A5101568131- Advanced biosensing and bioanalysis techniques
- Advanced Nanomaterials in Catalysis
- Molecular Sensors and Ion Detection
- Electrochemical sensors and biosensors
- Electrochemical Analysis and Applications
- Metal-Organic Frameworks: Synthesis and Applications
- Nanocluster Synthesis and Applications
- Carbon and Quantum Dots Applications
- Luminescence and Fluorescent Materials
- RNA Interference and Gene Delivery
- Gold and Silver Nanoparticles Synthesis and Applications
- Biosensors and Analytical Detection
- Analytical Chemistry and Sensors
- Gastric Cancer Management and Outcomes
- X-ray Diffraction in Crystallography
- Antibiotics Pharmacokinetics and Efficacy
- Advanced Photocatalysis Techniques
- Advanced Chemical Sensor Technologies
- Metastasis and carcinoma case studies
- Protein Interaction Studies and Fluorescence Analysis
- Analytical chemistry methods development
- Crystallization and Solubility Studies
- Supramolecular Self-Assembly in Materials
- Ammonia Synthesis and Nitrogen Reduction
- Stock Market Forecasting Methods
Sun Yat-sen University
2012-2025
Sun Yat-sen University Cancer Center
2012-2025
State Key Laboratory of Oncology in South China
2015-2025
Chongqing Technology and Business University
2024-2025
Monash University
2025
Guangzhou Medical University Cancer Hospital
2024
Guangzhou Medical University
2024
Southwest University
2015-2024
Qingdao University
2019-2023
State Ethnic Affairs Commission
2023
Surface-enhanced Raman scattering (SERS) signals are intensively dominated by the hot spots and distance between analyte molecules metallic nanostructures. Herein, an efficient SERS substrate was developed in situ synthesis of silver nanoparticles (AgNPs) on surface MIL-101 (Fe), a typical metal–organic framework (MOF). The as-prepared combines numerous high-density Ag NPs excellent adsorption performance MOFs, making it for highly sensitive detection effectively concentrating analytes close...
A familiar metal–organic framework MIL-101(Fe) and silver nanoparticles composite acted as a novel electrode modified material for the detection of tryptophan.
Developing a coreactant-free ratiometric electrochemiluminescence (ECL) strategy based on single luminophore to achieve more accurate and sensitive microRNA (miRNA) detection is highly desired. Herein, utilizing zinc-metal organic frameworks (Zn-MOFs) as the luminophore, novel dual-potential ECL biosensor was constructed for ultrasensitive of miRNA-133a. The as-prepared Zn-MOFs exhibited simultaneous cathode anode emission. Furthermore, were confirmed be multichannel sensing platform with...
As a class of electrochemiluminescence (ECL) enhancers, silver-based materials have broad application prospects. In this work, novel silver metal–organic framework (AgMOF) was developed as self-enhanced ECL emitter by one-step mixing and standing at room temperature. The AgMOF could produce strong stable emissions based on double-amplification method, which originated from the aggregation-induced emission ligands catalyzing S2O82– to more SO4•– silver. Moreover, an resonance energy transfer...
The N6-methyladenosine (m6A) modification serves as an essential epigenetic regulator in eukaryotic cells, playing a significant role tumorigenesis and cancer progression. However, the detailed biological functions underlying mechanisms of m6A regulation gastric (GC) are poorly understood. Our research revealed that demethylase ALKBH5 was markedly downregulated GC tissues, which associated with poor patient prognosis. Functional studies demonstrated suppressing expression enhanced cell...
Peroxynitrite (ONOO–), a highly reactive nitrogen species (RNS) generated mainly in mitochondria, has been identified to be associated with numerous pathophysiological processes, and thus accurate ONOO– imaging superior sensitivity selectivity is desirable. Herein, we prepared new type of carbon quantum dots (CQDs) mitochondria-targeting function without the aid any targeting molecules via simple one-step hydrothermal route. The as-prepared CQDs not only displayed relatively uniform size...
In this work, a novel aluminum metal–organic framework (Al-MOF)/N-2-hydroxyethylpiperazine-N′-ethane-sulfonic acid (HEPES) system with an excellent electrochemiluminescence (ECL) property was developed. First, Al-MOF successfully synthesized through one-pot solvothermal method by using 9,10-di(p-carboxyphenyl)anthracene (DPA) as the organic luminescence ligand and Al3+ metal node. Compared DPA, showed high ECL intensity stability without additional coreactant in HEPES buffer. The...
This study developed a new zirconium metal–organic framework (MOF) luminophore named Zr-DPA@TCPP with dual-emission electrochemiluminescence (ECL) characteristics at resolved potential. First, core–shell structure was effectively synthesized through the self-assembly of 9,10-di(p-carboxyphenyl)anthracene (DPA) and 5,10,15,20-tetra(4-carboxyphenyl)porphyrin (TCPP) as respective organic ligands Zr cluster metal node. The reasonable integration two DPA TCPP ECL properties into single monomer,...
Enzyme-like catalytic activity and efficiency of carbon-based nanomaterials are closely linked to their size, heteroatom composition, structure, hence the regulation needs be further explored. In this work, a simple efficient strategy was proposed develop Cu-doped 2D carbon material C3N4 (Cu-C3N4-550) with excellent performance by pyrolyzing precursors Cu(II) metal–organic gel (MOG) melamine directly. Due its sufficient metal active sites adequate specific surface areas, as-prepared...