Alfredo Santalla

ORCID: 0000-0001-9418-0564
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About
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Research Areas
  • Sports Performance and Training
  • Glycogen Storage Diseases and Myoclonus
  • Cardiovascular and exercise physiology
  • Muscle metabolism and nutrition
  • Sports injuries and prevention
  • Neurological disorders and treatments
  • Congenital Heart Disease Studies
  • Genetics and Neurodevelopmental Disorders
  • Genetic Neurodegenerative Diseases
  • Cardiovascular Effects of Exercise
  • Pulmonary Hypertension Research and Treatments
  • Diet and metabolism studies
  • Muscle Physiology and Disorders
  • Lysosomal Storage Disorders Research
  • Sport Psychology and Performance
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Child Nutrition and Feeding Issues
  • Growth Hormone and Insulin-like Growth Factors
  • Muscle activation and electromyography studies
  • Restless Legs Syndrome Research
  • Tracheal and airway disorders
  • Genetics and Physical Performance
  • Cerebral Palsy and Movement Disorders
  • Children's Physical and Motor Development
  • Heart Rate Variability and Autonomic Control

Universidad Pablo de Olavide
2015-2024

Universidad Europea de Canarias
2021-2024

Research Institute Hospital 12 de Octubre
2014-2023

Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable
2017-2020

Universitat Autònoma de Barcelona
2015

Brunel University of London
2015

Centre for Biomedical Network Research on Rare Diseases
2015

Universidad Europea
2001-2015

Universidad de Zaragoza
2014

Hospital Universitario Virgen de las Nieves
1992-2010

To compare the total exercise loads (intensity x volume) of Vuelta a España and Tour de France during last year.Seven professional road cyclists (28 +/- 1 yr; [OV0312]O(2max): 74.6 2.2 mL.kg-1.min-1) who participated in both years 1997, 1999, 2000, or 2001 were collected as subjects. They wore heart rate (HR) telemeter each stage two races, intensity was divided into three phases according to reference HR values obtained previous ramp cycle-ergometer test: phase I (<ventilatory threshold...

10.1249/01.mss.0000064999.82036.b4 article EN Medicine & Science in Sports & Exercise 2003-05-01

<h3>Background</h3> Published genotype/phenotype data on McArdle disease are limited in sample size. A single national (Spanish) registry of patients with was created the purpose analysing their genotypic and phenotypic characteristics. <h3>Methods</h3> cross sectional study conducted, collecting demographic, family history, clinical, genotype functional capacity from all diagnosed Spanish National Health System up to December 2010. <h3>Results</h3> 239 cases were recorded (all Caucasian...

10.1136/jnnp-2011-301593 article EN Journal of Neurology Neurosurgery & Psychiatry 2012-01-16

The study aimed to compare the chronic eccentric-overload training effects of unilateral (lateral lunge) vs bilateral (half-squat) using an inertial device, on hypertrophy and physical performance. Twenty-seven young team sports male players performed a 4 sets 7 repetitions eccentric overload training, biweekly for 6 weeks, distributed in lunge group (UG: age: 22.8 ± 2.9 years; body mass: 75.3 8.8 kg; height: 177.3 3.7 cm) squat (BG: 22.6 2.7 79.5 12.8 164.2 cm). Lower limb muscle volume,...

10.1371/journal.pone.0193841 article EN cc-by PLoS ONE 2018-03-28

To determine the relationship that exists between VO2max and cycling economy/efficiency during intense, submaximal exercise in world-class road professional cyclists. METHODS Each of 11 male cyclists (26+/-1 yr (mean +/- SEM); VO2max: 72.0 1.8 mL x kg(-1) min(-1)) performed: 1) a ramp test for O2max determination 2) constant-load 20-min duration at power output eliciting 80% subjects' previous 385 7 W). Cycling economy (CE) gross mechanical efficiency (GE) were calculated tests.CE GE...

10.1249/01.mss.0000039306.92778.df article EN PubMed 2002-12-01

Requena, B, García, I, Suárez-Arrones, L, Sáez de Villarreal, E, Naranjo Orellana, J, and Santalla, A. Off-season effects on functional performance, body composition, blood parameters in top-level professional soccer players. J Strength Cond Res 31(4): 939-946, 2017-To examine the of a standard off-season period (OSP) aerobic, sprint, jumping performances, composition team. Nineteen players were measured. The OSP included to 2 weeks no training (resting phase) 4-week moderate-training load...

10.1519/jsc.0000000000001568 article EN The Journal of Strength and Conditioning Research 2016-07-20

To describe the internal training load (ITL) of common sessions performed during a typical week and to determine relationships between different indicators ITL commonly employed in professional football (soccer).Session-rating-of-perceived-exertion TL (sRPE-TL) heart-rate- (HR) derived measurements as Edwards Stagno impulses (TRIMPMOD) were used 9 players 3 periods season. The them analyzed week: skill drills/circuit + small-sided games (SCT+SSGs), ball-possession games+technical-tactical...

10.1123/ijspp.2014-0294 article EN International Journal of Sports Physiology and Performance 2014-12-04

Purpose: To compare endurance, strength and body composition indicators between cyclists of three different competition age categories. Methods: Fifty-one male road classified as either junior ( n = 13, 16.4 ± 0.5 years), under-23 [(U23), 24, 19.2 1.3 years] or professional 14, 26.1 4.8 years) were studied. Endurance (assessed through a maximal incremental test an 8-minute time-trial), strength/power loading tests for the squat, lunge hip thrust exercises) dual energy X-ray absorptiometry)...

10.3389/fphys.2022.945552 article EN cc-by Frontiers in Physiology 2022-08-05

To determine the effects of changes in pedaling frequency on gross efficiency (GE) and other physiological variables (oxygen uptake (VO2), HR, lactate, pH, ventilation, motor unit recruitment estimated by EMG) professional cyclists while generating high power outputs (PO).Following a counterbalanced, cross-over design, eight (age (mean +/- SD): 26 2 yr, VO2max: 74.0 5.7 mL x kg min) performed three 6-min bouts at fixed PO 366 37 W) cadence 60, 80, 100 rpm.Values GE averaged 22.4 1.7, 23.6...

10.1249/01.mss.0000128249.10305.8a article EN Medicine & Science in Sports & Exercise 2004-06-01

LUCÍA, A., J. HOYOS, M. PÉREZ, A. SANTALLA, and L. CHICHARRO. Inverse relationship between V̇O2max economy/efficiency in world-class cyclists. Med. Sci. Sports Exerc., Vol. 34, No. 12, pp. 2079–2084, 2002. Purpose To determine the that exists cycling during intense, submaximal exercise road professional Methods Each of 11 male cyclists (26 ± 1 yr (mean SEM); V̇O2max: 72.0 1.8 mL·kg−1·min−1) performed: 1) a ramp test for determination 2) constant-load 20-min duration at power output eliciting...

10.1097/00005768-200212000-00032 article EN Medicine & Science in Sports & Exercise 2002-12-01

We recently described the genotype/phenotype features of all Spanish patients diagnosed with McArdle disease as January 2011 (n = 239, prevalence ~1/167,000) (J Neurol Neurosurg Psychiatry 2012;83:322-8). Several caveats were however identified suggesting that is actually higher.We have now updated main data, well potential associations within/between them, individuals currently (December 2016).Ninety-four new (all Caucasian) been diagnosed, yielding a ~1/139,543 individuals. Around 55%...

10.1186/s12864-017-4188-2 article EN cc-by BMC Genomics 2017-11-01

The aim of the study was to investigate relationships between countermovement jump (CMJ) height and inertial power in squat sprint variables with change direction (COD) performance. Fifty young healthy active males participated study. To determine these relationships, we carried out a 10-m linear test (T 10 m), vertical tests (CMJ CMJ Abalakov), an assessment relative bodyweight flywheel (Pbw), COD sprints two different turn types (COD-90° COD-180°). T10 m showed statistically large moderate...

10.3390/sports8030038 article EN cc-by Sports 2020-03-19

By an initiative of the International Association Muscle Glycogen Storage Disease (IamGSD), international workshop was organised in form several digital meetings to provide a document as resource for clinicians regarding current best practice related diagnosis and management Diseases (GSDs) V (McArdle) VII (Tarui).

10.1016/j.nmd.2021.10.006 article EN cc-by-nc-nd Neuromuscular Disorders 2021-10-29

To investigate the relationship between several physiological variables that can be easily obtained during cycle ergometer gradual testing (for example, peak power output (W(peak)), Vo(2max), or ventilatory threshold (VT)) and actual (>50 km) time trials (TT) performance Tour de France.We collected data in professional cyclists from first TT of 1998 France (TT1, 58 km distance; n = 6 cyclists) (TT2, 56.5 km; 5) second 1999 (TT3, 57 5).A negative was found (W) at VT (VT(Watt)) final (s) TT1...

10.1136/bjsm.2003.008490 article EN British Journal of Sports Medicine 2004-09-23

We analyzed the effects of a 4-month resistance (weight lifting) training program followed by 2-month detraining period in 7 adult McArdle patients (5 female) on: muscle mass (assessed DXA), strength, serum creatine kinase (CK) activity and clinical severity. Adherence to was ≥84% all no major contraindication or side effect noted during strength assessment sessions. The had significant impact on total lower extremities' lean (P < 0.05 for time effect), with mean values increasing +855 g...

10.3389/fnagi.2014.00334 article EN cc-by Frontiers in Aging Neuroscience 2014-12-11

The speed performance is involved not only in linear sprints, but also a wide spectrum of multi-directional movements, such as curve sprinting. Curved sprint can be defined with gradual and continuous change direction (COD). Although ~85% the actions performed at maximum velocity professional soccer league are curvilinear there any specific test to assess this ability. This study aimed analyse reliability new test, compare its results those obtained by players sprint. Forty experienced 3...

10.1080/02640414.2019.1677391 article EN Journal of Sports Sciences 2019-10-13

Abstract Background The European registry for patients with McArdle disease and other muscle glycogenoses (EUROMAC) was launched to register rare in Europe, facilitate recruitment research trials learn about the phenotypes disseminate knowledge diseases through workshops websites. A network of twenty full collaborating partners from eight countries US contributed data on glycogenosis EUROMAC registry. After approximately 3 years collection, analysed. Results Of 282 confirmed diagnoses...

10.1186/s13023-020-01562-x article EN cc-by Orphanet Journal of Rare Diseases 2020-11-24

LUCÍA, A., J. HOYOS, A. SANTALLA, M. PÉREZ, and L. CHICHARRO. Kinetics of V̇O2 in professional cyclists. Med. Sci. Sports Exerc., Vol. 34, No. 2, pp. 320–325, 2002. Purpose To analyze the kinetics oxygen uptake (V̇O2) road cyclists during a ramp cycle ergometer test to compare results with those derived from well-trained amateur Methods Twelve (P group; 25 ± 1 yr; maximal power output (Wmax), 508.3 9.3 watts) 10 (A 22 y; Wmax, 429.9 8.6 performed until exhaustion (power increases...

10.1097/00005768-200202000-00021 article EN Medicine & Science in Sports & Exercise 2002-02-01

To determine the change in muscular efficiency world-class professional cyclists during years of training/competition.Twelve male road (mean +/- SD: age = 22.6 3.8 yr and VO(2max) 75.5 3.3 mL x kg(-1) min(-1)) performed an incremental test (starting at 100 W with workload increases 50 every 4-min interval until volitional exhaustion) before after a five-season period. Delta (DE) was calculated from to that power output (PO) which RER 1.DE increased (P < 0.01) 23.61 2.78% 26.97 3.7% first...

10.1249/mss.0b013e318191c802 article EN Medicine & Science in Sports & Exercise 2009-05-01

This study sought to determine whether health-related quality of life (HRQoL) could be related cardiorespiratory fitness (CRF) and/or physical activity (PA) in patients with McArdle disease and compare the CRF HRQoL data obtained normative for age- sex-matched healthy subjects.Eighty-one adult underwent aerobic capacity testing peak oxygen uptake (V˙O2peak), among other variables. (Short Form 36-Item Health Survey questionnaire version 2 (SF-36 2)) PA (International Physical Activity...

10.1249/mss.0000000000000458 article EN Medicine & Science in Sports & Exercise 2014-07-24

This study investigated the time-motion characteristics of football teams in Spanish first division, relation to their final competitive level as defined by league position (Champions League, Europa Upper mid-table, lower mid-table and relegation). Match observations (n = 9641) were collected using a multiple-camera computerized tracking system during 2013-2014 season. The following match parameters analyzed: total distance, relative distance (m·min-1), < 14 km·h-1, >14 between 14-21 >21 >24...

10.3390/sports7100216 article EN cc-by Sports 2019-09-30
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