A5088651962- HIV-related health complications and treatments
- Liver Disease Diagnosis and Treatment
- Food Security and Health in Diverse Populations
- Diet and metabolism studies
- HIV/AIDS Research and Interventions
- Hepatitis C virus research
- Child Nutrition and Feeding Issues
- Child Nutrition and Water Access
- HIV, Drug Use, Sexual Risk
- COVID-19 and Mental Health
- Alcohol Consumption and Health Effects
- Dietary Effects on Health
- Cannabis and Cannabinoid Research
- Obesity, Physical Activity, Diet
- HIV Research and Treatment
- Nutritional Studies and Diet
- Pain Management and Opioid Use
- Pancreatitis Pathology and Treatment
- Folate and B Vitamins Research
- Palliative Care and End-of-Life Issues
- Iron Metabolism and Disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Gut microbiota and health
- Teacher Professional Development and Motivation
- Family Caregiving in Mental Illness
University of Florida
2023-2025
Florida International University
2016-2024
Institute on Aging
2023-2024
Iron plays a crucial role in many physiological processes, including oxygen transport, bioenergetics, and immune function. is assimilated from food also recycled senescent red blood cells. exists two dietary forms: heme (animal based) non-heme (mostly plant based). The body uses iron for metabolic purposes, stores the excess mainly splenic hepatic macrophages. Physiologically, excretion humans inefficient not highly regulated, so regulation of intestinal absorption maintains homeostasis....
Time-restricted eating (TRE) has been associated with beneficial effects for inflammation and oxidative stress; however, the of TRE on stress in aging population have not explored. This secondary analysis tested pro-inflammatory (hs-CRP [high-sensitivity C-reactive protein], IL-1β [interleukin 1 beta], IL-6 6], TNF-α [tumor necrosis factor alpha]) (8-isoprostane) biomarkers ten overweight older adults (mean age = 77.1 ± 6.1 years; six women four men), who followed a protocol 16 h fasting per...
<title>Abstract</title> Chronic pain is the most common health challenge for older adults and a significant risk factor cognitive impairments dementia. This study examined relationship between high-impact (pain that limits daily activities) subjective decline (SCD) in 13,763 aged 50 from Health Retirement Study (2004–2020). High-impact was associated with higher prevalence incidence of SCD as compared to no low-impact pain, adjusted sociodemographic clinical factors. Additionally, predicted...
Socioeconomic disadvantages and potential immunocompromise raise particular concerns for people living with HIV (PLWH) other marginalized communities during the COVID-19 pandemic. In this study, we explored testing impact of pandemic among participants from Miami Adult Studies on cohort, predominantly composed low-income minorities without HIV.Between July August 2020, a telephone survey was administered to 299 assess testing, prevention behaviors, psychosocial stressors. Health care...
Abstract Objective: This study evaluated whether food insecurity (US Adult Food Security Survey) was associated with chronic pain (≥ 3 months) and high-impact (i.e. that limits work life) among US adults. Design: Cross-sectional analysis. Setting: Nationally representative sample of non-institutionalised adults in the USA. Participants: 79 686 from National Health Interview Survey (2019–2021). Results: Marginal, low very security were increased prevalence odds (OR: 1·58 (95 % CI 1·44, 1·72),...
Background: HIV infection disproportionally affects African Americans. Liver disease is a major cause of non-HIV morbidity and mortality in this population. Substance abuse accelerates may facilitate progression liver disease. This study investigated the relationship between sex differences cocaine use with injury, characterized as hepatic fibrosis. Materials Methods: A cross-sectional was conducted on 544 Americans [369 people living (PLWH) 175 seronegative] from Miami Adult Studies (MASH)...
Background: Cognitive impairment is common in people living with HIV (PLWH). Opioid drugs exert direct and indirect effects on cognitive processes, which may contribute to dysfunction among PLWH. This study was designed determine if opioid use associated whether the effect differs between PLWH HIV-uninfected adults. Other neuropsychiatric symptoms, such as depression apathy, were also examined. We conducted a cross-sectional analysis of 265 284 participants from Miami Adult Studies (MASH)...
Evidence for a relationship between polysubstance use, depression, and adherence to antiretroviral therapy (ART) is limited. The objectives of this study were examine the associations illicit drug, alcohol use with ART. People living HIV (PLHIV) from Miami Adult Studies on cohort asked about number doses their ART medication missed assess adherence. Harmful drinking was evaluated using Alcohol Use Disorders Identification Test substance assessed self-report urine screen. Center Epidemiologic...
Abstract Background Liver disease remains a significant cause of morbidity and mortality in HIV-infected persons. Soluble CD163 is marker Kupffer cell activation that highly associated with development hepatic fibrosis. The relative contributions HIV-associated systemic immune vs other etiologies injury are poorly characterized. Methods We utilized subjects the Miami Adult Studies on HIV (MASH) cohort to evaluate 464 participants including 361 people (PWH) 103 hepatitis C virus...
The Coronavirus Disease 2019 (COVID-19) pandemic has disproportionately impacted people who use drugs (PWUD). This study explored relationships between drug use, COVID-19 testing, vaccination, and infection. cross-sectional was conducted in Miami, Florida March 2021 October 2022 as part of the National Institutes Health (NIH) Rapid Acceleration Diagnostics-Underserved Populations (RADx-UP) initiative Miami Adult Studies on HIV (MASH) cohort. Users cannabis, cocaine/crack, heroin/fentanyl,...
Chronic pain has been associated with accelerated biological aging, which may be related to epigenetic alterations. We evaluated the association of high-impact (ie, that limits activities and function) a measure in nationally representative sample middle-aged older adults United States. Cross-sectional analysis 50 years age from 2016 Health Retirement Study. Epigenetic aging was derived 13 clocks based on DNA methylation patterns predict correlates morbidity mortality. Ordinary least squares...
Objective: This study aimed to determine the impact of personal health, body mass index (BMI), nutrition knowledge and self-efficacy on classroom food-related beliefs practices. Design: A cross-sectional design evaluated BMI, health (PHI), knowledge, practices pre-service teachers. Setting: Pre-service teachers were recruited from upper division elementary education courses at a university in southeast region USA. Participants ( n = 94) Hispanic (65%), White (60%) female (93%). Method:...
The gut–liver axis has been recognized as a potential pathway in which dietary factors may contribute to liver disease people living with HIV (PLWH). objective of this study was explore associations between quality, the fecal microbiome, metabolome, and health PLWH from Miami Adult Studies on (MASH) cohort. We performed cross-sectional analysis 50 MASH cohort utilized USDA Healthy Eating Index (HEI)–2015 measure diet quality. A Fibrosis-4 (FIB-4) score < 1.45 used strong indication that...
Abstract Persistent immune activation is a hallmark of human immunodeficiency virus (HIV) infection and thought to play role on chronic diseases in people with HIV (PWH). Food insecurity disproportionately prevalent PWH associated adverse health outcomes. We determined whether food was increased plasma levels soluble CD14, CD27, CD163 323 antiretroviral-treated from the Miami Adult Studies cohort. Nearly half (42.7%) participants were insecure, 85.5% virally suppressed (&lt;200...
Determine if cocaine use impacts gut permeability, promotes microbial translocation and immune activation in people living with HIV (PLWH) using effective antiretroviral therapy (ART).