Tatiane Santi‐Gadelha

ORCID: 0000-0001-9451-9820
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About
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Research Areas
  • Glycosylation and Glycoproteins Research
  • Protein Hydrolysis and Bioactive Peptides
  • Carbohydrate Chemistry and Synthesis
  • Meat and Animal Product Quality
  • Probiotics and Fermented Foods
  • Toxin Mechanisms and Immunotoxins
  • Proteins in Food Systems
  • Phytase and its Applications
  • Agricultural Practices and Plant Genetics
  • Microbial Metabolites in Food Biotechnology
  • Enzyme Production and Characterization
  • Biochemical Analysis and Sensing Techniques
  • Studies on Chitinases and Chitosanases
  • Growth and nutrition in plants
  • Transgenic Plants and Applications
  • Collagen: Extraction and Characterization
  • Galectins and Cancer Biology
  • Biochemical and Structural Characterization
  • Biopolymer Synthesis and Applications
  • Food Chemistry and Fat Analysis
  • Essential Oils and Antimicrobial Activity
  • Pharmacological Effects of Natural Compounds
  • Insect Resistance and Genetics
  • Pain Mechanisms and Treatments
  • Venomous Animal Envenomation and Studies

Universidade Federal da Paraíba
2016-2025

Universidade Federal do Ceará
2004-2006

The protein composition of goat milk differs between breeds and could present regional trends. aim this study was to comparatively analyze the produced by Alpine Saanen in northeastern Brazil evaluate antibacterial activity its fractions. SDS-PAGE, 2-DE electrophoresis RP-HPLC analyses revealed absence αs1-casein both no differences αs2-casein, β-casein, β-lactoglobulin α-lactalbumin profiles. amounts soluble proteins β-casein hydrolysis residues were higher milk. Only fraction containing...

10.1371/journal.pone.0093361 article EN cc-by PLoS ONE 2014-03-27

Lectins are mainly described as simple carbohydrate-binding proteins. Previous studies have tried to identify other binding sites, which possible recognize plant hormones, secondary metabolites, and isolated amino acid residues. We report the crystal structure of a lectin from Canavalia gladiata seeds (CGL), describing new pocket, may be related pathogen resistance activity in ConA-like lectins; site where non-protein amino-acid, α-aminobutyric (Abu), is bound. The overall native CGL...

10.1186/1472-6807-7-52 article EN cc-by BMC Structural Biology 2007-08-02

The objective of this study was to extract collagen from chicken feet, determining optimal extraction conditions according acetic acid concentration, pepsin content and time enzymatic hydrolysis. A factorial design 23 used, with three replications at the central point, totaling 11 experiments. response variable studied isolate obtained. In addition optimization, characterization isolates higher lower content, in relation amino profile, electrophoretic peptide hydrophobicity functional...

10.1590/fst.27517 article EN Food Science and Technology 2018-04-14

This study evaluated the impacts of Lactiplantibacillus plantarum CNPC003 and xique-xique flour supplementation on technological, physicochemical, nutritional, sensory properties goat cream cheese over 21 days refrigerated storage. Four formulations were prepared: a control (CC), one with L. (PC), (XC), (PXC). XC PXC had yellowish-green hue less brightness. PC firm adhesive greater elasticity, cohesiveness, gumminess, they reduced total protein increased free amino acids (p < 0.05) during...

10.3390/microorganisms13020254 article EN cc-by Microorganisms 2025-01-24

Lectins are proteins that have the ability to bind specifically and reversibly carbohydrates glycoconjugates, without altering structure of glycosyl ligand. They found in organisms such as viruses, plants humans, they been shown possess important biological activities. The objective this study was purify characterize lectins seeds Clitoria fairchildiana, well verify their results indicated presence a lectin (CFAL) glutelin acid protein fraction, which agglutinated native rabbit erythrocytes....

10.3390/molecules17033277 article EN cc-by Molecules 2012-03-14

The LYS49-PLA₂s myotoxins have attracted attention as models for the induction of myonecrosis by a catalytically independent mechanism action. Structural studies and biological activities demonstrated that myotoxic activity LYS49-PLA₂ is catalytic site. effect conventionally thought to be due C-terminal region 111-121, which plays an effective role in membrane damage. In present study, Bn IV was isolated from Bothrops neuwiedi snake venom complex with myristic acid (CH₃(CH₂)₁₂COOH) its...

10.1016/j.biochi.2010.11.003 article EN publisher-specific-oa Biochimie 2010-11-23

The lectin of Dioclea virgata (DvirL), both native and complexed with X-man, was submitted to X-ray diffraction analysis the crystal structure compared that other Diocleinae lectins in order better understand differences biological properties, especially regard ability induce nitric oxide (NO) production. An association observed between volume carbohydrate recognition domain (CRD), NO production relative positions Tyr12, Arg228 Leu99. Thus, activity induced by are related configuration amino...

10.1016/j.biochi.2011.12.009 article EN publisher-specific-oa Biochimie 2011-12-16

Indole-3-acetic acid (IAA) bound is considered a storage molecule and inactive. However, some studies have proposed an additional possible regulatory mechanism based on the ability of lectins to form complexes with IAA. We report first crystal structure ConM in complex IAA at 2.15 Å resolution. Based tetrameric model complex, we hypothesize how lectin controls availability during early seedling stages, indicating new physiological role for these proteins. A free indole group also protein....

10.1016/j.biochi.2013.05.008 article EN publisher-specific-oa Biochimie 2013-05-29
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