Abstract Background Longevity and resilience are two fundamental traits for more sustainable livestock production. These closely related, as resilient animals tend to have longer lifespans. An interesting criterion increasing longevity in rabbit could be based on the information provided by its gut microbiome. The microbiome is essential regulating health plays crucial roles development of immune system. aim this research was investigate if with different longevities microbial profiles. We...

Our objective was to evaluate the correlated responses selection for litter size and its components after 10 generations of divergent uterine capacity (UC). A total 294 intact females from 11th 12th high low UC a cryopreserved control population used (139, 112, 43 females, respectively). Uterine assessed as in unilaterally ovariectomized females. Traits recorded on up five parities were (LS) number born alive (NBA). Laparoscopy performed all at d 12 their second parity, ovulation rate (OR)...

Summary Intramuscular fat (IMF) is one of the main meat quality traits for breeding programmes in livestock species. The objective this study was to identify genomic regions associated with IMF content comparing two rabbit populations divergently selected trait, and generate a list putative candidate genes. Animals were genotyped using Affymetrix Axiom OrcunSNP Array (200k). After control, data involved 477 animals 93 540 SNPs. Two methods used research: single marker regressions adjusted by...

To examine the genetic and phenotypic parameters of uterine capacity its components in rabbits, we performed a divergent selection experiment for capacity. Rabbit does were unilaterally ovariectomized, laparoscopy was at midgestation to count number corpora lutea implanted embryos. Selection on litter size all parities. Genetic estimated by residual maximum likelihood. For most traits, correlations same range. In ovariectomized rabbit does, had low (.34) (−.08) correlation with ovulation...

A study was performed to evaluate the use of unilateral ovariectomy for measurement uterine capacity in rabbits through a comparison relationships between ovulation rate, number implanted embryos, and litter size unilaterally ovariectomized (ULO) intact does. Data from 211 ULO 323 does were analyzed. The animals derived synthetic line previously selected on size. Laparoscopy all during their second gestation 12 d after mating corpora lutea implantation sites recorded. Intact had same...

The aim of this study was to investigate whether uterine capacity (UC) in rabbits related horn length and weight these traits vascular supply were fetal development survival. Data from 48 unilaterally ovariectomized (ULO) does the High 52 ULO Low UC lines a divergent selection experiment on used. Does slaughtered d 25 fifth gestation. line showed higher ovarian (0.08 g, P < 0.05) linked ovulation rate (1 ovum, greater empty horn. There no differences between remaining doe traits. number...

The aim of this work was to determine whether prenatal survival depends on the genotype mother or embryo and identify critical periods for mortality in two lines rabbits divergently selected by high (H) low (L) uterine capacity. Does from H (n = 124) L 115) were slaughtered at 72 h gestation. Embryos recovered gestation transferred oviducts recipient does 23) 19) lines. Each received eight embryos line into one oviduct other. Recipient d 28 No differences found between recovery either...

Abstract A total of 598 F2 does from a cross between the high and low lines selected divergently for uterine capacity during 10 generations were used in candidate gene analysis. The presence major genes affecting number implanted embryos has been suggested capacity. Uterine is main component litter size. progesterone receptor was tested as to determine whether polymorphisms explain differences size its components. Fragments promoter region exons 1–8 amplified sequenced. One SNP found region,...

Intramuscular fat (IMF) content is important for meat production and human health, where the host genetics its microbiome greatly contribute to variation. The aim of this study describe consequences genetic modification IMF by selecting taxonomic composition microbiome, using rabbits from 10th generation a divergent selection experiment (high (H) low (L) lines differ 3.8 standard deviations). altered gut microbiota. Correlated responses were better distinguished at genus level (51 genera)...

The aim of this work is to study early embryo survival and development in 2 lines divergently selected for high low uterine capacity throughout 10 generations. A total 162 female rabbits from the line 133 were slaughtered at 25, 48, or 62 h gestation. There no differences ovulation rate fertilization between any 3 stages Embryo survival, estimated as number normal embryos recovered a constant rate, was similar both 25 48 h. greater [D (posterior mean difference lines) = 0.57 embryos]...

A 10-generation divergent selection experiment for uterine capacity (UC) measured as litter size in unilaterally ovariectomized females was carried out rabbits. total of 2,996 observations on does (up to four parities) recorded. Laparoscopy performed at d 12 their second gestation, and ovulation rate (OR) number implanted embryos (IE) were recorded 735 does. Prenatal survival (PS) assessed UC/OR, embryo (ES) IE/OR, fetal (FS) UC/IE. Genetic parameters genetic trends inferred using Bayesian...

The objective of this work was to analyze 3 functional candidate genes for reproduction in 2 lines rabbits divergently selected by uterine capacity. Both were 10 generations. selection then relaxed until the 17th generation, when it compounded 61 and 63 does High Low lines, respectively. We sequenced SCGB1A1 gene, which encodes main protein secreted rabbit uterus seems play an important role implantation. found 6 SNP promoter region cosegregating haplotypes both with similar frequency. also...

The aim of this work was to evaluate the response 10 generations selection for ovulation rate. Selection based on phenotypic value rate, estimated at d 12 second gestation by laparoscopy. pressure approximately 30%. Line size 20 males and 80 females per generation. Traits recorded were rate gestation, laparoscopy as number corpora lutea in both ovaries; last postmortem; analyzed a single trait including gestation; right left rates; ovulatory difference, difference between litter size, total...

A divergent selection experiment for environmental variance of litter size was carried out in rabbits over thirteen generations. The aim this study to evaluate the inflammatory response two lines experiment, order analyse effect on susceptibility diseases after challenging stressful situations, such as 24 h first delivery. total 78 females were used study, 39 from each line. line selected heterogeneity (the high line) showed lower white blood leukocyte count (WBC; −0.87 × 103/µL), percentage...

The aim of this work was to estimate direct and correlated responses in survival rates an experiment selection for ovulation rate (OR) litter size (LS) a line rabbits (OR_LS). From generation 0 6 (first period), females were selected only second gestation OR estimated by laparoscopy. 7 13 (second 2-stage LS performed. In stage 1, having the greatest at selected. 2, average first 2 parities 1. Total pressure about 30%. had approximately 17 males 75 per generation. Traits recorded as number...

Abstract Uterine capacity (UC), defined as the total number of kits from unilaterally ovariectomized does at birth, has a high genetic correlation with litter size. The aim our research was to identify genomic regions associated size traits through genomewide association study using rabbits divergent selection experiment for UC. A high‐density SNP array (200K) used genotype 181 control population, and low UC lines. Traits included born (TNB), alive (NBA), dead, ovulation rate (OR), implanted...

The aim of this work was to evaluate the correlated responses on survival rates after 10 generations selection for ovulation rate (OR). Selection based phenotypic value estimated at d 12 second gestation by laparoscopy. Traits recorded were litter size (LS), as total number rabbits born per in up 5 parities; OR, corpora lutea both ovaries; implanted embryos (IE), implantation sites; right and left IE (RIE LIE); ovulatory difference (OD), defined between expressed an absolute value;...

Rabbit commercial maternal lines are usually selected for litter size (LS) and paternal growth rate (GR). Line OR_LS was by ovulation (OR) LS to improve more efficiently. In this study, traits of line were evaluated estimating the correlated response on weaning weight (WW), slaughter (SW) GR during fattening period as well their variability (DWW, DSW DGR, respectively). Data analyzed using Bayesian inference methods. Heritability estimates low (0.09, 0.13 0.14 WW, SW GR, respectively)...

The aim of this work was to study the effects genotype dam, embryo, or their interactions on prenatal growth by performing double-reciprocal embryo transfers between two lines rabbits divergently selected for uterine capacity. Females from high (n = 53) and low 48) were slaughtered at 72 h gestation, recovered embryos transferred oviducts recipient does 23) 19) lines. Each doe received eight line into one oviduct other. Recipient d 28 gestation. percentages live fetuses gestation 89.2 74%...

This work evaluated the response to 10 generations of divergent selection for uterine capacity (UC) in rabbits determine whether this was symmetric by contrasting both lines against a cryopreserved control population. Animals came from 13th generation an experiment UC and The two were divergently selected generations, relaxed 11th until generation. Uterine estimated as litter size (LS) unilaterally ovariectomized (ULO) does. To create population, embryos base vitrified stored liquid N2...