A5057794087- Orthopedic Infections and Treatments
- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Spinal Fractures and Fixation Techniques
- Scoliosis diagnosis and treatment
- Spine and Intervertebral Disc Pathology
- Hip disorders and treatments
- Bone Tissue Engineering Materials
- Additive Manufacturing and 3D Printing Technologies
- Hydrogels: synthesis, properties, applications
- Cervical and Thoracic Myelopathy
- Bone fractures and treatments
- Bone and Joint Diseases
- Blood transfusion and management
- Hematological disorders and diagnostics
- Medical Imaging and Analysis
- Infectious Diseases and Tuberculosis
- Aerogels and thermal insulation
- Graphene and Nanomaterials Applications
- Nanoplatforms for cancer theranostics
- Pelvic and Acetabular Injuries
- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- Pleural and Pulmonary Diseases
- Peripheral Neuropathies and Disorders
Sichuan University
2015-2025
West China Hospital of Sichuan University
2015-2025
Inform (Germany)
2017
University of Washington
1974
Hydroxyapatite (HA), the traditional bone tissue replacement material was widely used in clinical treatment of defects because its excellent biocompatibility. However, processing difficulty and poor osteoinductive ability greatly limit application HA. Although many strategies have been reported to improve machinability osteointegration ability, performance including mechanical strength, porosity, cell adhesion, etc. still can not meet requirements. In this work, a soft template method...
We aimed to compare the effect of tourniquet use or lack it on recovery following uncomplicated primary total knee arthroplasty (TKA). In a prospective randomised double-blinded study, 150 patients undergoing TKA were assigned either non-tourniquet group. At early phase, 3 and 6 months after surgery, an independent observer assessed outcome measure (i.e. blood loss) secondary measures wound complications, visual analogue scale pain score range motion). The group exhibited reduced...
Immunomodulatory biomaterials have emerged as promising treatment agents for bone defects. However, it is unclear how such control immune cell behaviors to facilitate large-segment defect repair. Herein, we fabricated biphasic calcium phosphate ceramics with nanowhisker structures explore the immunoregulation features and influence on We found that markedly facilitated repair by promoting regeneration scaffold resorption. Our in vitro experiment transcriptomic analysis showed mechanical...
Hydrogel, recognized as a promising biomaterial for tissue engineering, possesses notable characteristics, including high water uptake, an interconnected porous structure, and excellent permeability. However, the intricate task of fabricating hierarchically macro–micronanoporous essential providing adequate space nutrient diffusion cell growth within hydrogels, remains formidable challenge. In response to these challenges, this study introduces sustainable straightforward three-dimensional...
Recently, digital light processing (DLP) 3D printing has garnered significant interest for fabricating high-fidelity hydrogels. However, the intrinsic weak and loose network of hydrogels, coupled with uncontrollable projection, leads to low resolution restricts their broader applications. Herein, we propose a straightforward DLP strategy utilizing in situ phase separation produce high-fidelity, high-modulus, biocompatible By selecting acrylamide monomers poor compatibility within polyvinyl...
Several studies have explored cervical kyphosis (CK) in adolescent idiopathic scoliosis (AIS) patients. However, few evaluated the alignment these patients according to their coronal curve type. The aim of this study was analyze radiological features sagittal Lenke 1 AIS before and after surgery. This is a retrospective enrolled 50 Preoperative postoperative standing full-length radiographs (at last follow-up operation) were used measure parameters. Main parameters included C2–C7 angle,...
We investigated the advantages of robotic arm-assisted total knee arthroplasty (raTKA) over conventional manual TKA (cmTKA) by comprehensively comparing patients who received raTKA and cmTKA in terms postoperative pain, function, imaging assessment, trauma to body. This study efficacy safety using YUANHUA-TKA system.
Abstract Background Revision total hip arthroplasty (THA) with severe femoral bone defects remains a major challenge. The purpose of this study is to report the minimum 8-year clinical and radiographic results revision THA treated extensively porous-coated stems cortical strut allografts. Methods We retrospectively identified 44 patients diagnosed Paprosky type III IV between January 2006 July 2011. exclusion criteria were not eligible for surgery, revised alone, lost follow-up deceased. A...
The HPHG features a multi-level porous structure (from 48 ± 28 nm to 4385 823 nm) that significantly enhances its porosity and specific surface area.
Abstract Background Severe acetabular bone defects is a complex problem in revision hip arthroplasty, cage one of the reconstruction options. The purpose this study to report mid-long term clinical and radiographic results Paprosky type III revised with reconstructional morselized allogeneic cancellous graft without impaction. Methods We retrospectively analyzed 28 patients who underwent arthroplasty between January 2007 2016. There were 13 IIIA defect 15 IIIB 4 also pelvic discontinuity....
Abstract Background Stress shielding and bone loss of the femur are great concern after revision total hip arthroplasty (THA) with extensively porous-coated stems, especially in a already loss. The femoral remodeling patterns THA defects using stems cortical strut allografts remain unclear. Methods We retrospectively reviewed 47 patients who underwent combined 75 without allografts. minimum follow-up was 2 years. Femoral signs, including stress shielding, restoration defect area, distal...
Abstract Background Overt hypothyroidism is widely accepted as a risk factor for adverse events following total knee arthroplasty (TKA). However, no prior study has preoperatively reversed and reevaluated its risk. This retrospective aimed at investigating whether well‐controlled overt would still increase the of TKA. Methods Between November 2009 2016, patients diagnosed with but well controlled underwent TKA were compared euthyroid patients. Data extracted from our departmental database....