A5050754069- interferon and immune responses
- Oral and Maxillofacial Pathology
- Oral and Craniofacial Lesions
- Nanoplatforms for cancer theranostics
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Photodynamic Therapy Research Studies
- HER2/EGFR in Cancer Research
- Oral and gingival health research
- Autophagy in Disease and Therapy
- Supramolecular Self-Assembly in Materials
- Oral Health Pathology and Treatment
- Cancer Immunotherapy and Biomarkers
- Immune Cell Function and Interaction
- Immune cells in cancer
- Cancer Treatment and Pharmacology
- Breast Cancer Treatment Studies
- RNA Interference and Gene Delivery
- Cancer-related molecular mechanisms research
- Fatigue and fracture mechanics
- Vascular Malformations and Hemangiomas
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2025
Sichuan University
2023-2025
National Clinical Research Center for Digestive Diseases
2023
Chemoresistance poses a significant challenge in the treatment of advanced head and neck squamous cell cancer (HNSCC). The role mechanism circular RNAs (circRNAs) HNSCC chemoresistance remain understudied. We conducted circRNA microarray analysis to identify differentially expressed circRNAs HNSCC. expression from tyrosylprotein sulfotransferase 2 (TPST2) gene miRNAs was evaluated through qPCR, while structure circTPST2 verified using Sanger sequencing RNase R. Through Western blotting,...
Abstract Background: Head and neck squamous cell cancer (HNSCC) is the most prevalent head malignancy. Chemoresistance a major challenge in treatment of advanced HNSCC. Circular RNAs (circRNAs) are essential for development chemoresistance. The role mechanism circRNAs regulation HNSCC chemoresistance much less explored. Methods: CircRNA microarray analysis was used to detect differentially expressed expression circTPST2 miRNAs cells assessed by qPCR, ring structure examined using Sanger...