Misako Nishimura

ORCID: 0000-0001-9553-2576
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About
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Research Areas
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Nutrition and Health in Aging
  • Pleural and Pulmonary Diseases
  • Cancer Research and Treatments
  • Pluripotent Stem Cells Research
  • Lung Cancer Diagnosis and Treatment
  • Medical Imaging and Pathology Studies
  • Hormonal Regulation and Hypertension
  • Respiratory Support and Mechanisms
  • Bioactive Compounds and Antitumor Agents
  • Immune cells in cancer
  • SARS-CoV-2 and COVID-19 Research
  • Hematopoietic Stem Cell Transplantation
  • COVID-19 Clinical Research Studies
  • Sinusitis and nasal conditions
  • Phytoestrogen effects and research
  • 3D Printing in Biomedical Research
  • Cancer and biochemical research
  • COVID-19 and Mental Health
  • Long-Term Effects of COVID-19
  • Wound Healing and Treatments
  • Occupational and environmental lung diseases
  • Drug-Induced Adverse Reactions
  • Vascular anomalies and interventions
  • Pediatric health and respiratory diseases

Osaka Metropolitan University
2023-2025

Tokyo Metropolitan University
2023-2025

Tokyo Metropolitan Komagome Hospital
2024-2025

Osaka City University
1995-2023

Hiroshima University
2021

Chronic obstructive pulmonary disease (COPD) is closely related to skeletal muscle dysfunction, and the evaluation of respiratory function has recently been recommended. We aimed investigate effects dysfunction on clinical outcomes. retrospectively reviewed medical records patients with COPD whose strength was measured between June 2015 December 2021. then analysed moderate-to-severe exacerbations after adjusting for confounding factors, including sex, age, forced expiratory volume in 1-s...

10.1111/resp.70003 article EN cc-by-nc-nd Respirology 2025-02-26

To clarify the role of PDGF A-chain in hypertensive vascular hypertrophy spontaneously rats (SHRs), we studied levels gene expression and transcription factors related to smooth muscle cells (VSMCs) SHRs vivo. RNase protection assay situ hybridization showed that mRNA VSMCs were twofold higher than those normotensive Wistar-Kyoto rats. Gel retardation assays Sp1 AP-2 more abundant Treatment with four pharmacologically different species antihypertensive drugs for 2 wk decreased both Sp1, but...

10.1172/jci117762 article EN Journal of Clinical Investigation 1995-03-01

Insufficient evidence has been accumulated regarding associations of heated tobacco products (HTPs) use with coronavirus infection and severity disease 2019 (COVID-19), an ongoing pandemic. We conducted a cross-sectional study using data from internet questionnaire administered in February 2022 to 30,130 individuals the general Japanese population (age range, 16-81 years). Single users HTPs dual combustible cigarettes comprised 5.2% 7.3% respondents, 6.7% 38.0% those infected (n = 1117)....

10.1038/s41598-023-28006-3 article EN cc-by Scientific Reports 2023-02-02

Abstract Introduction Previously, our institution measured peripheral blood CD34 cell counts both pre‐ and post‐peripheral stem harvest (PBSCH), with samples analyzed simultaneously post‐PBSCH. Since 2021, we have pre‐CD34 during PBSCH, adjusting the processed volume based on these results. We retrospectively evaluated how this change impacted cellular therapy. Methods Related healthy donors were included divided into 1‐day 2‐day cohorts. Donors post‐ PBSCH categorized previous current...

10.1111/1744-9987.14202 article EN Therapeutic Apheresis and Dialysis 2024-08-27

Abstract Objective Severe acute respiratory syndrome coronavirus-2 uses angiotensin-converting enzyme-2 as a primary receptor for invasion. This study investigated expression in the sinonasal mucosa of patients with chronic rhinosinusitis, this could be linked to susceptibility severe infection. Methods Ethmoid sinus specimens were obtained from 27 eosinophilic 18 non-eosinophilic rhinosinusitis and controls. The other inflammatory cytokine chemokine messenger RNA levels assessed by...

10.1017/s0022215121001225 article EN cc-by The Journal of Laryngology & Otology 2021-04-30

The fermented soy product ImmuBalance contains many active ingredients and its beneficial effects on some allergic diseases have been reported. We hypothesized that could potential airway inflammation in a murine model of asthma. Mice sensitized challenged with ovalbumin developed inflammation. Bronchoalveolar lavage fluid was assessed for inflammatory cell counts levels cytokines. Lung tissues were examined infiltration mucus hypersecretion. Oral administration significantly inhibited...

10.3390/nu13103380 article EN Nutrients 2021-09-26

Abstract Background The management of intractable secondary pneumothorax poses a considerable challenge as it is often not indicated for surgery owing to the presence underlying disease and poor general condition. While endobronchial occlusion has been employed non-surgical treatment pneumothorax, its effectiveness limited by difficulty locating bronchus leading fistula using conventional techniques. This report details case treated with where combined use transbronchoscopic oxygen...

10.1186/s12890-024-03043-4 article EN cc-by BMC Pulmonary Medicine 2024-06-05

<b>Introduction:</b> Transbronchial cryobiopsy enables high-quality sample collection around the probe tip. Meanwhile, existing cryoprobes have less flexibility and a higher risk of bleeding. The 1.1-mm cryoprobe addresses these problems allows specimens to be directly retrieved through working channel thin bronchoscope. <b>Aim:</b> We evaluated diagnostic utility safety non-intubated using added conventional biopsy for diagnosing peripheral pulmonary lesions (PPLs). <b>Methods:</b> data...

10.1183/13993003.congress-2023.pa468 article EN 2023-09-09
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