A5071070151- Hydrogels: synthesis, properties, applications
- Electrospun Nanofibers in Biomedical Applications
- Wound Healing and Treatments
- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Osteoarthritis Treatment and Mechanisms
- Bone Tissue Engineering Materials
- Antibiotic Resistance in Bacteria
- Dendrimers and Hyperbranched Polymers
- Graphene and Nanomaterials Applications
- Metal-Organic Frameworks: Synthesis and Applications
- Bone health and treatments
- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Dental Implant Techniques and Outcomes
- Sulfur Compounds in Biology
- Tissue Engineering and Regenerative Medicine
- Silk-based biomaterials and applications
- Endodontics and Root Canal Treatments
- Supramolecular Self-Assembly in Materials
- Generative Adversarial Networks and Image Synthesis
- Supply Chain Resilience and Risk Management
- Hydrogen's biological and therapeutic effects
- Face recognition and analysis
- Phytochemistry and biological activity of medicinal plants
Vietnam Academy of Science and Technology
2021-2025
Ajou University
2019-2022
National Institute Of Hygiene And Epidemiology
2021-2022
Vinh University
2022
Government of the Republic of Korea
2020
Konkuk University
2011
In situ nitric oxide generation from copper-containing hydrogel enhances anti-inflammatory, cell migration, and angiogenic processes for promoted wound healing.
Biphasic calcium phosphate (BCP) is a bioceramic widely used in hard tissue engineering for bone replacement. BCP consists of β-tricalcium (β-TCP) - highly soluble and resorbable phase hydroxyapatite (HA) stable phase, creating balance between solubility resorption, optimally supporting cell interactions growth. The β-TCP/HA ratio significantly affects the solubility, cellular response, with higher β-TCP increasing resorption due to its solubility. commonly synthesized by calcining...
ABSTRACT Hydrogen sulfide (H₂S) plays a critical role in regulating various pathological processes, such as protecting cells from injury and promoting tissue regeneration, making it focus of therapeutic applications. However, the unpredictable release H₂S donors limit its clinical use. In this study, novel delivery system was developed by encapsulating 5‐aminopyridine‐2‐thiocarboxamide (APTC), small‐molecule donor, into gelatin‐Pluronic (GP) thermosensitive hydrogel. The GP hydrogel...
(1) Background: Knee cartilage injury is at the top of rising concerns among bone and joint disorders patients. Autologous chondrocyte implantation (ACI) widely used to approach knee deterioration. Integrating autologous chondrocytes periosteal patches aids in forming new cartilage-like tissue lesion area. This study uses a novel cell source from one-day-old porcine fabricate bio-membrane as substitute for membranes techniques treating injuries. (2) Methods: Cells isolated were identified...
With the rising incidence of cancer, chemotherapy has become a widely used treatment approach. However, use anticancer drugs such as doxorubicin (DOX) poses significant long-term risks due to its nonspecific distribution and severe side effects. Therefore, developing nanoparticle-based drug delivery system (DDS) that enhances bioavailability DOX specifically cancer cells is crucial while minimizing effects on normal cells. This study employed zeolitic imidazolate framework-8 (ZIF-8) DDS...
(1) Autologous chondrocyte implantation (ACI) is a prominent method for treating cartilage damage, but periosteal patches can cause leakage. This study evaluates the potential of decellularized membrane derived from cell-produced extracellular matrix 1-day-old porcine (pcECM-DM) to act as substitute patches. (2) The interaction between young rabbit cells and pcECM-DM was assessed through cytotoxicity, differentiation, cell viability, migration, adhesive ability. Rabbit cells, cultivated...
(1) Background: Knee cartilage injury is at the top of rising concerns among bone and joint disorder patients. Autologous chondrocyte implantation (ACI) widely used to approach knee deterioration. Integrating autologous chondrocytes periosteal patches aids in forming new cartilage-like tissue lesion area. This study uses a novel cell source from one-day-old porcine fabricate biomembrane as substitute for membranes techniques treating injuries. (2) Methods: Cells isolated were identified...
The impairment of regenerative processes induced by high blood-glucose level (hyperglycemia) and excessive reactive oxygen species (ROS) contributes to the diabetic complication progression development. In this study, an injectable, in situ crosslinkable chitosan hydrogel with ROS-scavenging capability was developed conjugating gallic acid onto backbone (CGA). We hypothesized that serves as both antioxidant crosslinking moieties form means enzymatic horseradish peroxidase (HRP). rapid...
ABSTRACT The advancement of therapeutic gas treatment has significantly impacted on the biomaterial field, with nitric oxide (NO) gaining attention for its safety, multifunctionality, and role in regulating biological processes. Thus, this study introduces a novel biocatalytic NO‐generating situ forming hydrogel (GTA/Cu) to address wound‐related issues, fabricated through simple, one‐step process by incorporating copper ions (Cu 2+ ) into tannic acid‐conjugated gelatin (GTA). Herein, Cu...
ABSTRACT This research focused on developing a multi‐targeted, stimuli‐responsive drug delivery system by integration of iron oxide nanoparticles (IONPs) and Cholesterol‐Polyethylene glycol‐Folic acid conjugate (CPF) to enhance the poorly water‐soluble drugs. Oleic (OA) coated (OCION) were synthesized subsequently functionalized with CPF form OCION–CPF. Quercetin (QCT), model soluble drug, was encapsulated into using thin film method. Analytical techniques, including dynamic light scattering...
CaO<sub>2</sub> catalyzes the formation of <italic>in situ</italic> hydrogels with multifunctional properties through its decomposition into H<sub>2</sub>O<sub>2</sub>, O<sub>2</sub>, and Ca<sup>2+</sup> ions.
Injectable hydrogels offer a wide range of attractive benefits in drug delivery applications, such as non-invasive administration, easy incorporation and locally controlled release at the target sites. Herein, we designed simple efficient method to prepare injectable composed gelatin cyclodextrin (CD) for high loading capacity hydrophobic drugs. The were formed by thiol-functionalized (GSH) βCD-vinyl sulfone (βCD-VS) cross-linker, via thiol-ene “click” chemistry. Hydrogels comprising...
Horseradish peroxidase-catalyzed injectable gelatin hydrogels have attracted much attention in various biomedical fields because of their processability, biodegradability, and excellent biocompatibility promoting cell adhesion proliferation. However, derivatives are mainly obtained from mammalian sources (porcine, bovine) with thermal gelation at room temperature, leading to the potential problems biofabrication applications. Here, we introduce a novel fish derivative that can be easily...
Mesoporous silica nanoparticles (MSNs) have been demonstrated as a promising candidate in drug delivery applications. With the ambition of enhancing their loading capacity and controlled release, this innovative study, MSNs were tailored with polyamidoamine (PAMAM) dendrimers thereby exerting advantageous properties onto surface nanoplatforms. prepared by Stöber’s method, sequentially functionalised amine groups, respectively grafted PAMAMs layer-by-layer. Morphology characterisation carried...
Abstract This study reports for the first time usage of polyethylene glycol (PEG) as capping agent to control mesoporous shell thickness hollow silica nanoparticles (HMSN)—a promising nanocarrier. HMSN was synthesized with hard template method and PEG different molecular weights concentrations would be added at coating. The samples dSiO 2 @MSN without were analyzed DLS, field‐emission scanning electron microscopy, Brunauer–Emmett–Teller Barrett–Joyner–Halenda characterize their shells....