A5056396801- Tuberculosis Research and Epidemiology
- Pneumonia and Respiratory Infections
- Adolescent Sexual and Reproductive Health
- HIV/AIDS Research and Interventions
- Pneumocystis jirovecii pneumonia detection and treatment
- Poverty, Education, and Child Welfare
- Global Maternal and Child Health
- COVID-19 epidemiological studies
- Infectious Diseases and Tuberculosis
- Helicobacter pylori-related gastroenterology studies
- Gastric Cancer Management and Outcomes
- Child Nutrition and Water Access
- Data-Driven Disease Surveillance
- SARS-CoV-2 and COVID-19 Research
- Evolution and Genetic Dynamics
- Mycobacterium research and diagnosis
- HIV/AIDS Impact and Responses
- Sex work and related issues
- COVID-19 Clinical Research Studies
- Gastrointestinal disorders and treatments
- Healthcare Systems and Reforms
- Health Systems, Economic Evaluations, Quality of Life
- Problem and Project Based Learning
- HIV, Drug Use, Sexual Risk
- Schizophrenia research and treatment
Imperial College London
2022-2023
University of Sheffield
2020-2022
The University of Melbourne
2016-2021
Peter Doherty Institute
2018-2021
Jimma University
2021
Hawassa University
2012-2016
Ethiopia has one of the highest maternal mortality in world. Institutional delivery is key intervention reducing and complications. However, uptake service remained low factors which contribute to this appear vary widely. Our study aims determine magnitude identify affecting at health institution two districts Ethiopia. A community based cross sectional household survey was conducted from January February 2012 12 randomly selected villages Wukro Butajera northern south central parts...
Abstract Tuberculosis (TB) killed more people globally than any other single pathogen over the past decade. Where surveillance is weak, estimating TB burden estimates uses modeling. In many African countries, increases in HIV prevalence and antiretroviral therapy have driven dynamic epidemics, complicating estimation of burden, trends, potential intervention impact. We therefore develop a novel age-structured transmission model incorporating evolving demographic, effects, calibrate to...
Tuberculosis (TB) and HIV co-infection remains a major public health problem. In spite of different initiatives implemented to tackle the disease, many countries have not reached TB control targets. One attributing reasons for this failure is infection with HIV. This study aims determine effect on survival patients. A retrospective cohort was employed compare between positive negative patients (370 each) during an eight month directly observed treatment short-course (DOTS) period. patient's...
The measurement of condom use self-efficacy requires contextually suitable, valid and reliable instruments due to variability the scale across nations with different cultural ethnic backgrounds. This study aims construct a suitable Ethiopia (CUSES-E), based on original developed by Brafford Beck. A cross-sectional was conducted random sample 492 students at Hawassa University. self-administered questionnaire containing 28 items from used collect data. Principal Component Analysis (PCA)...
Reported tuberculosis (TB) incidence globally continues to be heavily influenced by expert opinion of case detection rates and ecological estimates disease duration. Both approaches are recognised as having substantial variability inaccuracy, leading uncertainty in true TB other such derived statistics. We developed Bayesian binomial mixture geospatial models estimate rate (CDR) Ethiopia. In these the underlying was formulated a partially observed Markovian process following mixed Poisson...
To describe the distribution of tuberculosis (TB) and its drivers in Sheka Zone, a geographically remote region Ethiopia.We collected data on TB patients treated from 2010 to 2014 Zone. Predictors incidence were determined using multivariate generalised linear regression model.We found significant spatial autocorrelation by kebele (the smallest administrative geographical subdivision Ethiopia) (Moran's I = 0.3, P < 0.001). The average per ranged 0 453 100 000 population year, was...
Abstract Globally, men have higher tuberculosis (TB) burden but the mechanisms underlying this sex disparity are not fully understood. Recent surveys of social mixing patterns established moderate preferential within-sex in many settings. This assortative could amplify differences from other causes. We explored impact and factors differentially affecting disease progression detection using a sex-stratified deterministic TB transmission model. influence assortativity at disease-free endemic...
Determining the extent of seropositivity SARS-CoV-2 antibody has potential to guide prevention and control efforts. We aimed determine seroprevalence among individuals aged above15 years residing in congregate settings Dire Dawa city administration, Ethiopia.We analyzed COVID-19 data on 684 from a community based cross-sectional survey conducted above 15 June July 30, 2020. Data were collected using interview blood sample collection. Participants asked about demographic characteristics,...
Pakistan's national tuberculosis control programme (NTP) is among the many programmes worldwide that value importance of subnational (TB) burden estimates to support disease efforts, but do not have reliable estimates. A hackathon was thus organised solicit development and comparison several models for small area estimation TB. The TB launched in April 2019. Participating teams were requested produce district-level bacteriologically positive prevalence adults (over 15 years age) 2018. NTP...
Geospatial tuberculosis (TB) hotspots are hubs of TB transmission both within and across community groups. We aimed to quantify the extent which these account for spatial spread in a high-burden setting. developed spatially coupled models from geographical distant regions rural Ethiopia. The population was divided into three 'patches' based on their proximity hotspots, namely adjacent remote regions. were fitted 5-year notification data aggregated by metapopulation structure. Model fitting...
Tuberculosis (TB) exhibits considerable spatial heterogeneity, occurring in clusters that may act as hubs of community transmission. We evaluated the impact an intervention targeting TB hotspots a rural region Ethiopia. To evaluate targeted active case finding (ACF), we used spatially structured mathematical model has previously been described. From equilibrium, simulated hotspot-targeted strategy (HTS) on incidence ten years from commencement and associated cost-effectiveness. HTS was also...
There is concern about the increasing rates of loss to follow-up (LTFU) among pre-antiretroviral therapy (pre-ART) patients in Ethiopia. Little information available regarding time when pre-ART are lost country. This study assessed LTFU occurs as well associated factors adults enrolled care an Ethiopian rural hospital. Data all adult at Sheka Zonal Hospital between 2010 and 2013 were reviewed. Patients considered if they failed keep scheduled appointments for more than 90 days. The Cox...
Ethiopia has reduced maternal mortality from 871 to 412 per 100,000 live births between 2000 and 2016. In 2019, under-5 rates in were 55 deaths 1,000 births. Benishangul Gumuz was the second-largest region rate (98/1,000 births) country. Maternal child health care service uptake is an important indicator of outcomes. This study aimed at exploring major barriers Assosa Zone. conducted Bambasi, Menge, Sherkole districts Zone July 17 August 31/2019. The explored life experience participants...
Voluntary counseling and testing (VCT) is a cost-effective tool to prevent control human immunodeficiency virus (HIV)/acquired immodeficiency syndrome. Community conversation (CC) community-based strategy meant enhance the community utilization of VCT. However, role CC in VCT service uptake has not yet been evaluated.This study was conducted compare between rural communities with well performance poor Shebedino woreda.A cross-sectional comparative 2010 among 462 selected adults age bracket...
ABSTRACT Globally, men have higher tuberculosis (TB) burden but the mechanisms underlying this sex disparity are not fully understood. Recent surveys of social mixing patterns established moderate preferential within-sex in many settings. This assortative could amplify differences from other causes. We explored impact and factors differentially affecting disease progression detection using a sex-stratified deterministic TB transmission model. influence assortativity at disease-free endemic...
Abstract Tuberculosis (TB) killed more people globally than any other single pathogen over the past decade. Where surveillance is weak, estimating TB burden estimates uses modeling. In many African countries, increases in HIV prevalence and antiretroviral therapy (ART) have driven dynamic epidemics, complicating estimation of burden, trends, potential intervention impact. We therefore developed a novel age-structured transmission model incorporating evolving demographic HIV/ART effects,...
Abstract Background: Determining the extent of seropositivity SARS-CoV-2 antibody has potential to guide prevention and control efforts. We aimed determine sero prevalence among adults in general population Diredawa, Ethiopia. Method: Community based cross-sectional survey was conducted random sample 648 adult Diredawa from June 15 July 30, 2020 using interview blood collection. Participants were asked about demographic characteristics, COVID-19 symptoms adherence preventive measures....