Craig A. Downs

ORCID: 0000-0001-9599-6602
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About
Contact & Profiles
Research Areas
  • Coral and Marine Ecosystems Studies
  • Environmental Toxicology and Ecotoxicology
  • Heat shock proteins research
  • Aquaculture disease management and microbiota
  • Skin Protection and Aging
  • Microplastics and Plastic Pollution
  • Marine and coastal plant biology
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Marine Sponges and Natural Products
  • Ocean Acidification Effects and Responses
  • Photosynthetic Processes and Mechanisms
  • thermodynamics and calorimetric analyses
  • Marine Bivalve and Aquaculture Studies
  • Effects and risks of endocrine disrupting chemicals
  • Physiological and biochemical adaptations
  • Mitochondrial Function and Pathology
  • Insect and Pesticide Research
  • Toxic Organic Pollutants Impact
  • Marine Biology and Environmental Chemistry
  • Coastal and Marine Management
  • Plant Pathogens and Fungal Diseases
  • Algal biology and biofuel production
  • Plant and animal studies
  • Insect and Arachnid Ecology and Behavior
  • Plant Stress Responses and Tolerance

Sorbonne Université
2021-2024

Centre National de la Recherche Scientifique
2021-2024

Sandia National Laboratories California
2024

Laboratoire de Biodiversité et Biotechnologies Microbiennes
2021-2024

National White Collar Crime Center
2006-2023

University of Missouri Health System
2016

University of Hawaiʻi at Mānoa
2009-2013

University of Hawaii System
2009-2013

Pacific Biosciences (United States)
2009-2013

Virginia BioTechnology Research Park
2006

Abstract Evidence suggests that the small chloroplast heat-shock protein (Hsp) is involved in plant thermotolerance but its site of action unknown. Functional disruption this Hsp using anti-Hsp antibodies or addition purified to chloroplasts indicated (a) protects thermolabile photosystem II and, consequently, whole-chain electron transport during heat stress; and (b) completely accounted for acclimation pre-heat-stressed plants. Therefore, a major adaptation acute stress

10.1104/pp.116.1.439 article EN PLANT PHYSIOLOGY 1998-01-01

Coral bleaching is a significant contributor to the worldwide degradation of coral reefs and indicative termination symbiosis between host its symbiotic algae (dinoflagellate; Symbiodinium sp. complex), usually by expulsion or xenophagy (symbiophagy) dinoflagellates. Herein, we provide evidence that during earliest stages environmentally induced bleaching, heat stress light generate distinctly different pathomorphological changes in chloroplasts, while combined heat- light-stress exposure...

10.1371/journal.pone.0077173 article EN cc-by PLoS ONE 2013-12-04

Benzophenone is a mutagen, carcinogen, and endocrine disruptor. Its presence in food products or packaging banned the United States. Under California Proposition 65, there no safe harbor for benzophenone any personal care products, including sunscreens, anti-aging creams, moisturizers. The purpose of this study was to determine (1) if present wide variety commercial sun protection factor (SPF)/sunscreen (2) whether concentration product increased over time, (3) degradation octocrylene likely...

10.1021/acs.chemrestox.0c00461 article EN Chemical Research in Toxicology 2021-03-07

Functional inactivation of the mitochondrial small heat‐shock protein (lmw Hsp) in submitochondrial vesicles using protein‐specific antibodies indicated that this protects NADH:ubiquinone oxidoreductase (complex I), and consequently electron transport from complex I to cytochrome c :O 2 IV). Lmw Hsp function completely accounted for heat acclimation pre‐heat‐stressed plants. Addition purified lmw lacking increased rates 100% assayed at high temperatures. These results indicate production is...

10.1016/s0014-5793(98)00669-3 article EN FEBS Letters 1998-07-03

AbstractCoral bleaching is a major contributor to the global declines of coral reefs. This phenomenon characterized by loss symbiotic algae, their pigments or both. Despite wide scientific interest, mechanisms which occurs still poorly understood. Here we report that removal symbiont during light and temperature stress achieved using host's cellular autophagic-associated machinery. Host sub-cellular morphologies showed increased vacuolization appearance autophagic membranes surrounding...

10.4161/auto.5.2.7405 article EN Autophagy 2009-02-16

Abstract The ocean crisis is urgent and central to human wellbeing life on Earth; past current activities are damaging the planet's main support system for future generations. We witnessing an increase in heat, disturbance, acidification, bio‐invasions nutrients, reducing oxygen levels. Several of these act like ratchets: once detrimental or negative changes have occurred, they may lock place not be reversible, especially at gross ecological process scales. Each change represent a loss...

10.1002/aqc.3182 article EN Aquatic Conservation Marine and Freshwater Ecosystems 2019-07-23

Abstract Sunscreen pollution can be a symptom of unsustainable tourism and coastal development, impacting marine aquatic resources. When introduced into freshwater ecosystems, sunscreen cause cascade insults to the ecological structure, from primary production reducing wildlife reproductive viability fecundity. Without intervention, its associated development in these areas may become self‐destructive, ultimately degrading or destroying natural resources that are principal attractions. The...

10.1002/aqc.3791 article EN cc-by Aquatic Conservation Marine and Freshwater Ecosystems 2022-03-01

Global warming has caused the degradation of coral reefs around world. While stress-tolerant corals have demonstrated ability to acclimatize ocean warming, it remains unclear whether they can sustain their thermal resilience when superimposed with other coastal environmental stressors. We report combined impacts a photosystem II (PSII) herbicide, prometryn, and on Galaxea fascicularis through physiological omics analyses. The results demonstrate that heat-stress-induced inhibition...

10.1021/acs.est.3c10417 article EN Environmental Science & Technology 2024-02-22
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