A5040098099- Ocular Surface and Contact Lens
- Reconstructive Facial Surgery Techniques
- Advanced Glycation End Products research
- Ocular Disorders and Treatments
- Acute Myocardial Infarction Research
- Science and Education Research
- Peptidase Inhibition and Analysis
- Atrial Fibrillation Management and Outcomes
- Health, Nursing, Elderly Care
- Sleep and Wakefulness Research
- HIV/AIDS Research and Interventions
- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Venous Thromboembolism Diagnosis and Management
- Antifungal resistance and susceptibility
- Facial Trauma and Fracture Management
- Omental and Epiploic Conditions
- Public Health in Brazil
- Reconstructive Surgery and Microvascular Techniques
- Obstructive Sleep Apnea Research
- Galectins and Cancer Biology
- Central Venous Catheters and Hemodialysis
- Pharmaceutical Economics and Policy
- Cleft Lip and Palate Research
- Skin Protection and Aging
Southwestern Medical Center
2022
The University of Texas Southwestern Medical Center
2021-2022
Universidade Federal de São Paulo
2020-2021
Universidade Estadual Paulista (Unesp)
2016
Universidade de São Paulo
1998
Risk factors for metabolic syndrome include abdominal obesity, insulin resistance, hypertension, high triglycerides and/or low high-density lipoprotein cholesterol, and hyperglycemia. have been associated with dry eye disease; however, their association meibomian gland disease (MGD), a subtype of eye, is unclear. In the present study, we investigated risk in cohort without MGD.This retrospective case-control study evaluated electronic medical records at major urban outpatient center to...
Mitochondrial dysfunction is a major pathophysiological event leading to the onset of diabetic complications. This study investigated temporal effects hyperglycemia on mitochondrial metabolism in corneal epithelial cells. To accomplish this, human telomerase-immortalized cells were cultured defined growth medium containing 6 mM glucose. simulate hyperglycemia, 25 D-glucose, and control mannitol. Using metabolic flux analysis, there was hyperosmolar-mediated increase respiration after 24 h....
Purpose: As an external mucosal surface, the corneal epithelium is subject to a barrage of stressors that are known trigger inflammation. IL-1b, master regulator inflammation, secreted into preocular tear film by ocular surface epithelial cells and infiltrating immune cells. While increased levels IL-1b have been associated with disease, effects on mitochondrial function in (CECs) unknown. Methods: To investigate function, telomerase immortalized human CECs were cultured either 50 ng/mL or...
Objective: To describe causes of orbital exenteration in a Brazilian tertiary hospital. Methods: A retrospective study was done, involving patients submitted to at the Clinical Hospital Botucatu Medical School, between years 1993 2016. The surgeries have been performed under general anesthesia, by multidisciplinary team, composed ophthalmologists, otolaryngologists and head neck surgeons. Results: Fourteen cases occurred period study, with mean age 63.36 ± [...]
Purpose Obstructive sleep apnea (OSA) is an established independent risk factor for peripheral neuropathy. Macro and microvascular changes have been documented in OSA, including high levels of potent vasoconstrictors. In diabetes, vasoconstriction has identified as underlying corneal This study sought to establish a potential relationship between OSA nerve morphology sensitivity, determine whether nerves may be reflective severity. Design Single center cross-sectional study. Methods...
Objective: The aim of this study was to evaluate the biocompatibility Nanoskin for replacing volume in enucleated or eviscerated anophthalmic sockets rabbits. Methods: An experimental carried out using rabbits, which received implants (Innovatecs®, São Carlos, Brazil), a cellulose produced by bacteria (Acetobacter xylinum) green tea as substrate. Implants 10mm diameter/5mm thickness were used placed (G1) (G2) 21 rabbits.They clinically examined [...]