A5002384150- Natural Antidiabetic Agents Studies
- Natural Compounds in Disease Treatment
- Natural product bioactivities and synthesis
- Phytochemicals and Antioxidant Activities
- Bioactive natural compounds
- Sesquiterpenes and Asteraceae Studies
- Lipid metabolism and disorders
- Aquatic Ecosystems and Phytoplankton Dynamics
- Sperm and Testicular Function
- Psidium guajava Extracts and Applications
- Phytochemistry and Biological Activities
- Food Science and Nutritional Studies
- Bee Products Chemical Analysis
- Sexual function and dysfunction studies
- Testicular diseases and treatments
- Metabolomics and Mass Spectrometry Studies
- Plant Toxicity and Pharmacological Properties
- Algal biology and biofuel production
University of Zululand
2015-2025
Despite the many current cholesterol-lowering drugs on market, persistent surge of hypercholesterolemic-related complications ignites a fascinating search for discovery novel therapeutics. This study aimed at investigating anti-hypercholesterolemic effect Bauhinia bowkeri extracts. The plant material was sequentially extracted with n-hexane, dichloromethane (DCM), and 70% ethanol. phytochemical constituents extracts were analyzed through GC-MS antioxidant activity screened against wide range...
Control of postprandial hyperglycemia is crucial in the management diabetes mellitus. Despite use current hypoglycemic drugs, incidence and related diseases continue to increase. This study aimed at evaluating vivo antihyperglycemic activity methyl-3β-hydroxylanosta-9,24-dien-21-oate (RA-3), a lanosteryl triterpene isolated, characterized from Protorhus longifolia stem bark. Spectroscopic data analysis was used establish verify structure triterpene. The evaluated an STZ-induced rat model....
Cyanobacteria in recent times have been touted to be a suitable source for the discovery of novel compounds, including antioxidants and antibiotics, due their large arsenal metabolites. This study presents vitro antioxidant silico evaluation Cylindrospermum alatosporum NR125682 Loriellopsis cavenicola NR117881, isolated from freshwater ponds around campus University Zululand, South Africa. The isolates were confirmed using 16S rRNA. Various crude extracts microbes prepared through sequential...
Background. This study evaluated in vitro antidiabetic and antioxidant properties of different extracts (n-hexane, dichloromethane (DCM), 70% ethanol) honeybush tea (Cyclopia genistoides). Over a period 28 days, antiprotein glycation was some indicators (α-amylase, α-glucosidase, pancreatic lipase inhibitory effects) activities (DPPH, ABTS, hydroxyl radical, metal ion chelating, reducing power) for each the crude were also investigated. The results showed that all tested C. genistoides had...
The traditional use of medicinal plants in the management sexual dysfunctions has a long history. This study investigated testicular dysfunction ameliorative effect methanolic roots extracts Maytenus procumbens and Ozoroa paniculosa butanol-induced rat model. rats respective experimental groups were orally administered with extract at 50 250 mg/kg bw, daily for 28 days. cytotoxicity was evaluated against HEK293, MCF-7, HT29 cell lines. exhibited moderate (LC 30.3–330.2 μ g/mL) to weak...
Background: Diabetes mellitus has been identified as one of the global cause disability and death. Objectives: The study aim to investigate in-vitro antidibetic antioxidant activities methanolic extract Encephalartos ferox leaves. Materials Methods: plant was screened for its Phytochemical composition. material extracted with methanol (in-vitro) activity using ABTS DPPH assays. potential antidiabetic evaluated against some carbohydrates (α- amylase α-glucosidase) lipid (pancreatic lipase)...
Erectile dysfunction (ED) due to diabetes mellitus remains difficult treat despite advances in pharmacotherapeutic approaches the field. Therefore, this study investigated erectogenic effect of methanolic extract Maytenus procumbens on type 2 rats. The fructose-streptozotocin model was used induce diabetes-linked ED male sexually active rats were randomly divided into two major groups; normal group and high fructose fed for 120 days. After days, given a single intraperitoneal injection...
Erectile dysfunction (ED) due to diabetes mellitus remains difficult treat despite advances in pharmacotherapeutic approaches the field. Therefore, this study investigated erectogenic effect of methanolic extract Maytenus procumbens roots on type 2 rats. The fructose-streptozotocin model was used induce diabetes-linked ED male sexually active Sprague Dawley rats were randomly divided into two major groups; normal group and high fructose fed for 120 days. After days, given a single...
Reactive oxygen species are implicated in multiple pathological conditions including erectile dysfunction. This study evaluated the vitro and vivo antioxidant potential of methanolic extracts Inula glomerata Salacia kraussii. The plant materials were pulverized extracted with methanol. phytochemical analysis, ability crude to scavenge free radicals (ABTS, DPPH, NO.) as well total phenolic flavonoid contents was investigated. In vivo, potentials (50/250 mg/kg body weight) determined an...