A5103248687- Advanced biosensing and bioanalysis techniques
- Identification and Quantification in Food
- RNA Interference and Gene Delivery
- Fish Biology and Ecology Studies
- Ichthyology and Marine Biology
- Marine and fisheries research
- Parasite Biology and Host Interactions
- Crustacean biology and ecology
- Genomics and Phylogenetic Studies
- Fish Ecology and Management Studies
- Mercury impact and mitigation studies
- Marine Bivalve and Aquaculture Studies
- Heavy metals in environment
- Marine Biology and Ecology Research
- Genetic diversity and population structure
- Reproductive biology and impacts on aquatic species
- Aquaculture Nutrition and Growth
- Coral and Marine Ecosystems Studies
- Marine Ecology and Invasive Species
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Bacteriophages and microbial interactions
- Nanoplatforms for cancer theranostics
- Biosensors and Analytical Detection
- Environmental DNA in Biodiversity Studies
- Geochemistry and Geologic Mapping
National Center for Nanoscience and Technology
2022-2025
Zhengzhou University
2022-2025
Henan Institute of Technology
2025
Center for NanoScience
2025
Ministry of Agriculture and Rural Affairs
2019-2024
Chinese Academy of Fishery Sciences
2016-2024
University of Science and Technology of China
2021-2024
Hefei Institutes of Physical Science
2021-2024
Chinese Academy of Sciences
2016-2024
Anhui Institute of Optics and Fine Mechanics
2021-2024
DNA origami has played an important role in various biomedical applications, including biosensing, bioimaging, and drug delivery. However, the function of long scaffold involved yet to be fully exploited. Herein, we report a general strategy for construction genetically encoded by employing two complementary strands functional gene as therapy. In our design, sense antisense can directly folded into monomers their corresponding staple strands. After hybridization, assembled with precisely...
Developing a coreactant-free ratiometric electrochemiluminescence (ECL) strategy based on single luminophore to achieve more accurate and sensitive microRNA (miRNA) detection is highly desired. Herein, utilizing zinc-metal organic frameworks (Zn-MOFs) as the luminophore, novel dual-potential ECL biosensor was constructed for ultrasensitive of miRNA-133a. The as-prepared Zn-MOFs exhibited simultaneous cathode anode emission. Furthermore, were confirmed be multichannel sensing platform with...
As a class of electrochemiluminescence (ECL) enhancers, silver-based materials have broad application prospects. In this work, novel silver metal–organic framework (AgMOF) was developed as self-enhanced ECL emitter by one-step mixing and standing at room temperature. The AgMOF could produce strong stable emissions based on double-amplification method, which originated from the aggregation-induced emission ligands catalyzing S2O82– to more SO4•– silver. Moreover, an resonance energy transfer...
Abstract DNA nanostructures have played an important role in the development of novel drug delivery systems. Herein, we report a origami‐based CRISPR/Cas9 gene editing system for efficient therapy vivo. In our design, PAM‐rich region precisely organized on surface origami can easily recruit and load sgRNA/Cas9 complex by PAM‐guided assembly pre‐designed DNA/RNA hybridization. After loading complex, be further rolled up locking strands with disulfide bond. With incorporation aptamer influenza...
DNA origami, comprising a long folded scaffold and hundreds of linear staple strands, has been developed to construct various sophisticated structures, smart devices, drug delivery systems. However, the size diversity origami are usually constrained by length scaffolds themselves. Herein, we report new paradigm scaling up assembly introducing novel branched concept. Owing their covalent characteristics, chemically conjugated staples describe here can be directly added typical system obtain...
The nearshore ecosystem of Hainan Island plays a crucial role as breeding habitat for wide variety economically valuable fish species. Gaining insight into the structure community and environmental factors that may impact them is highly significant in this marine region. This study collected data from 50 sampling sites using bottom trawling surveys. Methods including swept area method, ecological indices, abundance/biomass curve (ABC) analysis were employed to assess resource density...
Heavy metal contamination is an elevating threat to the aquatic environment of estuarine bays. In present study, surface sediments from Shantou Bay in South China were collected and detected for concentrations heavy metals including copper (Cu), zinc (Zn), chromium (Cr), nickel (Ni), cadmium (Cd), lead (Pb) using ICP-MS. Spatial distribution, temporal trend, potential ecological risks pollution discussed. The results showed that levels generally decreased by order Zn > Pb Cr Cu Ni Cd....
Atmospheric aerosols play a pivotal role in the earth-atmospheric system. Analyzing their optical properties, specifically absorption and scattering coefficients, is essential for comprehending impact of on climate. When different properties are individually measured using multiple devices, cumulative errors detection results inevitably occur. To address this challenge, based photoacoustic spectroscopy (PAS) integrating sphere (IS) enhancement, compact gas cell (PASIS-Cell) was developed....
The concentration of trace gases in the atmospheric environment is extremely low, but it has a great impact on living organisms. Photoacoustic spectroscopy attracted extensive attention field gas detection because its high sensitivity, good selectivity, and fast response. As core photoacoustic setup, cell significant performance. To improve sphere-tube coupled (STPAC) was developed, which mainly composed diffuse-reflective sphere an acoustic resonance tube. Modulated light reflected multiple...
Development of effective conservation and management strategies requires assessments ecosystem biodiversity status, especially in understudied hotspots global fish diversity. Coral reefs are important habitats for fishes, with known globally. We present the first data on molecular diversity fishes Mischief Reef, largest atoll Nansha Islands. Partial sequences (650 bp) mitochondrial COI gene (Cytochrome c oxidase subunit I) used to identify 209 individuals, representing 101 species, referable...
Six heavy metals (As, Cu, Cd, Zn, Cr, and Pb) in surface sediments (0–5 cm) from the twenty selected sites of coastal Pearl Bay (South China Sea) were analyzed to assess distribution pattern potential ecological risk. Overall concentrations (mg/kg, dw) sediment samples were: As (10.88 ± 6.50), Cu (24.16 18.63), Cd (0.55 0.78), Zn (48.53 30.06), Cr (35.78 28.66), Pb (31.28 18.50). Results showed that overall mean values exceeded standard Marine Sediment Quality, caused by significantly high...
In recent years, microplastics have been widely detected in marine fish and may pose potential risks to human health. Even though microplastic pollution is a critical issue, it represents as yet non-quantified threat for some context the environment. this study, 271 individuals comprising 32 species of collected from Beibu Gulf were examined prevalence, with an aim provide data on abundance, physical classification, chemical characterization great bay along South China Sea. The results...
Portunus sanguinolentus (Herbst, 1783) is commercially important in China, but its yields have declined recent years. Here, the morphometric characteristics and organ indices are analysed to obtain baseline information about population structure, sexual maturity, fecundity of this species. Specimens were collected monthly from waters Honghai Bay, off South China Sea. A 1.26:1 male:female sex ratio was recorded. Male crabs reached maturity at a carapace width (CW) |$74{\rm{ -...