carcinoma (OSCC) is the most frequent oral malignancy, with a high death rate and an inadequate response to conventional chemotherapeutic drugs. Medical research explores plant extracts' properties obtain potential nanomaterial-based anticancer The present study aims formulate, develop, characterize mucoadhesive films loaded Usnea barbata (L.) dry acetone extract (F-UBA) investigate their for possible use in cancer therapy. U. (UBA) was solubilized ethanol: isopropanol...
Lichens represent a significant source of antioxidants due to numerous metabolites that can reduce free radicals.
This study aims to complete our research on Usnea barbata (L.) Weber ex F.H. Wigg (U. barbata) from the Călimani Mountains, Romania, with an elemental analysis and explore its antibacterial antifungal potential. Thus, we analyzed twenty-three metals (Ca, Fe, Mg, Mn, Zn, Al, Ag, Ba, Co, Cr, Cu, Li, Ni, Tl, V, Mo, Pd, Pt, Sb, As, Pb, Cd, Hg) in dried U. lichen (dUB) by inductively coupled plasma mass spectrometry (ICP-MS). For second study, performed extraction five different solvents (ethyl...
Usnea lichens are known for their beneficial pharmacological effects with potential applications in oral medicine. This study aims to investigate the extract of barbata (L.) Weber ex F.H. Wigg from Călimani Mountains canola oil as an pharmaceutical formulation. In present work, bioadhesive films (F-UBO) U. (UBO) were formulated, characterized, and evaluated, evidencing potential. The UBO-loaded analyzed using standard methods regarding physicochemical pharmacotechnical characteristics verify...
The secondary metabolites of lichens have proven to be promising sources anticancer drugs; one the most important these is usnic acid, which a phenolic compound with dibenzofuran structure that responsible for numerous biological actions genus Usnea. As result, in this study, we related metabolite. aim present study evaluation cytotoxic activity Usnea barbata (L.) F. H. Wigg dry acetone extract (UBE). In advance, acid content was determined various extracts Wigg: liquid were found water,...
Lysimachia nummularia L. is a perennial herbaceous plant rich in bioactive compounds, which can be utilized for medicinal purposes. The present work aims to analyze the phenolic compounds from different parts of using HPLC technique: Lysimachiae radix (the root part), herba aerial flores (flowers). In order determine extraction three categories vegetable products was performed with ethanol 70% (v/v) methods: (i) Soxhlet extraction, (ii) maceration and (iii) ultrasonic-assisted extraction....
Usnea barbata (L.) Weber ex F.H. Wigg (U. barbata) is a medicinal representative of the lichens from genus (Parmeliaceae, lichenized Ascomycetes), containing bioactive secondary metabolites. The aim this study comparative analysis between two separated parts thallus layers: medulla–cortex (mcUB) and central cord (ccUB) whole dried U. (dUB). These three samples were examined regarding color differences. morphology was through fluorescent microscopy (FM) scanning electron (SEM). mineral...
The present study was carried out to develop an experimental endodontic irrigant solution based on plant extracts obtained from Epilobium parviflorum Schreb. that largely replenish the properties of usual antiseptics used in dentistry. Background: This investigated phytochemical contents and their potential antibacterial activity. Methods: Identification quantification biologically active compounds were made by UV field photo spectrometry, adapting Folin-Ciocalteu test method. Antibacterial...
The oral cavity’s common pathologies are tooth decay, periodontal disease, and cancer; squamous cell carcinoma (OSCC) is the most frequent malignancy, with a high mortality rate. Our study aims to formulate, develop, characterize, pharmacologically investigate mucoadhesive patches (F-UBE-HPMC) loaded Usnea barbata (L.) F.H. Wigg dry ethanol extract (UBE), using HPMC K100 as film-forming polymer. Each patch contains 312 µg UBE, total phenolic content (TPC) of 178.849 33.924 usnic acid....
Since loading is increasingly believed to be a determining factor in the treatment outcome with oral implants, there need expand knowledge related biomechanics of implants. The aim this study gain insight distribution and magnitude occlusal forces on implants carrying fixed prostheses. This done by vivo quantification qualification these forces, which implies that not only load but also its type (axial force). Occlusal supporting were quantified qualified during controlled application 850 N...
This study tries to identify the influence of new coronavirus pandemic on dental education by assessing students’ perception and their didactic performance regarding virtual traditional lectures. The final academic performances students from different years at Faculty Dental Medicine who participated in undergraduate courses through two lecturing modes (traditional virtual) were compared. same evaluated terms preference between techniques. There was a statistically significant difference...
The intraosseous implants are the most used dental implants. development of new classes biomaterials determined apparition Trinia, a Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) reinforced polymer, for core in non-metallic prosthetic restorations, including superstructure. aim study was to present obtained results use Trinia polymer as on abutments Bicon 35 patients were selected, 19 females and 16 males, aged between 31 60 years. After 18 months monitoring, we ascertained...
Worldwide, with the economic growth malocclusions recorded a significant increase, which has led to their ranking as third most widespread oral health problem after dental caries and periodontal disease being considered priority among problems by World Health Organization. The aim of this study consisted an evaluation socio-environmental factors associated malocclusion. clinical characteristics 125 children (from 5 12 years old, no previous orthodontic treatment), were evaluated means visual...
The objective of this study is to determine prevalent behaviors and knowledge oral hygiene on the late adolescents. Only individuals in stage adolescence, specifically between ages 18 24, that were students from "Ovidius" University Constanta chosen. involvement was optional. A printed questionnaire provided for them complete. total 50 participants took part study, consisting 26% (n=13) males 74% (n=37) females. When asked about their toothbrush preference, 50% (n=25) indicated using just...
The aim of this study was represented by the identification type relation between bruxism sleep index and global quality life.
Prevention and early management of oro-dental complications in cancer therapy will improve oral function quality life reduce morbidity cost care. Oral hygiene was strongly recommended before treatment, preventive measures care should be continued during after treatment. The aim this study to evaluate the level patients' knowledge about importance optimal dental status order minimize occurrence adverse effects chemotherapy treatment an oncology clinic Romania. Material methods A four-part...