K. Muhunthan

ORCID: 0000-0001-9615-3033
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About
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Research Areas
  • Reproductive Health and Technologies
  • Blood transfusion and management
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Reproductive Biology and Fertility
  • Ovarian function and disorders
  • Patient Dignity and Privacy
  • Menopause: Health Impacts and Treatments
  • Renal function and acid-base balance
  • Patient-Provider Communication in Healthcare
  • Intimate Partner and Family Violence
  • Blood Coagulation and Thrombosis Mechanisms
  • Acute Myocardial Infarction Research
  • Global Maternal and Child Health
  • Venous Thromboembolism Diagnosis and Management
  • Gestational Trophoblastic Disease Studies
  • Blood donation and transfusion practices
  • Pregnancy and preeclampsia studies
  • Pancreatitis Pathology and Treatment
  • Congenital Diaphragmatic Hernia Studies
  • Pregnancy-related medical research
  • Assisted Reproductive Technology and Twin Pregnancy
  • Liver Disease Diagnosis and Treatment
  • Ethics in Clinical Research
  • Maternal and Perinatal Health Interventions
  • Phytoestrogen effects and research

University of Jaffna
2014-2024

Jaffna Teaching Hospital
2018-2024

St George's, University of London
2016

The use of lengthy, detailed, and complex informed consent forms (ICFs) is paramount concern in biomedical research as it may not truly promote the rights interests participants. extent information ICFs has been subject debates for decades; however, no clear guidance given. Thus, objective this study was to determine perspectives participants about type they need when are invited participate research.This multi-center, cross-sectional, descriptive survey conducted at 54 sites seven...

10.1186/s12910-018-0318-x article EN cc-by BMC Medical Ethics 2018-09-15

To evaluate the pharmacokinetics of tranexamic acid after oral administration to postpartum women.We conducted a single-center pharmacokinetic study at Teaching Hospital-Jaffna, Sri Lanka, on 12 healthy women who delivered vaginally. After 2 g immediate-release 1 hour delivery, parameters were measured plasma samples 0, 0.5, 1, 1.5, 2, 2.5, 3, 3.5, 4, 5, 6, 8, 10, and hours. Plasma concentrations determined by high-performance liquid chromatography. The outcome measures maximum observed...

10.1097/aog.0000000000003750 article EN Obstetrics and Gynecology 2020-03-13

Pregnancy creates significant alterations in energy metabolism which itself is a physiological adaptation to provide continuous flow of metabolites the foetus. The state insulin resistance created by hormonal changes pregnancy enables free glucose foetus and allows its absorption through facilitated diffusion. As preferentially available for foetus, maternal fasting level would be less than that non-pregnant contrast plasma ketones fatty acids levels are elevated, resulting accelerated...

10.1177/2050313x17700743 article EN cc-by-nc SAGE Open Medical Case Reports 2017-01-01

AFLP, though rare, is an obstetric emergency which carries a high incidence of maternal and perinatal mortality, despite optimal care. We report case 23-year-old primi mother, who presented to us with vague symptoms feeling unwell abdominal pain, was diagnosed managed accordingly the highest level care available but succumbed few days into her illness timely delivery able save baby. By this we once again wish emphasize value diagnosis clinical suspicion supportive laboratory investigations...

10.18203/2320-1770.ijrcog20181950 article EN International Journal of Reproduction Contraception Obstetrics and Gynecology 2018-04-28

Objective: To assess the attitude and willingness of medical students Faculty Medicine, University Jaffna, regarding gamete donation. Methods: An institutional-based descriptive cross-sectional study was conducted at from September 2022 to May 2023 among undergraduate who gave their voluntary participation. A self-administered questionnaire used as a instrument collect data toward Results: total 345 participants were recruited socio-demographic revealed that 56.8% female, 62.3% aged between...

10.4103/apjr.apjr_142_23 article EN cc-by-nc-sa Asian Pacific Journal of Reproduction 2024-05-01

Background: Subfertility is a global issue that affects approximately 48 million couples worldwide. Recent advances in fertility care have brought revolutionary reproductive medicine. Assisted Reproductive Technology (ART) one of the upcoming treatment modalities Sri Lanka. Poor knowledge and negative attitudes regarding ART among subfertile will negatively impact their outcome. Objectives: This study assessed attitude towards assisted technology women followed up at Teaching Hospital...

10.4038/bmj.v18i1.30 article EN Batticaloa Medical Journal. 2024-09-25

A BSTRACT Introduction: The Menopause Rating Scale (MRS) is a widely used tool to assess the health-related quality of life (HRQOL) and severity menopausal symptoms in postmenopausal women. objective present study was validate Tamil translation MRS, as not available. Methods: MRS developed following standard methodology, validation psychometric properties done at community level Mannar, Sri Lanka. Reliability assessed through internal consistency test–rest reliability. Validity using...

10.4103/jmh.jmh_174_24 article EN cc-by-nc-sa Journal of Mid-life Health 2024-10-01

Intrauterine insemination is a simple, non-invasive and safe initial treatment option, especially in low resource settings for selected group of patients before initiating assisted reproduction technology treatment. A wise selection timing are key to its success. Detailed assessment the infertile couple, controlled ovarian stimulation with follicular development monitoring, appropriate processing seminal fluid, trigger hCG at correct time, single IUI strict aseptic condition followed by...

10.4038/sljog.v43i4.8002 article EN Sri Lanka Journal of Obstetrics and Gynaecology 2021-12-30

DOI: http://dx.doi.org/10.3126/njog.v9i1.11177 NJOG 2014 Jan-Jun; 2(1):5-7

10.3126/njog.v9i1.11177 article ID cc-by-nc Nepal Journal of Obstetrics and Gynaecology 2014-09-28

Gender-based violence (GBV) is a serious health and social problem in South Asian countries, including Sri Lanka. This study describes the socio-demographic characteristics of clients their alleged perpetrators, types outcomes reported, services provided by GBV Help Desk at Teaching Hospital - Jaffna.Data were collected retrospectively from records all 883 who sought help referred to Jaffna during 2-year period (January 1, 2019 December 31, 2020) using data extraction sheet.The mostly female...

10.4038/jmj.v35i2.192 article EN Jaffna Medical Journal 2023-12-31

Risk estimation and prophylactic treatment of maternal morbidity mortality due to thromboembolism through a standard formal VTE risk assessment tool with numerical scoring is more effective in clinical decision making management than not using system. This study was designed assess the factors prospectively measure uptake pharmacological prophylaxis for postpartum before after introducing tool. MethodsThe conducted 200 women aged 18–39 without randomization. They were followed introduction...

10.4038/jmj.v32i1.89 article EN Jaffna Medical Journal 2020-08-14

Cesarean scar pregnancy is a rare form of ectopic where the conceptus implanted at site previous cesarean section which pauses life-threatening complications if not diagnosed and managed timely. Though numerous types treatment approaches have been described there no consensus on optimal modality challenge to clinicians. Current are combination medical surgical interventions with varying success rates complications.

10.23937/2377-9004/1410211 article EN Obstetrics and Gynaecology Cases - Reviews 2021-10-22

Invasive mole (IM) is one of the Gestational trophoblastic neoplasia lesions, characterized by local invasion with rare distal spread. It could follow any type pregnancy and commonly arising from a complete hydatidiform (CHM). Pathogenesis due to an underlying oocyte defect. Embryos are examined for triploidy exclude dispermic fertilization in assisted reproduction technology (ART). Besides, several potential mechanisms risk factors had been described explain gestational (GTN) following ART.

10.23937/2377-9004/1410210 article EN Obstetrics and Gynaecology Cases - Reviews 2021-10-22
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