A5052404178- Natural Antidiabetic Agents Studies
- Phytochemical and Pharmacological Studies
- Natural product bioactivities and synthesis
- Chromium effects and bioremediation
- Marine Sponges and Natural Products
- Plant Toxicity and Pharmacological Properties
- Lipid metabolism and biosynthesis
- Aquatic Ecosystems and Phytoplankton Dynamics
- African Botany and Ecology Studies
- Enzyme-mediated dye degradation
- Sesquiterpenes and Asteraceae Studies
- Herbal Medicine Research Studies
- Cholinesterase and Neurodegenerative Diseases
- Phytochemistry and Biological Activities
- Alzheimer's disease research and treatments
- Pharmaceutical and Antibiotic Environmental Impacts
- Phytochemicals and Antioxidant Activities
- Food Science and Nutritional Studies
- Plant biochemistry and biosynthesis
- Microbial Metabolism and Applications
- Essential Oils and Antimicrobial Activity
University of Zululand
2021-2025
Despite the many current cholesterol-lowering drugs on market, persistent surge of hypercholesterolemic-related complications ignites a fascinating search for discovery novel therapeutics. This study aimed at investigating anti-hypercholesterolemic effect Bauhinia bowkeri extracts. The plant material was sequentially extracted with n-hexane, dichloromethane (DCM), and 70% ethanol. phytochemical constituents extracts were analyzed through GC-MS antioxidant activity screened against wide range...
The challenges of antimicrobial resistance (AMR) to human health have pushed for the discovery a new antibiotics agent from natural products. Cyanobacteria are oxygen-producing photosynthetic prokaryotes found in variety water habitats. Secondary metabolites produced by cyanobacteria survive extreme environmental stress factors, including microbial competition. This study presents antibacterial activity and mechanism crude extracts Cylindrospermum alatosporum NR125682 (A) Loriellopsis...
Synthetic and untreated dyes discharged in wastewater effluents are a threat to an ecosystem. This study investigated dye degradation detoxification efficiency of crude lignin peroxidase separately obtained from the cultures Escherichia coli (LR0250096.1) Pseudomonas aeruginosa (CP031449.2). The ability degrade Malachite Green (MG), Remazol Brilliant Blue R (RBBR), Congo Red (CR), Azure B (AZ) was evaluated at different operating conditions (enzyme, dye, hydrogen peroxide concentrations; pH;...
Alzheimer's disease (AD) is the most common form of dementia and constitutes fifth leading cause mortality across globe. Available treatment modalities drugs have abysmally failed to curtail AD. This study evaluated mitigation Aβ aggregation anti-cholinesterase activities with crude extracts Ptaeroxylon obliquum Bauhinia bowkeri. Computational studies abundant phytochemicals from both plants proteins were investigated. The phytochemical composition different (hexane, DCM, ethanol) analyzed...
This study investigated anti-viral, antioxidant activity and anti-pyretic of crude extract from Artemisia afra, absinthium Pittiosporum viridflorum leaves. The extracts were prepared by maceration using aqueous, methanol dichloromethane respectively. Antiviral studies evaluated with influenza virus Fluorescence based -Neuraminidase inhibitors. Antioxidant activities determined DPPH, Nitric oxide, hydroxyl super oxide anion radicals’ Anti-pyretic rats yeast induced pyrexia. Total phenol,...
Triterpenoids have been identified as potential novel lipid‐lowering drugs for the treatment of hypertriglyceridemia. This study investigated antilipogenic and/or antilipolytic effects two triterpenoids (ARM‐2 and RA‐5) isolated from stem bark Protorhus longifolia (Benrh.) Engl. Employing a combination in silico predictions vitro assays, interactions between these key proteins involved lipogenesis lipolysis were investigated. In molecular docking analysis predicted favourable binding...
Parkia biglobosa (PB) is among the various underexploited nutritious plants. A comparative study was conducted on effect processing PB has amino and fatty acid composition. Fermented (FPB), defatted (DPB), protein isolates (PI) samples were prepared from seeds using methods, evaluated standard analytical protocols. The PI showed highest significant total non-essential acids, essential conditionally acids when compared with FPB DPB. In addition, (p < 0.05) neutral basic aromatic lowest...
Reactive oxygen species are implicated in multiple pathological conditions including erectile dysfunction. This study evaluated the vitro and vivo antioxidant potential of methanolic extracts Inula glomerata Salacia kraussii. The plant materials were pulverized extracted with methanol. phytochemical analysis, ability crude to scavenge free radicals (ABTS, DPPH, NO.) as well total phenolic flavonoid contents was investigated. In vivo, potentials (50/250 mg/kg body weight) determined an...