A5053320934- Immune Response and Inflammation
- Pharmaceutical and Antibiotic Environmental Impacts
- Toxic Organic Pollutants Impact
- Neurological Disorders and Treatments
- X-ray Diffraction in Crystallography
- Spinal Cord Injury Research
- Genomics and Phylogenetic Studies
- Aquatic Ecosystems and Phytoplankton Dynamics
- S100 Proteins and Annexins
- Crystallization and Solubility Studies
- Enzyme Production and Characterization
- Neuroinflammation and Neurodegeneration Mechanisms
- Fatty Acid Research and Health
- Amyotrophic Lateral Sclerosis Research
- Cardiac Ischemia and Reperfusion
- Microbial Community Ecology and Physiology
- Environmental Toxicology and Ecotoxicology
- Nitric Oxide and Endothelin Effects
- Algal biology and biofuel production
University of Insubria
2016
Mario Negri Institute for Pharmacological Research
2011-2012
Bluegreen Strategy (Italy)
2011
Sustained inflammatory reactions are common pathological events associated with neuron loss in neurodegenerative diseases. Reported evidence suggests that Toll-like receptor 4 (TLR4) is a key player of neuroinflammation several However, the mechanisms by which TLR4 mediates neurotoxic signals remain poorly understood. We investigated role vitro and vivosettings motor degeneration. Using primary cultures from mouse spinal cords, we characterized both proinflammatory effects activation...
Cyanobacteria are an interesting group of photosynthetic prokaryotes with a great potential in drug discovery and scientific research. Due to their high degree diversification, they have been able adapt almost all ecological niches. Similarly Gram-negative bacteria, cyanobacterial cell wall contains Lipopolysaccharides (LPSs) the outer membrane layer. LPSs molecules that possess ability elicit innate immune response via Toll-like receptor 4 (TLR-4) activation. Cyanobacterial studied minor...
Abstract Pseudoalteromonas haloplanktis TAB 23 is a Gram‐negative psychrophilic bacterium isolated from the Antarctic coastal sea. To survive in these conditions bacteria have evolved typical membrane lipids and “antifreeze” proteins to protect inner side of microorganism. As for bacteria, outer mainly constituted by lipopoly‐ or lipooligosaccharides (LPS LOS, respectively), which lean towards external environment. Despite this, very little known about peculiarity LPS what their role...