- Advanced biosensing and bioanalysis techniques
- Textile materials and evaluations
- Biosensors and Analytical Detection
- Toxin Mechanisms and Immunotoxins
- Transgenic Plants and Applications
- Carbon and Quantum Dots Applications
- Nanoplatforms for cancer theranostics
- Photoacoustic and Ultrasonic Imaging
- DNA and Nucleic Acid Chemistry
- Bioactive Compounds and Antitumor Agents
- Molecular Sensors and Ion Detection
- Nanoparticle-Based Drug Delivery
- Engineering Structural Analysis Methods
- Dynamics and Control of Mechanical Systems
- Structural Analysis and Optimization
- Advanced Memory and Neural Computing
- Surface Modification and Superhydrophobicity
- Crafts, Textile, and Design
- Dyeing and Modifying Textile Fibers
- Polymer Surface Interaction Studies
- Electrochemical sensors and biosensors
- Ultrasound and Hyperthermia Applications
- Ultrasound Imaging and Elastography
- Lanthanide and Transition Metal Complexes
- Extracellular vesicles in disease
Shanghai Civil Aviation College
2024
Southwest University
2021-2022
Chongqing Medical and Pharmaceutical College
2017-2021
Chongqing Medical University
2017-2021
Chongqing University
2019-2021
Pharmaceutical Biotechnology (Czechia)
2021
Zhejiang University of Technology
2019
Shanghai University of Engineering Science
2006-2013
Shenyang Aerospace University
2012
The University of Texas at Austin
2008-2010
Peroxynitrite (ONOO–), a highly reactive nitrogen species (RNS) generated mainly in mitochondria, has been identified to be associated with numerous pathophysiological processes, and thus accurate ONOO– imaging superior sensitivity selectivity is desirable. Herein, we prepared new type of carbon quantum dots (CQDs) mitochondria-targeting function without the aid any targeting molecules via simple one-step hydrothermal route. The as-prepared CQDs not only displayed relatively uniform size...
Hyaluronic acid and polydopamine functionalized phase change nanoparticles for ultrasound imaging-guided photothermal-chemotherapy.
A novel organic/inorganic hybrid nanovesicle as an ultrasound imaging agent is synthesized via facile emulsion and silica deposition methods. This nanovesicle, hyaluronate (HA)-docetaxel (DTX)/perfluoro-n-pentane (PFP)@SNC, consists of encapsulated liquid PFP core, loaded DTX, HA-decorated shell. The HA-DTX/PFP@SNC has a narrow size distribution 274.5 ± 3.25 nm, negative zeta potential -11.6 0.47 mV, entrapment efficiency 86.70% 1.42%. possesses (US)-triggered drug release...
A homo-FRET enhanced ratiometric fluorescence method has been developed successfully for the detection of Exo III activity.
Inspired by the specific optical properties of DNA photonic nanowires (PNs) on which fluorescent dyes are to be precisely positioned and energy transfer over nanometers can achieved, herein, we develop a PN-based homogeneous entropy-driven biomolecular assay (HEBA). Using Förster resonance (FRET) Cy3, constructed PN capable transferring from green donor dye (FAM) red acceptor fluorophore (Cy5) across total distance 10.2 nm with an end-to-end efficiency 13.2%. By taking PNs as substrate...
Oxazolo[5,4-d]pyrimidines can be considered as 9-oxa-purine analogs of naturally occurring nucleic acid bases. Interest in this ring system has increased due to recent reports biologically active derivatives. In particular, 5-aminooxazolo[5,4-d]pyrimidine-7(6H)-ones (9-oxa-guanines) have been shown inhibit ricin. The preparation a series 2-substituted 5-aminooxazolo[5,4-d]pyrimidin-7(6H)-ones and related 5-thio-oxazolo[5,4-d]pyrimidines is described, including suitable for further...
We reported a novel strategy that combined Cu-based metal–organic gel (Cu-MOG) with an entropy-driven circuit (EDC) to detect miR-155 as proof-of-principle target.
With the coordinated development of China’s national economy and people’s awareness importance physical mental health, people have become active in sports, sports medical care for athletes is particularly important. In training, are likely to ligament injuries, which makes face rehabilitation, prevention other problems. This paper describes joint structure, injury factors preventive measures anterior cruciate ligament, compares detection algorithm based on multimedia visual image with...
The chemical conjugation of antibodies to protein toxins results in cell-specific cytotoxic agents that can be defined terms vitro potency and efficacy; however, it is the vivo utilities are largely being pursued clinical trials. nature target cell depletion by toxin conjugates unknown. anti-murine Thy1.1 antibody-diphtheria conjugate possesses high efficacy, because mice remarkably resistant native toxin, efficacy. When administered intravenously, shown deplete peripheral blood Thy1.1+...
Many components in modern mechanical structure are connected with bolts, and the behaviour of joints significantly affects dynamic response these structures. Based on software MSC. patran, firstly, a linear model for bolted interface is developed. The joint modeled using technology layer element(ILE) multi-point constrains(MPC) technique. And then, MATLAB language, properties ILE material optimized to simulate bolted-joint stiffness. parameters identified by experimental data. This work...