A5103131779- Wildlife Ecology and Conservation
- Animal Behavior and Welfare Studies
- Erythrocyte Function and Pathophysiology
- Rabies epidemiology and control
- Reproductive Physiology in Livestock
- Blood groups and transfusion
- Virology and Viral Diseases
- Human-Animal Interaction Studies
- Animal Ecology and Behavior Studies
- Animal Disease Management and Epidemiology
- Ecology and biodiversity studies
- Immune Response and Inflammation
- Iron Metabolism and Disorders
- High Altitude and Hypoxia
- Poxvirus research and outbreaks
- Herpesvirus Infections and Treatments
- Yersinia bacterium, plague, ectoparasites research
- Environmental Philosophy and Ethics
- Erythropoietin and Anemia Treatment
- Vector-Borne Animal Diseases
- Biochemical Acid Research Studies
- Zoonotic diseases and public health
- Bat Biology and Ecology Studies
- Veterinary Medicine and Surgery
- Pharmacological Effects and Toxicity Studies
University of York
2023-2024
Oxford Fertility
2024
University of Sassari
2023
Animal and Plant Health Agency
2013-2022
Fera Science (United Kingdom)
2010-2017
Institute of Industrial Ecology
1994
Summary In Nepal, most dogs are free to roam and may transmit diseases humans animals. These often suffer from malnutrition lack basic health care. Minimal information is available about their demographics public attitudes concerning diseases. We carried out a study in Chitwan District (central Nepal), collect baseline data on free‐roaming owned dog demographics, assess knowledge, practices of owners rabies, evaluate rabies vaccination coverage anthelmintic treatment dogs, measure dogs'...
Fertility control has the potential to be used as an attractive alternative lethal methods for limiting population growth in overabundant species. This study tested effectiveness and side effects of single-dose gonadotrophin-releasing hormone (GnRH) vaccine GonaCon on physiology behaviour two groups captive female wild boar sequential trials (Trial 1 Trial 2). Following vaccination with GonaCon, data contraceptive were recorded well time budget, social rank, bodyweight, haematology...
Accurate prediction of fluctuations wildlife local number individuals is crucial for effective population management to minimise human-wildlife conflicts. Climate, habitat, food availability, and density dependence are among the main factors influencing mammalian dynamics. In southern Europe, precipitation temperature, particularly during summer have been suggested as key affecting wild boar (Sus scrofa L.). However, there uncertainty regarding role these mechanisms driving fluctuations....
Controlling bovine tuberculosis (bTB) in livestock is often hindered by the presence of a wildlife reservoir, such as Eurasian badger UK and Ireland. Vaccinating badgers against bTB can reduce severity Mycobacterium bovis infection potential onwards transmission to cattle, other species, thus combined with population control might provide additional benefits (and reference models). To evaluate effects co-administration vaccine (BCG) contraceptive (GonaCon), captive were injected...
ContextRabies causes ~55 000 human deaths each year, primarily as a result of bites from dogs, which are the major rabies reservoir in developing world. Current control strategies include vaccination, culling and surgical sterilisation dogs. However, recently developed immunocontraceptives could be used alongside vaccination to apply fertility more animals. AimsWe modelling approach explore (1) whether adding single-dose contraceptives would improve effectiveness eradication, (2) how...
Context Fertility control appears as a publicly acceptable alternative to lethal methods for limiting population growth in wildlife. Recently developed single-dose immunocontraceptive vaccines have induced infertility several mammals. However, the potential side-effects and long-term effectiveness of these contraceptives been poorly investigated. Aims We tested gonadotrophin-releasing hormone (GnRH) vaccine GonaCon™ on captive female wild boar. Methods carried out two sequential trials:...
The economic and environmental impacts of wildlife are increasing in parallel with renewed public interest non-lethal methods, such as fertility control, to manage these impacts. Wildlife Research 2008 Special Issue on Fertility Control for (Vol. 35) published following the 6th International Conference held 2007 York, United Kingdom, reported studies effects contraceptives individual animals populations, most papers focusing ungulates. In past 15 years, significant progress has been made...
Conflicts between human interests and feral cattle in Hong Kong derive from growing numbers of free-roaming cattle. Public antipathy towards lethal population control led the local authorities to consider fertility reduce numbers. This study assessed potential side effects immunocontraceptive GonaCon on individual female established effectiveness induce infertility. We evaluated 34 captive assigned four groups: Control administered a sham solution; Webbed (surgically sterilized through...
1. As human-wildlife conflicts increase worldwide, novel methods are required for mitigating these conflicts. Fertility control, based on immunocontraceptives, has emerged as an alternative option to lethal managing wildlife.2. Immunocontraceptives vaccines that generate immune response key components of animal's reproductive system. Some target the gonadotropin-releasing hormone (GnRH) and have been used successfully contraceptives many wildlife species. However, need capture animals...
GonaCon, a single-shot injectable immunocontraceptive vaccine targeting the gonadotropin-releasing hormone (GnRH), has been tested in key mammal species UK and shown to be safe method reduce population size areas of high human wildlife conflict. Badgers exhibit an unusual reproductive physiology that females may maintain fertilised eggs dormant blastocysts at any time year delay their implantation until winter. It is thus necessary evaluate consequences delayed timing vaccination on...
Increasing human-wildlife conflicts worldwide are driving the need for multiple solutions to reducing “problem” wildlife and their impacts. Fertility control is advocated as a non-lethal tool manage free-living in particular iconic species. Injectable immunocontraceptives, such GonaCon, stimulate immune system produce antibodies against gonadotrophin-releasing hormone (GnRH), which turn affects release of reproductive hormones mammals. Feral cattle ( Bos indicus or taurus ) Hong Kong an...
The resolution of conflicts between human and wildlife interests often involves lethal control to reduce problem populations. However, has always had its limitations, the acceptable methods are becoming fewer, public opposition is on increase. Fertility offers a potential alternative approach that widely regarded as being inherently more benign. Furthermore, in some circumstances fertility may have specific advantages over culling. development "single-shot" injectable immunocontraceptive...
•Increases in human-wildlife conflicts alongside cultural shifts against lethal control methods are driving the need for alternative wildlife management tools such as fertility control. Contraceptive formulations suitable oral delivery would permit broader remote application species.•This study evaluated contraceptive effect and immune response to two novel injectable immunocontraceptive targeting Gonadotropin Releasing Hormone (GnRH): MAF-IMX294 MAF-IMX294P conjugates, both identified...
Abstract The grey squirrel ( Sciurus carolinensis ) is an invasive alien species in the United Kingdom (UK). economic impact of squirrels on England and Wales forestry estimated to be around £37 million ($47 USD) per year, presence this has caused decline native red vulgaris due interspecific competition transmission diseases. Oral contraceptives, delivered baits, are being developed control number UK. Bait uptake can affected by many factors that must understood develop effective delivery...