- Bone health and treatments
- Oral and gingival health research
- HIV/AIDS oral health manifestations
- Bone and Joint Diseases
- Viral-associated cancers and disorders
- Oral Health Pathology and Treatment
- Parvovirus B19 Infection Studies
- Oral health in cancer treatment
- Cancer Diagnosis and Treatment
- Hemophilia Treatment and Research
- Bone Tumor Diagnosis and Treatments
- Platelet Disorders and Treatments
- Immunodeficiency and Autoimmune Disorders
- Oral and Maxillofacial Pathology
- Herpesvirus Infections and Treatments
- Radiopharmaceutical Chemistry and Applications
- Tumors and Oncological Cases
- Cutaneous lymphoproliferative disorders research
- Head and Neck Cancer Studies
- Blood groups and transfusion
- Poxvirus research and outbreaks
- Syphilis Diagnosis and Treatment
- Cancer-related gene regulation
- Pituitary Gland Disorders and Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
Sapienza University of Rome
2019-2021
Policlinico Umberto I
2017-2019
Ospedale Regina Margherita
2012
Fondazione Gimema Onlus
2009
Eastman Dental Hospital
2008
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2008
CTO Hospital
2005
University of Florence
1988-1994
University of California, Los Angeles
1993
University of Houston
1993
The aim of this study was to compare retrospectively the effect three different treatment protocols on healing outcome in patients with established medication-related osteonecrosis jaw (MRONJ).A total 34 MRONJ were recruited from Department database and divided according a group (G1) two control groups (G2 G3). G1 treated antibiotic therapy, surgery, leukocyte- platelet-rich fibrin (L-PRF), photobiomodulation; G2 therapy surgery; G3 photobiomodulation. Various clinical variables analyzed...
Langerhans cell histiocytosis (LCH) is a rare disorder characterized by high proliferation of dendritic cells. LCH solitary or multifocal disease that primarily involves bone tissue and often affects children young men. A 29 years-old Caucasian man was referred to the Oral Surgery Unit George Eastman Hospital - Umberto I teaching hospital, with third degree mobility teeth belonging second, fourth quadrant. Panoramic radiograph showed multiple radiolucent areas well demarcated borders on...
Bisphosphonates (BPs) are used intravenously to treat cancer-related conditions for the prevention of pathological fractures. Osteonecrosis jaw (BRONJ) is a rare complication reported in 4–15% patients. We studied, retrospectively, 55 patients with multiple myeloma or Waldenstrom's macroglobulinemia followed up from different haematological departments who developed BRONJ. All were treated BPs bone lesions and/or The most common trigger BRONJ was dental alveolar surgery. After median...
Abstract Clinical and histologic morphology of oral hairy leukoplakia in 85 HIV‐positive patients were studied. Differential diagnosis comparison with the normal lingual buccal epithelium from both HIV‐negative patients, other tongue conditions was also examined. Oral lesions located on lateral borders showed a corrugated/hairy aspect majority cases. Hyperparakeratosis, hyperplasia/acanthosis, papillated epithelial surface common findings. A parakeratin band ballooning cells present 60% 99%...
To retrospectively assess the effectiveness and safety of customized hemostatic protocols using a plasma-derived, von Willebrand Factor (VWF)-containing VIII concentrate (pdVWF/FVIII) in disease (VWD) patients undergoing dental invasive procedures.Protocol for each patient was drawn up by Blood Unit based on VWD type, severity, type treatment. pdFVIII/VWF infusions doses were registered at 30-60 min before intervention (t0) 12-24-36-48-72 h after (t12-t72) to day 7. Any peri- or...
Key Clinical Message These cases of people with hemophilia (PWH) illustrate the importance understanding patient's expectations and desires adapting treatment to meet these needs, in addition traditional clinical targets. Population PK modeling FVIII products improved profiles provide opportunity individualize care improve long‐term outcomes.
Medication-related osteonecrosis of the jaws (MRONJ) has multiple exogenous and endogenous risk factors. The MRONJ associated with anti-resorptive drugs (Bisphosphonates Denosumab) was reviewed in oncological osteoporotic patients referred to Department Oral Maxillo-Facial Sciences, Sapienza University Rome (Italy), since January 2019 2021. incidence analyzed according local (dental extraction), systemic factors (diabetes, steroid, ecc), medication type, drug treatment duration. intake...