A5080741394- Oral Health Pathology and Treatment
- Laser Applications in Dentistry and Medicine
- Oral and Maxillofacial Pathology
- Head and Neck Cancer Studies
- Bone health and treatments
- Cancer Diagnosis and Treatment
- Oral health in cancer treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Bone and Joint Diseases
- Oral and gingival health research
- Endodontics and Root Canal Treatments
- Dermatologic Treatments and Research
- Dental Radiography and Imaging
- Vascular Malformations and Hemangiomas
- Dental Anxiety and Anesthesia Techniques
- Tumors and Oncological Cases
- Photodynamic Therapy Research Studies
- Head and Neck Surgical Oncology
- Dental materials and restorations
- Bone Tumor Diagnosis and Treatments
- Salivary Gland Disorders and Functions
- Dental Implant Techniques and Outcomes
- Respiratory and Cough-Related Research
- Cancer-related molecular mechanisms research
- Reconstructive Surgery and Microvascular Techniques
Sapienza University of Rome
2016-2025
Policlinico Umberto I
2017-2024
National Medical Research Center of Dentistry and Maxillofacial Surgery
2013
The aim of this study was to compare retrospectively the effect three different treatment protocols on healing outcome in patients with established medication-related osteonecrosis jaw (MRONJ).A total 34 MRONJ were recruited from Department database and divided according a group (G1) two control groups (G2 G3). G1 treated antibiotic therapy, surgery, leukocyte- platelet-rich fibrin (L-PRF), photobiomodulation; G2 therapy surgery; G3 photobiomodulation. Various clinical variables analyzed...
The aim of this study was to compare the peripheral bone damage induced by different cutting systems. Four devices were tested: Er:YAG laser (2.94 mm), Piezosurgery, high-speed drill and low-speed drill. Forty-five sections, divided into 9 groups according parameters, taken from pig mandibles within 1 h post mortem. Specimens fixed in 10% buffered formalin, decalcified cut thin sections. parameters analyzed: precision, depth incision, carbonization presence fragments. For statistical...
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is an adverse side effect associated with bisphosphonate (BP) therapy, especially when parenteral BP administration used. Patients affected by BRONJ present wide areas exposed necrotic bone, particularly after surgical oral procedures. The main symptom pain that poorly controlled common analgesic drugs. Recently, many studies have pointed to beneficial low-level laser therapy (LLLT) in reduction for pathological conditions. purpose this...
MRONJ (medication related osteonecrosis of the jaws) is a well-known side effect certain drugs, which are used to influence bone metabolism for cure osteo-metabolic or cancer diseases. The aim this study assess quality life (QOL) under physical and mental point view in patients affected by compared with general population.The has been accomplished through administration SF-12 questionnaire: 30 group were evaluated.Significant differences based on level education age subjects, location...
The aim of the study is to observe retrospectively correlation between Oral Squamous Cell Carcinoma (OSCC) and risk factors; including tobacco, alcohol Family History Cancer (FHC). A total 478 patients were included from database Department Sciences Maxillofacial Surgery, Sapienza University Rome. Test Group (TG) consisted 239 with a confirmed diagnosis OSCC. Control (CG) without history and/or oral cancer. logistic regression models used calculate adjusted Odd Ratios (ORs) associated...
The aim of this study is to evaluate the bone scintigraphy (BS) and positron emission tomography (PET) in early diagnosis medication-related osteonecrosis jaws (MRONJ) their possible use identification patients at risk for MRONJ. Thirty-one treated with ONJ-related drugs who had undergone BS or PET evaluation lesions were included study. each patient divided into four areas. For area, presence pathological tracer uptake was evaluated related eventual MRONJ development. Sensitivity,...
Kaposiform Hemangioendothelioma (KHE) is a rare, locally aggressive vascular tumor with histological similarities to Kaposi’s Sarcoma. It often presents in infancy or early childhood, rarely affecting adults. The most common sites include the skin, retroperitoneum, and less frequently, head, neck, mediastinum. KHE seldom self-regressing, distant metastases are though 70% of cases may develop Kasabach-Merritt Syndrome (KMS), severe coagulopathy marked by thrombocytopenia high mortality due...
Despite extensive research, the exact cause of oral lichenoid lesions remains unknown. The chronic inflammatory tissue reaction mediated by T cells is basis etiological process. However, often occur in presence certain drugs. Our aim was to conduct a preliminary retrospective study assess correlation between administration statins or HMG-inhibitor CoA reductase, which are commonly used for treating hypercholesterolemia, and sartans blockers angiotensin II receptor, hypertension, relation...
Introduction The association between diabetes mellitus (DM) and oral lichen planus (OLP) has been widely reported. However, most of the studies focused on epidemiological aspects shared inflammatory pathways, with few exploring consequences this clinical course OLP. study aims to retrospectively observe impact DM presentation management strategy Methods A total 97 OLP patients were retrieved from Department database. distributed into two groups: “test group” ( n = 47) without “control 50)....
Extraction of third molars is the most common surgical procedure performed in oral surgery on a daily basis and, despite skills and expertise, complications may occur. Complications observed during or after molar removal include pain, swelling, bleeding, infection, sinus perforation nerve damage. Fortunately, with proper management good technique, incidence such events low. Subcutaneous emphysema associated dental extraction occurs when air from high-speed handpiece forced into soft tissue...
It is important to identify factors that affect primary stability of orthodontic mini-implants because it determines the success treatment. We assessed mini-implant (initial mechanical engagement with bone) placed in pig jaws. also insertion failure rate (mini-implant fracture, root contact). A total 80 taper-shaped (Absoanchor® Model SH1312-6; Dentos Inc., Daegu, Korea) 6 mm long a diameter 1.1 were used. Bone decortication was made before by means three different methods: Group G1: Er:YAG...
The aim of this study is to observe the influence Medication-Related Osteonecrosis Jaw (MRONJ) on physical and mental conditions cancer patients using a Quality Life (QoL) questionnaire during regular dental practice measures. Twenty (8 males 12 females) with established MRONJ were enrolled in "MoMax" (Oral Medicine Maxillofacial) project Department Oral Sciences Maxillofacial Surgery at "Sapienza" University Rome, included study. 12-item Short Form Survey was used evaluate QoL. Statistical...
Abstract Objectives Oral lichen planus with exclusive keratotic reticular, papular, and/or plaque-like lesions (K-OLP) is a clinical pattern of OLP that may be associated complex symptomatology and psychological alteration. The aim the study was to evaluate prevalence anxiety (A) depression (D) in patients K-OLP, analyzing potential predictors which can affect mental health status. Methods Three hundred K-OLP versus 300 healthy controls (HC) were recruited 15 Italian universities. Numeric...
This study aims to retrospectively assess the potential risk of malignant transformation in patients with diagnosed oral lichen planus (OLP) between 2015 and 2022, evaluate influence different factors. The department's database medical records from 2022 were searched for a confirmed diagnosis OLP based on both clinical histological parameters. A total 100 (59 females 41 males) found mean age 64.03 years. In considered period, percentage was 1.6%, while squamous cell carcinoma (OSCC) 0.18%....
Objective: The purpose of this study was to compare secondary intention healing oral soft tissues after laser surgery with and without the use a compound containing amino acids sodium hyaluronate. Background data: Sodium hyaluronate has been successfully used in medicine promote healing. It not studied laser-produced wounds. Materials methods: Excisional biopsy performed potassium-titanyl-phosphate (KTP) (532 nm, SmartLite, DEKA, Florence, Italy) 49 patients divided into two groups. In group...