- Chalcogenide Semiconductor Thin Films
- Quantum Dots Synthesis And Properties
- Semiconductor materials and devices
- Semiconductor Quantum Structures and Devices
- Plant Pathogens and Fungal Diseases
- Mosquito-borne diseases and control
- Plant Pathogenic Bacteria Studies
- Advanced Semiconductor Detectors and Materials
- Semiconductor materials and interfaces
- Viral Infections and Vectors
- Plant Virus Research Studies
- Viral gastroenteritis research and epidemiology
- Plant Disease Resistance and Genetics
- Ferroelectric and Piezoelectric Materials
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Marine and fisheries research
- Copper Interconnects and Reliability
- Cardiac Arrest and Resuscitation
- Plant Pathogens and Resistance
- Crystallography and molecular interactions
- GaN-based semiconductor devices and materials
- Phytoplasmas and Hemiptera pathogens
- Electronic and Structural Properties of Oxides
- Insect symbiosis and bacterial influences
Marine Scotland
2004-2024
University Hospitals Plymouth NHS Trust
2021-2024
Plant & Food Research
2013-2023
Ollscoil na Gaillimhe – University of Galway
2020
Sheffield Teaching Hospitals NHS Foundation Trust
2015-2019
Chapel Allerton Hospital
2011-2018
Health Service Executive
2010-2017
Central Statistics Office
2016
Cardiff University
2014
Leeds Teaching Hospitals NHS Trust
2012
The aim of the EuReCa ONE study was to determine incidence, process, and outcome for out hospital cardiac arrest (OHCA) throughout Europe.This an international, prospective, multi-centre one-month study. Patients who suffered OHCA during October 2014 were attended and/or treated by Emergency Medical Service (EMS) eligible inclusion in Data extracted from national, regional or local registries.Data on 10,682 confirmed OHCAs 248 regions 27 countries, covering estimated population 174 million....
Viruses of the family Flaviviridae are important human and animal pathogens. Among them, Flaviviruses dengue (DENV) West Nile (WNV) cause regular outbreaks with fatal outcomes. The RNA-dependent RNA polymerase (RdRp) activity non-structural protein 5 (NS5) is a key for viral replication. In this study, crystal structures enzymatically active inactive WNV RdRp domains were determined at 3.0- 2.35-A resolution, respectively. shown to be mostly similar RdRps members hepatitis C bovine diarrhea...
The effect of post-oxide-growth fluorine incorporation in gate dielectrics is reported. Fluorine was introduced through ion implantation into polysilicon and diffused the oxide, as indicated by SIMS measurements. No great decrease breakdown field observed, although a charge-to-breakdown seen. Interface characteristics also improved with medium to high doses fluoride. High were found grow additional oxide. NMOS FETs showed increased immunity hot-electron-induced stress. These results are...
Dengue virus nonstructural protein 5 (NS5) is a large multifunctional with central role in viral replication. We previously identified two nuclear localization sequences (NLSs) within the region of dengue type‐2 (DENV‐2) NS5 (‘aNLS’ and ‘bNLS’) that are recognized by importin α/β β1 transporters, respectively. Here, we demonstrate importance kinetics to production for first time show aNLS responsible. Site‐specific mutations bipartite‐type or bNLS were introduced into reporter plasmid...
ABSTRACT The protein NS3 of Dengue virus type 2 (DEN-2) is the second largest nonstructural specified by and known to possess multiple enzymatic activities, including a serine proteinase located in N-terminal region an NTPase-helicase remaining 70% protein. latter has seven conserved helicase motifs found all members family Flaviviridae . DEN-2 lacking was synthesized as fusion with glutathione S- transferase Escherichia coli. effects 10 mutations on ATPase RNA activity were examined....
n-type silicon-doped epitaxial layers of gallium arsenide grown by molecular-beam epitaxy (MBE) or metal-organo chemical vapor deposition (MOCVD) have been investigated measurements the Hall effect and strengths localized vibrational modes (LVM) silicon impurities using both Fourier transform absorption spectroscopy Raman scattering at an excitation energy 3 eV close to E1 band gap. Lines from Si(Ga) donors, Si(As) acceptors, Si(Ga)-Si(As) pairs, Si-X, a complex with native defect, were...
A genomic-length cDNA clone corresponding to the RNA of dengue virus type 2 (DEN-2) New Guinea C strain (NGC) was constructed in a low copy number vector. The cloned stably propagated Escherichia coil and designated pDVWS501. transcripts produced vitro from using T7 polymerase yielded infectious (MON501) upon electroporation into BHK-21 cells. When compared with parental NGC virus, MON501 replicated similar levels Aedes albopictus C6/36 cells showed neurovirulence suckling mice. In contrast,...
MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 276:237-248 (2004) - doi:10.3354/meps276237 Temporal and spatial variation in reproductive investment of Atlantic cod Gadus morhua northern North Sea Scottish west coast Michio Yoneda1,2,*, Peter J. Wright1 1Fisheries Research Services Laboratory, PO Box 101 Victoria Road, Aberdeen AB11 9DB, UK 2Present...
Fifteen proteins were detected in Vero cells infected by dengue type 2 (DEN-2) virus that not observed mock-infected cells, namely P98, p82, P67, GP60, gp54, GP46, p30, p28, gp22, GP20, p18, gp16, p15, p14 and gp13. With the exceptions of gp54 gp13, polypeptides corresponding to those listed above also DEN-2 virus-infected Aedes albopictus C6/36 cells. Pulse-chase labelling experiments suggested a possible precursor-product relationship between p30 gp22 GP20. Peptide mapping...
Although all established functions of dengue virus NS5 (nonstructural protein 5) occur in the cytoplasm, its nuclear localization, mediated by dual localization sequences, is essential for replication. Here, we have determined mechanism which can localize cytoplasm to perform role replication, establishing first time that it able be exported from nucleus exportin CRM1 and hence shuttle between cytoplasm. We define export sequence responsible residues 327–343 confirm interaction pulldown...
Several biological and environmental factors have direct or indirect influence on maturation, fecundity egg viability of marine fishes.The relationships observed between these reproductive characteristics specific and/or indices may provide alternative methods estimating annual variations in the potential fish stocks absence data, represent a more rapid less costly method monitoring production.The utility to serve as proxies for production will depend predictive power relationships, effort...
The severity of dengue virus infection ranges from mild fever to hemorrhagic and shock syndrome. association disease with replication in monocyte-derived macrophages (MDMs) was examined for type 2 (DEN-2) isolates Asia or America. Additionally, we constructed DEN-2 recombinant viruses substitutions at residue 390 the envelope glycoprotein (E390) because this is linked region origin. Comparisons yields 3 failed show a correlation clinical disease. However, American strain did not replicate as...
MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 381:297-310 (2009) - DOI: https://doi.org/10.3354/meps07893 Habitat preferences and interannual variability in occurrence of harbour porpoise Phocoena phocoena off northwest Scotland Francesca Marubini1,*, Alessandro Gimona2, Peter G. H. Evans3, J. Wright4, Graham Pierce1,5 1School Biological Sciences...