- Homelessness and Social Issues
- Substance Abuse Treatment and Outcomes
- Cannabis and Cannabinoid Research
- Musculoskeletal pain and rehabilitation
- Health Systems, Economic Evaluations, Quality of Life
- Child and Adolescent Psychosocial and Emotional Development
- Health disparities and outcomes
- Food Security and Health in Diverse Populations
- Racial and Ethnic Identity Research
- Psychological Well-being and Life Satisfaction
- Healthcare Policy and Management
- Smoking Behavior and Cessation
- Retinal Diseases and Treatments
- Emergency and Acute Care Studies
- Obesity and Health Practices
- Glaucoma and retinal disorders
- Behavioral Health and Interventions
- Obesity, Physical Activity, Diet
- Mental Health Research Topics
- Geriatric Care and Nursing Homes
- Patient Satisfaction in Healthcare
- Palliative Care and End-of-Life Issues
- Spine and Intervertebral Disc Pathology
- Community Health and Development
- Attachment and Relationship Dynamics
RAND Corporation
2017-2025
University of Southern California
2003-2023
University of California, Los Angeles
2015-2022
Southern California University for Professional Studies
2022
Massachusetts General Hospital
2018-2020
St. Luke's Medical Center
2020
Doheny Eye Institute
2003-2014
Central Bank of Venezuela
1977-1986
The purpose of this study was to apply a set rarely reported psychometric indices that, nevertheless, are important consider when evaluating psychological measures. All can be derived from standardized loading matrix in confirmatory bifactor model: omega reliability coefficients, factor determinacy, construct replicability, explained common variance, and percentage uncontaminated correlations. We calculated these extended the findings 50 recent model estimation studies published...
Abstract Pericyte loss and deficient vascular platelet-derived growth factor receptor-β (PDGFRβ) signaling are prominent features of the blood–brain barrier breakdown described in Alzheimer’s disease (AD) that can predict cognitive decline yet have never been studied retina. Recent reports using noninvasive retinal amyloid imaging, optical coherence tomography angiography, histological examinations support existence vascular-structural abnormalities β-protein (Aβ) deposits retinas AD...
Alzheimer's disease (AD) pathologies were discovered in the accessible neurosensory retina. However, their exact nature and topographical distribution, particularly early stages of functional impairment, how they relate to progression brain remain largely unknown. To better understand pathological features AD retina, we conducted an extensive histopathological biochemical investigation postmortem retina tissues from 86 human donors. Quantitative examination superior inferior temporal retinas...
Background Researchers have implemented multiple approaches to increase data quality from existing web-based panels such as Amazon’s Mechanical Turk (MTurk). Objective This study extends prior work by examining improvements in and effects on mean estimates of health status excluding respondents who endorse 1 or both 2 fake conditions (“Syndomitis” “Chekalism”). Methods Survey were collected 2021 at baseline 3 months later MTurk participants, aged 18 years older, with an internet protocol...
Abstract Purpose We describe development of a short health-related quality life measure, the patient-reported outcomes measurement information system® (PROMIS®)-16 Profile, which generates domain-specific scores for physical function, ability to participate in social roles and activities, anxiety, depression, sleep disturbance, pain interference, cognitive fatigue. Methods An empirical evaluation 50 candidate PROMIS items item pairs was conducted using data from sample 5775 respondents...
Bacterial meningitis occurs when bloodborne pathogens invade and penetrate the blood-brain barrier (BBB), provoking inflammation disease. Group B Streptococcus (GBS), leading cause of neonatal meningitis, can enter human brain microvascular endothelial cells (hBMECs), but host response to intracellular GBS has not been characterized. Here we sought determine whether antibacterial autophagy, which involves selective recognition organisms their targeting autophagosomes for degradation, is...
Abstract Aims We investigated associations between the density of medical marijuana dispensaries (MMDs) around young adults' homes and use outcomes. Design Secondary data analysis. Setting Los Angeles County, CA, USA. Participants A total 1887 participants aged 18–22 years, surveyed online in 2016–17. Measurements Outcomes were past‐month (number days used, number times each day), positive expectancies perceived peer use. Density was measured as MMDs with storefront signage indicative sales,...
To expand on epidemiologic studies examining associations between the legalization of recreational cannabis and use among young adults, we examined licensed unlicensed outlet density outcomes.A total 1097 adults aged 21 older living in Los Angeles County were surveyed before outlets opened (Time 1: July to December 2017) after 2: 2018 June 2019). Using a database open retailers calculate individual-level measures, within 4-mile radius participants' residences with Time 2 outcomes any...
This study examined longitudinal associations of sleep problems with alcohol and cannabis use across six annual waves data from adolescence to emerging adulthood.Participants were 3,265 youth California (ages 16-22 waves). At each wave, past-month use, mental health, several dimensions health (i.e. social jetlag, bedtimes, time in bed, trouble sleeping) assessed via questionnaire. Parallel process latent growth models the association between or trajectories role contributing such...
Young adults experiencing homelessness are at high risk for alcohol-related consequences, but protective behavioral strategies (PBS) have not been investigated as a harm reduction approach in this population. This study examines longitudinal associations between PBS and consequences following group-based alcohol intervention. Data come from AWARE, randomized controlled trial of motivational intervention to reduce substance use risky sex compared usual care. Participants include 276 young (...
Abstract Background Weight bias is a global health challenge and community members are endorsed as the most common source of weight bias. The nature biases specifically against preconception, pregnant, postpartum (PPP) women from perspective not known, especially in terms cross-cultural trends. We investigated magnitude explicit implicit profiles characteristics associated with harbouring Methods conducted multinational investigation clusters factors PPP (May–July 2023). Community Australia,...
Research suggests that up to a third of married individuals report low marital satisfaction, underscoring the importance studying unhappy marriages. Although numerous studies have investigated causes and consequences dissatisfaction, less is known about potential heterogeneity among within marriages extent which some unhappily spouses may be satisfied in other life domains. The present study sought determine whether categorical differences exist individuals. Using friendship family...