In recent years, there has been an increasing interest in the genetic determination of environmental variance. case litter size, variance can be related to capacity animals adapt new conditions, which improve animal welfare. We developed a ten-generation divergent selection experiment on selected one line rabbits for size homogeneity and heterogeneity by measuring intra-doe phenotypic proved that is genetically determined modified selection. Response was 4.5% original per generation. Litter...

Understanding how the host's microbiome shapes phenotypes and participates in host response to selection is fundamental for evolutionists animal plant breeders. Currently, resilience considered a critical step improving sustainability of livestock systems. Environmental variance (V E), within-individual trait, has been successfully used as proxy resilience. Selection reduced V E could effectively shift gut composition; reshape inflammatory response, triglyceride, cholesterol levels; drive...

Variance components were estimated in 3 lines of rabbits selected for litter size at weaning (A, Prat, and V) to test one the assumptions models used selection: that data different parities are repeated measurements same trait. Multiple-trait analyses performed total number kits born (TB), alive (BA), weaned (NW) per litter. Estimates obtained by REML multivariate analyses, including all information selection criteria, under a repeatability model or multiple-trait model, considering first,...

El objetivo de este trabajo es evaluar el desarrollo embrionario 72 horas después la monta dos líneas conejo seleccionadas divergentemente por variabilidad residual del tamaño camada. Las hembras línea alta presentaron un mayor porcentaje inicios mórula (6,0%) que las baja (2,1%). Estos resultados sugieren selección para reducir camada podría tener efecto en temprano.

El objetivo de este trabajo es analizar las características del útero y los fetos a 12 días gesta- ción la coneja. Se utilizaron 55 hembras multíparas se contabilizó tasa ovulación, el peso ovario, longitud cuernos uterinos número embriones implantados. clasifica- ron en vivos o muertos. midió espacio disponible por feto su peso, así como perímetro área placenta fetal materna. La relación fue lineal positiva entre ova- rio ovulación; tracto uterino implantados uterino. probabilidad...

This study aimed to analyze the effect of reducing litter size variability on growth rate, carcass traits, and meat quality in rabbits. Two divergent lines selected by were compared: a line reduce (HO) one increase (HE). All animals fed same commercial diet kept under identical rearing conditions. The HO had lower live weight at weaning compared HE (p ≤ 0.05), but rate was higher than 0.05). Carcass composition similar between lines. No differences pH 45 min 24 h post-mortem found However,...

A divergent selection for resilience was carried out in rabbits over 12 generations. The criterion increased (the HO line) and decreased litter size variability at birth HE line). line (more resilient) shows higher than the (less resilient). sows embryo development line. aim of this work is to investigate plasma organic acid profile both lines mating early gestation order analyze effect by ovulation rate gestation. total 19 18 nonlactating multiparous females from were used. rate, normal...

ABSTRACT Boar spermatozoa are highly susceptible to oxidative damage due their high content of unsaturated fatty acids, which prone disruption by reactive oxygen species (ROS). Excessive ROS can induce lipid peroxidation, DNA fragmentation and impaired enzyme activity, ultimately reducing sperm quality reproductive performance. Wine grape pomace (WGP), a by‐product the winemaking process, is rich in polyphenols, including flavonoids (anthocyanins quercetin), stilbenes (resveratrol) tannins,...

Resilience is the ability of an animal to return soon its initial productivity after facing diverse environmental challenges. This trait directly related welfare and it plays a key role in fluctuations livestock productivity. A divergent selection experiment for variance litter size has been performed successfully rabbits over ten generations. The objective this study was analyse resilience indicators stress disease lines experiment. high line showed lower survival rate at birth than low...

The objective of this study was to obtain heritability estimates for reproductive (litter size at birth, number born alive, litter weaning) and growth traits (individual weaning weight, individual weight the end fattening period), then determine genetic correlation between them in a synthetic rabbit line. A total 805 females, 3242 parities, 18 472 records were measured from 2006 2017. pentavariate animal model used with traits. Heritability ranged 0.025 0.126 0.033 0.059 These showed large...

Abstract A total of 598 F2 does from a cross between the high and low lines selected divergently for uterine capacity during 10 generations were used in candidate gene analysis. The presence major genes affecting number implanted embryos has been suggested capacity. Uterine is main component litter size. progesterone receptor was tested as to determine whether polymorphisms explain differences size its components. Fragments promoter region exons 1–8 amplified sequenced. One SNP found region,...

Abstract Background Environmental variance (V E ) is partly under genetic control and has recently been proposed as a measure of resilience. Unravelling the background V complex traits could help to improve resilience livestock stabilize their production across farming systems. The objective this study was identify genes functional mutations associated with variation in litter size (LS) rabbits. To achieve this, we combined results genome-wide association (GWAS) whole-genome sequencing (WGS)...

We found that virulent hemolysin-producing (Hly+) Listeria monocytogenes strains inhibit antigen processing and presentation when added to macrophages in vitro. A Hly- bacteria caused little or no inhibition. Live Hly+ inhibited of both heat-killed L. ovalbumin. Several observations indicate hemolysin produced by intracellular was responsible for the First, inhibition observed even extracellular were removed after a brief 10-min bacterial uptake period. Second, not prevented addition...

The objective of this work was to study the growth performance, slaughter traits, meat quality, and metabolic profile in rabbits local Algerian population a synthetic line.In total, 120 weaned were used (60 per group). Growth traits recorded from weaning (35 days) (91 days). At slaughter, carcass profiles measured.The line showed heavier total weight faster daily gain than (+15% +19%, respectively), better feed conversion (3.92 vs. 4.81 g/g), cold carcass, perirenal fat (+15%). No...

This note provides a description of software that allows to fit Bayesian genetically structured variance models using Markov chain Monte Carlo (MCMC). The gsevm v.2 program was written in Fortran 90. DOS and Unix executable programs, the user's guide, some example files are freely available for research purposes at http://www.bdporc.irta.es/estudis.jsp. main feature is compute estimates marginal posterior distributions parameters interest. quite flexible, allowing user variety linear level...

The objective of this work was to analyze 3 functional candidate genes for reproduction in 2 lines rabbits divergently selected by uterine capacity. Both were 10 generations. selection then relaxed until the 17th generation, when it compounded 61 and 63 does High Low lines, respectively. We sequenced SCGB1A1 gene, which encodes main protein secreted rabbit uterus seems play an important role implantation. found 6 SNP promoter region cosegregating haplotypes both with similar frequency. also...

A divergent selection experiment for environmental variance of litter size was carried out in rabbits over thirteen generations. The aim this study to evaluate the inflammatory response two lines experiment, order analyse effect on susceptibility diseases after challenging stressful situations, such as 24 h first delivery. total 78 females were used study, 39 from each line. line selected heterogeneity (the high line) showed lower white blood leukocyte count (WBC; −0.87 × 103/µL), percentage...

Abstract Background Environmental variance (V E ) is partially under genetic control, which means that the V of individuals share same environment can differ because they have different genotypes. Previously, a divergent selection experiment for litter size (LS) during 13 generations in rabbit yielded successful response and revealed differences resilience between lines. The aim current study was to identify signatures these lines better understand molecular mechanisms pathways control LS...