Lorenzo Azzi

ORCID: 0000-0003-2532-7651
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About
Contact & Profiles
Research Areas
  • Salivary Gland Disorders and Functions
  • Oral Health Pathology and Treatment
  • Oral and Maxillofacial Pathology
  • SARS-CoV-2 and COVID-19 Research
  • Dental Research and COVID-19
  • SARS-CoV-2 detection and testing
  • Dental Implant Techniques and Outcomes
  • COVID-19 Clinical Research Studies
  • COVID-19 diagnosis using AI
  • Cancer Diagnosis and Treatment
  • Oral and gingival health research
  • Dermatological and COVID-19 studies
  • Ethics in medical practice
  • Animal Virus Infections Studies
  • Bacterial Infections and Vaccines
  • Orthodontics and Dentofacial Orthopedics
  • Oral microbiology and periodontitis research
  • Respiratory and Cough-Related Research
  • Autoimmune and Inflammatory Disorders
  • Bone Tumor Diagnosis and Treatments
  • Dental materials and restorations
  • Periodontal Regeneration and Treatments
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Tumors and Oncological Cases
  • Cancer Immunotherapy and Biomarkers

University of Insubria
2013-2024

Azienda Socio Sanitaria Territoriale Lariana
2020-2024

ATS Sardegna (Italy)
2024

Aziende Socio Sanitarie Territoriale dei Sette Laghi
2021-2022

Fondazione Audiologica Varese
2013-2021

Mito Saiseikai General Hospital
2021

Ospedale di Circolo e Fondazione Macchi
2014-2020

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2015

University of Milan
2014

New York Proton Center
2013

This study analyzed salivary samples of COVID-19 patients and compared the results with their clinical laboratory data.

10.1016/j.jinf.2020.04.005 article EN cc-by-nc-nd Journal of Infection 2020-04-14

Although the BNT162b2 COVID-19 vaccine is known to induce IgG neutralizing antibodies in serum protecting against COVID-19, it has not been studied detail whether could generate specific immunity at mucosal sites, which represent primary route of entry SARS-CoV-2.

10.1016/j.ebiom.2021.103788 article EN cc-by-nc-nd EBioMedicine 2021-12-23

The diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection relies on the detection viral RNA by real-time reverse transcription polymerase chain reaction (rRT-PCR) performed with respiratory specimens, especially nasopharyngeal swabs. However, this procedure requires specialized medical personnel, centralized laboratory facilities, and time to provide results (from several hours up 1 d). In addition, there is a non-negligible risk transmission for operator who...

10.1177/0022034520969670 article EN cc-by Journal of Dental Research 2020-10-31

<h3>Importance</h3> Since February 2020, coronavirus disease 2019 (COVID-19) has spread rapidly all over the world, with an epidemiological cluster in Lombardy, Italy. The viral communicability may be mediated by various body fluids, but insufficient information is available on presence of virus human tears. <h3>Objectives</h3> To investigate rate severe acute respiratory syndrome 2 (SARS-CoV-2) tears collected from patients COVID-19 means real-time reverse transcriptase–polymerase chain...

10.1001/jamaophthalmol.2020.5464 article EN JAMA Ophthalmology 2021-03-04

Abstract We report an imported case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant P.1 detected in asymptomatic traveler who arrived Italy on indirect flight from Brazil. This shows the risk for introduction SARS-CoV-2 variants flights and need continued surveillance.

10.3201/eid2704.210183 article EN cc-by Emerging infectious diseases 2021-02-10

We report two cases of COVID-19 showing negative respiratory swabs but positive salivary samples at the same time. These findings rise concern about how to manage these patients before hospital discharging, thus avoiding contagion among their family members or a second coronavirus wave once lockdown is over.

10.1111/odi.13368 article EN Oral Diseases 2020-04-25

Optimal aesthetic implant restoration is a combination of visually pleasing prosthesis and adequate surrounding peri-implant soft tissue architecture. This study describes the influence residual buccal bone thickness (BBT), measured at time placement, on maturation during three years follow-up. Seventy-eight implants were enrolled in present study. The BBT was assessed surgical stage each case assigned to Group 1 (BBT values ≤0.5 mm), 2 >0.5 <1.5 or 3 ≥1.5 mm). Only native healed sites...

10.3390/ma13030511 article EN Materials 2020-01-21

Background Burning mouth syndrome remains a puzzling condition. One symptom commonly associated with the burning sensation is xerostomia. The current study measured basal and stimulated salivary flow in group of patients. Methods Three groups patients were recruited: 44 patients, 27 oral lichen planus 40 healthy We chose to measure three using ‘spitting’ method. Thus, asked spit every minute for 5 min. Afterwards, they repeat procedure second time, but drop citric acid was positioned on...

10.1111/jop.12240 article EN Journal of Oral Pathology and Medicine 2014-08-26

Antibody-dependent enhancement (ADE) of severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) infection has been hypothesized. However, to date, there no in vitro or vivo evidence supporting this. Cross-reactivity exists between SARS CoV-2 and other Coronaviridae for both cellular humoral immunity. We show here that IgG against nucleocapsid protein alphacoronavirus NL63 229E correlate with the World Health Organization’s (WHO) clinical severity score ≥ 5 (incidence rate ratios was...

10.3390/life11040298 article EN cc-by Life 2021-04-01

Abstract Objectives Oral lichen planus with exclusive keratotic reticular, papular, and/or plaque-like lesions (K-OLP) is a clinical pattern of OLP that may be associated complex symptomatology and psychological alteration. The aim the study was to evaluate prevalence anxiety (A) depression (D) in patients K-OLP, analyzing potential predictors which can affect mental health status. Methods Three hundred K-OLP versus 300 healthy controls (HC) were recruited 15 Italian universities. Numeric...

10.1007/s00784-023-04909-3 article EN cc-by Clinical Oral Investigations 2023-02-14

The aim of this study was to evaluate the influence bone quality, drilling technique, implant diameter, and length on insertion torque (IT) resonance frequency analysis (RFA) a prototype-tapered with knife-edge threads. investigators hypothesized that IT would be affected by variations in quality protocol, whereas RFA less influenced such variables. implemented an vitro experiment which prototype inserted different testing conditions into rigid polyurethane foam blocks. independent variables...

10.1563/aaid-joi-d-19-00145 article EN Journal of Oral Implantology 2020-03-03

Oral Squamous Cell Carcinoma (OSCC) is the most common malignant tumor of oral cavity. Despite recent advances in field cancer therapy, including introduction immunotherapeutic approaches, 5-year survival rate remains steadily assessed around 50%. Thus, there an urgent need for new therapeutic strategies. After characterization immune phenotype three human OSCC cell lines (CAL-27, SCC-25, and SCC-4) one mouse line (MOC2) showing their similarities to resected patient tumors, we explored...

10.3389/fimmu.2024.1387835 article EN cc-by Frontiers in Immunology 2024-07-05

Objectives: Torquetenovirus (TTV) and Redondovirus (ReDoV) are the most prevalent viruses found in human respiratory virome viral metagenomics studies. A large-scale epidemiological study was performed to investigate their prevalence loads saliva samples according SARS-CoV-2 status. Methods: Saliva from 448 individuals (73% negative 27% positive) aged 23–88 years were tested. TTV determined by specific qualitative quantitative real-time PCRs, respectively. sub-cohort of 377 subjects...

10.3390/v14112482 article EN cc-by Viruses 2022-11-09
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