Zhiqiang Zhang

ORCID: 0000-0001-9525-9872
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Research Areas
  • Magnetism in coordination complexes
  • Metal-Catalyzed Oxygenation Mechanisms
  • Microbial Natural Products and Biosynthesis
  • Synthesis and Characterization of Heterocyclic Compounds
  • Genomics and Phylogenetic Studies
  • Bioactive Compounds and Antitumor Agents
  • Medicinal Plants and Bioactive Compounds
  • Plant-Microbe Interactions and Immunity
  • Porphyrin and Phthalocyanine Chemistry
  • Curcumin's Biomedical Applications
  • Lanthanide and Transition Metal Complexes
  • Pharmacological Effects of Natural Compounds
  • Cancer therapeutics and mechanisms
  • Ginseng Biological Effects and Applications
  • Nuclear Receptors and Signaling

Xiamen Medical College
2024-2025

Shandong University
2017

Cancer is one of the deadliest diseases to humanity. There significant progress in treating this disease, but developing some drugs that can fight disease remains a challenge field medical research. Thirteen new 1,2,3-triazole linked tetrahydrocurcumin derivatives were synthesized by click reaction, including 1,3-dipolar cycloaddition reaction baring mono-alkyne with azides good yields, and their vitro anticancer activity against four cancer cell lines, human cervical carcinoma (HeLa), lung...

10.3390/molecules29133010 article EN cc-by Molecules 2024-06-25

Exosomes released from cells have been shown to play an important role in health and disease due their potential application therapy diagnosis. First of all, we extracted the exosome Phascolosoma esculenta, studied lipid lowering antioxidant activity esculenta exosome. It was found that exosomes could significantly decrease accumulation caused by oleic acid, improve triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL-C) low density (LDL-C). The also exhibit activity,...

10.3389/fphar.2025.1560462 article EN cc-by Frontiers in Pharmacology 2025-03-25

Reacting the precursors Eu(dbm) 3 (H 2 O) and Sm(dbm) with enantiopure monobidentate N-donor ligands (L R /L S ), respectively, afforded two chiral Eu III Sm enantiomeric pairs, namely Ln(dbm) )/Ln(dbm) ) (Ln = , D-1 / L-1 Ln =...

10.1039/d4ce01052c article EN CrystEngComm 2024-01-01

Five new polyketides of the ansamycin class, named ansavaricins A–E (<bold>1–5</bold>), together with three known streptovaricins <bold>6–8</bold>, were isolated from <italic>Streptomyces</italic> sp. S012 strain.

10.1039/c6ra27405f article EN cc-by-nc RSC Advances 2017-01-01

Ansamycins are a family of macrolactams characterized by an aromatic chromophore with aliphatic chain (<italic>ansa</italic> chain) connected back to nonadjacent position through amide bond.

10.1039/c7ra00961e article EN cc-by-nc RSC Advances 2017-01-01
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