A5025703063- Anesthesia and Sedative Agents
- Anesthesia and Neurotoxicity Research
- Intensive Care Unit Cognitive Disorders
- Nicotinic Acetylcholine Receptors Study
- Anesthesia and Pain Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Neuroscience and Neuropharmacology Research
- Cancer, Stress, Anesthesia, and Immune Response
- Pharmacological Receptor Mechanisms and Effects
- Alzheimer's disease research and treatments
- Erythropoietin and Anemia Treatment
- Cardiac Arrest and Resuscitation
- Pediatric Pain Management Techniques
- Advanced NMR Techniques and Applications
- Airway Management and Intubation Techniques
- Opioid Use Disorder Treatment
- Respiratory Support and Mechanisms
- Veterinary Pharmacology and Anesthesia
- Cholinesterase and Neurodegenerative Diseases
- Down syndrome and intellectual disability research
- Intraocular Surgery and Lenses
- Antibiotics Pharmacokinetics and Efficacy
- Heme Oxygenase-1 and Carbon Monoxide
- Optical Imaging and Spectroscopy Techniques
- Simulation-Based Education in Healthcare
University of Messina
2011-2024
Istituto Ortopedico Gaetano Pini
2019-2024
Johns Hopkins University
2016
University of Palermo
2008-2012
National Brain Research Centre
2010
Weatherford College
2008
Azienda Ospedaliera Universitaria Policlinico "G. Martino"
2006-2008
Policlinico Universitario di Catania
2008
Martin University
2008
European Society of Anaesthesiology
2007
Treatment for traumatic brain injury (TBI) remains elusive despite compelling evidence from animal models a variety of therapeutic targets. The activation the NLRP3 (Nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3) inflammasome has been proposed as key point in damage associated with TBI. was tested potential target reducing neuronal loss and promoting functional recovery mouse model Male NLRP3-/- (n = 20) wild type 27) mice were used. A closed TBI...
The aims of this study were to evaluate the complications that occur after trauma and characteristics individuals who develop complications, identify potential risk factors increase their incidence, finally investigate relationship between mortality. We did a population-based retrospective patients admitted ICUs level I center. Logistic regression analyses performed determine independent predictors for complications. Of 11,064 studied, 3,451 developed (31.2%). Complications occurred...
The purpose of the study was to determine whether low-high fidelity medical simulation improves learning and long-lasting retention pharmacology knowledge, compared lecture alone, in undergraduate students. Ninety students, before a 45-minute lecture, were randomized into three groups - sham (S), low (LF), high (HF) participate an interactive session. To evaluate immediate retention, 20-item structured questionnaire on inotropic agents administered 90 students after simulation, 3 months...
Object The objectives of this study were to examine whether the systemic administration recombinant human erythropoietin (rHuEPO) and its long-lasting derivative darbepoetin alfa expedited functional recovery in a rat model sciatic nerve injury, compare effects these agents model. Methods Thirty male Sprague–Dawley rats received crush injury left subsequently underwent either placebo treatment, daily injections rHuEPO, or weekly alfa. Results Both rHuEPO effective reducing neurological...
Amyloid-β peptide (Aβ) oligomerization has a profound role in Alzheimer's disease pathophysiology. Biophysical studies have shown that smaller sized inhaled anesthetics promote by inducing perturbation of three critical amino acid res
Oligomerization of amyloid-β peptide (Aβ) is an important stage in Alzheimer's disease. Recently, it has been shown that experimental model, smaller sized (e.g., isoflurane, desflurane, etc.) anesthetics induce Aβ oligomerization. Using state-o