- Drug-Induced Adverse Reactions
- Pharmaceutical Practices and Patient Outcomes
- Pharmacovigilance and Adverse Drug Reactions
- Diabetes Treatment and Management
- Plant-Microbe Interactions and Immunity
- COVID-19 Clinical Research Studies
- Pharmaceutical studies and practices
- Plant Pathogens and Fungal Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Mosquito-borne diseases and control
- Fungal and yeast genetics research
- Pharmaceutical Economics and Policy
- Blood Pressure and Hypertension Studies
- Tuberculosis Research and Epidemiology
- Autoimmune Bullous Skin Diseases
- Viral Infections and Vectors
- Pneumonia and Respiratory Infections
- Dermatology and Skin Diseases
- Antibiotic Use and Resistance
- Mycorrhizal Fungi and Plant Interactions
- Pneumocystis jirovecii pneumonia detection and treatment
- Drug-Induced Hepatotoxicity and Protection
- Diabetes Management and Research
- Long-Term Effects of COVID-19
- Liver Disease Diagnosis and Treatment
Autonomous Healthcare
2024
All India Institute of Medical Sciences, Deoghar
2022-2024
Sri Balaji Vidyapeeth University
2024
Hospital for Tropical Diseases
2019-2024
Mahatma Gandhi Mission Medical College and Hospital
2022
Creative Commons
2022
Burdwan Medical College & Hospital
2015-2020
Bhabha Atomic Research Centre
2006-2019
Maulana Abul Kalam Azad University of Technology, West Bengal
2017-2018
Texas A&M University
2011-2017
Fusarium species are among the most important phytopathogenic and toxigenic fungi. To understand molecular underpinnings of pathogenicity in genus Fusarium, we compared genomes three phenotypically diverse species: graminearum, verticillioides oxysporum f. sp. lycopersici. Our analysis revealed lineage-specific (LS) genomic regions F. that include four entire chromosomes account for more than one-quarter genome. LS rich transposons genes with distinct evolutionary profiles but related to...
Abstract Background Mycoparasitism, a lifestyle where one fungus is parasitic on another fungus, has special relevance when the prey plant pathogen, providing strategy for biological control of pests protection. Probably, most studied biocontrol agents are species genus Hypocrea / Trichoderma . Results Here we report an analysis genome sequences two atroviride (teleomorph atroviridis ) and virens (formerly Gliocladium , teleomorph ), comparison with reesei jecorina ). These three display...
Abstract In cancer progression, proteolytic enzymes like serine proteases and metalloproteinases degrade the basement membrane enabling tumor cells to invade adjacent tissues. Thus, invasion metastasis are augmented by these enzymes. Simultaneous silencing of uPA MMP9 in breast decreased wound healing, migratory, invasive adhesive capacity cells. After simultaneous down regulation, were seen be arrested cell cycle. There was a remarkable increase expression adhesion molecule E–cadherin,...
An adenylate-cyclase-encoding gene, tac1, of Trichoderma virens, a soil fungus used in the biocontrol plant pathogens, has been cloned and sequenced. The tac1 ORF spanned 7032 bp, encoding protein 2153 aa, which shared an identity 65 % with adenylate cyclase Colletotrichum lagenarium. Deletion through double-crossover homologous recombination, lowered intracellular cAMP levels to below detection limit. mutants showed only 5-6 wild-type growth rate on agar, but grew normally shake culture....
Abstract Artificial intelligence (AI) is a milestone technological advancement that enables computers and machines to simulate human problem-solving capabilities. This article serves give broad overview of the application AI in medicine including current applications future. shows promise changing field medical practice although its practical implications are still their infancy need further exploration. However, not without limitations this also tries address them along with suggesting...
Abstract Although many medical and surgical illnesses are implicated for development of acute respiratory distress syndrome (ARDS), few diseases contribute predominantly as etiology. Pneumonia sepsis the most common causes followed in incidence by aspiration gastric contents, trauma, multiple transfusions, drug overdose. Here, we report a case 15% total body surface area 2 nd -degree thermal burn injury developing severe ARDS, which was managed successfully. Apart from mechanical...
Background: Meropenem, a broad-spectrum carbapenem antibiotic, is widely used to treat severe infections but has been associated with rare cases of drug-induced liver injury, including cholestasis. Recognizing and managing this potential adverse effect essential for ensuring patient safety, particularly in the context prolonged antibiotic use. Case presentation: We report case meropenem-induced cholestasis 57-year-old female history recurrent urinary tract infections. The developed elevated...
SUMMARY GBB1 , a heterotrimeric G‐protein β‐subunit gene, was shown to be key regulator of fumonisin B 1 (FB ) biosynthesis in the maize pathogen Fusarium verticillioides . In this study, we performed functional analyses genes that encode putative RGS (regulators signalling) proteins and PhLPs (phosducin‐like proteins) F. These are known regulate activity by altering intrinsic guanosine triphosphatase (GTPase) activity, which, turn, influences signalling mechanisms control fungal growth,...
Fsr1, a homologue of mammalian striatin, containing multiple protein-binding domains and coiled-coil (CC) domain, is critical for Fusarium verticillioides virulence. In mammals, striatin interacts with proteins to form STRIPAK (striatin-interacting phosphatase kinase) complex that regulates variety developmental processes cellular mechanisms. this study, we identified the key component STRIP1/2 1 2) in F. verticillioides, FvStp1, which Fsr1 vivo. Gene deletion analysis indicates FvStp1 stalk...
This study describes a patient diagnosed as case of bipolar affective disorder complaining bothersome incidence pedal edema 1 month after the initiation atypical antipsychotic regimen with risperidone and quetiapine. All hematological biochemical profiles were found to be normal. On discontinuation risperidone, condition remained unresolved even 2 weeks, progressed reaching her calves. tapering dose quetiapine, she started showing gradual improvement in edematous condition. Quetiapine was...
This study aims to evaluate the dual benefits of dulaglutide in improving glycemic control and reducing knee OA pain.
ABSTRACT Background: Cough is a wearisome and exasperating symptom affecting the daily life of infected patient. due to coronavirus disease 2019 (COVID-19) causes excessive morbidity in human populations globally. Apart from associated with cough, it also enhances transmission this viral infection through droplets. Therefore, curbing cough crucial limit its spread. Patients often administer over-the-counter products antitussive agents, which have no proven benefit. The present study was...
Journal Article Ten clinical pharmacological interventions in routine care to ensure better treatment outcomes Get access Saibal Das, Das Indian Council of Medical Research, Centre for Ageing and Mental Health, Kolkata, IndiaDepartment Global Public Karolinska Institutet, Stockholm, Sweden https://orcid.org/0000-0002-3153-4166 Search other works by this author on: Oxford Academic Google Scholar Shambo Samrat Samajdar, Samajdar Department Clinical Experimental Pharmacology, Calcutta School...