About
Contact & Profiles
A5076461934
Research Areas
- Bladder and Urothelial Cancer Treatments
- Wnt/β-catenin signaling in development and cancer
- Cancer Cells and Metastasis
Children's Hospital of Philadelphia
2025
Massachusetts Institute of Technology
2018
10.1182/blood.2024027270
article
EN
cc-by-nc-nd
Blood
2025-03-16
10.1182/blood.2025028566
article
EN
Blood
2025-03-18
While many adhesion receptors are known to influence tumor progression, the mechanisms by which they dynamically regulate cell-cell remain elusive. We previously identified Activated Leukocyte Cell Adhesion Molecule (ALCAM) as a clinically relevant driver of metastasis and hypothesized that tunable mechanism ectodomain shedding regulates its contribution dissemination. To test this hypothesis, we examined an under-explored ALCAM splice variant (ALCAM-Iso2) demonstrated loss membrane-proximal...
10.1038/s41598-018-21467-x
article
EN
cc-by
Scientific Reports
2018-02-12
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