Bolívar Samuel Sosa‐Madrid

ORCID: 0000-0002-4269-7593
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Research Areas
  • Genetic and phenotypic traits in livestock
  • Rabbits: Nutrition, Reproduction, Health
  • Ruminant Nutrition and Digestive Physiology
  • Genetic Mapping and Diversity in Plants and Animals
  • Animal Behavior and Welfare Studies
  • Animal Nutrition and Physiology
  • Lipid metabolism and biosynthesis
  • Peroxisome Proliferator-Activated Receptors
  • Meat and Animal Product Quality
  • Animal Ecology and Behavior Studies

Universitat Politècnica de València
2019-2023

Roslin Institute
2023

University of Edinburgh
2023

Summary Intramuscular fat (IMF) is one of the main meat quality traits for breeding programmes in livestock species. The objective this study was to identify genomic regions associated with IMF content comparing two rabbit populations divergently selected trait, and generate a list putative candidate genes. Animals were genotyped using Affymetrix Axiom OrcunSNP Array (200k). After control, data involved 477 animals 93 540 SNPs. Two methods used research: single marker regressions adjusted by...

10.1111/age.12873 article EN cc-by Animal Genetics 2019-11-07

An experiment of divergent selection for intramuscular fat was carried out at Universitat Politècnica de València. The high response in content, after nine generations selection, and a multidimensional scaling analysis showed degree genomic differentiation between the two populations. Therefore, local differences could link regions, encompassing selective sweeps, to trait used as criterion. In this sense, aim study identify regions related through three methods detection signatures generate...

10.1017/s1751731120001263 article EN cc-by-nc-nd animal 2020-01-01

Intramuscular fat (IMF) content and its composition affect the quality of meat. Selection for IMF generated a correlated response on fatty acid composition. The increase is associated with an saturated (SFA) monounsaturated (MUFA) acids, consequently decrease polyunsaturated acids (PUFA). We carried out genome wide association study (GWAS) two rabbit lines divergently selected content, using Bayes B procedure. Association analyses were performed 475 individuals 90,235 Single Nucleotide...

10.3390/ani10112090 article EN cc-by Animals 2020-11-11

Genomic selection uses genetic marker information to predict genomic breeding values (gEBVs), and can be a suitable tool for selecting low-hereditability traits such as litter size in rabbits. However, genotyping costs rabbits are still too high enable prediction selective programs. One method decreasing is the genotype imputation, where parents genotyped at SNP-density (HD) progeny lower SNP-density, followed by imputation HD. The aim of this study was disentangle best strategies with...

10.3390/ani11030803 article EN cc-by Animals 2021-03-13

Abstract Uterine capacity (UC), defined as the total number of kits from unilaterally ovariectomized does at birth, has a high genetic correlation with litter size. The aim our research was to identify genomic regions associated size traits through genomewide association study using rabbits divergent selection experiment for UC. A high‐density SNP array (200K) used genotype 181 control population, and low UC lines. Traits included born (TNB), alive (NBA), dead, ovulation rate (OR), implanted...

10.1111/jbg.12451 article EN Journal of Animal Breeding and Genetics 2019-10-28

Maternal genetic effects (MGE) could affect meat quality traits such as intramuscular fat (IMF) and its fatty acid composition. However, it has been scarcely studied, especially in rabbits. The objectives of the present study were, first, to assess importance MGE on composition by applying a Bayesian maternal animal model two rabbit lines divergently selected for IMF. second objective was identify genomic regions candidate genes that are associated with these offspring, using methods Genome...

10.3390/ani13193071 article EN cc-by Animals 2023-09-30

Monitoring the genetic variance of traits is a key priority to ensure sustainability breeding programmes in populations under directional selection, since selection can decrease variation over time. Studies monitoring changes have typically used long-term data from small experimental selected for handful traits. Here, we large dataset commercial line spread period twenty-three years. A total 2,059,869 records and 2,062,112 animals pedigree were estimations components traits: body weight...

10.3390/ani13213306 article EN cc-by Animals 2023-10-24
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