Suman Kanungo
A5019766599- Vibrio bacteria research studies
- Child Nutrition and Water Access
- Viral gastroenteritis research and epidemiology
- COVID-19 epidemiological studies
- Vaccine Coverage and Hesitancy
- Influenza Virus Research Studies
- Salmonella and Campylobacter epidemiology
- Escherichia coli research studies
- Global Maternal and Child Health
- Viral Infections and Immunology Research
- Food Security and Health in Diverse Populations
- Healthcare Systems and Reforms
- Gut microbiota and health
- Mosquito-borne diseases and control
- Fecal contamination and water quality
- Animal Virus Infections Studies
- Global Public Health Policies and Epidemiology
- Antibiotic Resistance in Bacteria
- Clostridium difficile and Clostridium perfringens research
- Antibiotic Use and Resistance
- Viral Infections and Vectors
- Pneumonia and Respiratory Infections
- Hepatitis Viruses Studies and Epidemiology
- Respiratory viral infections research
- Probiotics and Fermented Foods
National Institute of Cholera and Enteric Diseases
2016-2025
Indian Council of Medical Research
2012-2025
German Center for Neurodegenerative Diseases
2025
University of Bonn
2025
Creative Commons
2023
University of Exeter
2023
Background The importance of Cryptosporidium as a pediatric enteropathogen in developing countries is recognized. Methods Data from the Global Enteric Multicenter Study (GEMS), 3-year, 7-site, case-control study moderate-to-severe diarrhea (MSD) and GEMS-1A (1-year MSD less-severe [LSD]) were analyzed. Stools 12,110 3,174 LSD cases among children aged <60 months 21,527 randomly-selected controls matched by age, sex community immunoassay-tested for Cryptosporidium. Species subset...
Diarrheal diseases remain a leading cause of illness and death among children younger than 5 years in low-income middle-income countries. The Global Enteric Multicenter Study (GEMS) has described the incidence, aetiology, sequelae medically attended moderate-to-severe diarrhoea (MSD) aged 0-59 months residing censused populations sub-Saharan Africa south Asia, where most child deaths occur. To further characterise this disease burden guide interventions, we extended study to include with...
The Global Enteric Multicenter Study (GEMS) was a 3-year case-control study that measured the burden, aetiology, and consequences of moderate-to-severe diarrhoea (MSD) in children aged 0-59 months. GEMS-1A, 12-month follow-on study, comprised two parallel studies, one assessing MSD other less-severe (LSD). In this report, we analyse risk death with each type specific pathogens associated fatal outcomes.GEMS prospective, age-stratified, matched done at seven sites Africa Asia. Children months...
Typhoid fever remains an important cause of illness and death in the developing world. Uncertainties about protective effect Vi polysaccharide vaccine children under age 5 years vaccine's programmatic conditions have inhibited its use countries.
Background Killed oral cholera vaccines (OCVs) have been licensed for use in developing countries, but protection conferred by OCVs beyond two years of follow-up has not demonstrated randomized, clinical trials. Methods/Principal Findings We conducted a cluster-randomized, placebo-controlled trial two-dose regimen low-cost killed whole cell OCV residents 1 year age and older living 3,933 clusters Kolkata, India. The primary endpoint was culture-proven Vibrio cholerae O1 diarrhea episodes...
Abstract Background Malnutrition, a major health problem, affects significant proportion of preschool children in developing countries. The devastating consequences malnutrition include diarrhoea, malabsorption, increased intestinal permeability, suboptimal immune response, etc. Nutritional interventions and dietary solutions have not been effective for treatment till date. Metagenomic procedures allow one to access the complex cross-talk between gut its microbial flora understand how...
Rotavirus is the most common cause of moderate-to-severe infant diarrhoea in developing countries, resulting enormous morbidity, mortality, and economic burden. A bovine-human reassortant pentavalent rotavirus vaccine (BRV-PV) targeting globally strains was developed India tested a randomized, double-blind, placebo-controlled end-point driven Phase III efficacy clinical trial implemented at six sites across India. Infants 6 to 8 weeks age were randomized (1:1) receive three oral doses BRV-PV...
Background Enterotoxigenic Escherichia coli (ETEC) encoding heat-stable enterotoxin (ST) alone or with heat-labile (LT) cause moderate-to-severe diarrhea (MSD) in developing country children. The Global Enteric Multicenter Study (GEMS) identified ETEC ST among the top four enteropathogens. Since GEMS objective was to provide evidence guide development and implementation of enteric vaccines other interventions diminish diarrheal disease morbidity mortality, we examined colonization factor...
ABSTRACT Background We report the clinical efficacy against COVID-19 infection of BBV152, a whole-virion inactivated SARS-CoV-2 vaccine formulated with Toll-like receptor 7/8 agonist molecule adsorbed to alum (Algel-IMDG). Methods did double-blind, randomised, multicentre, phase 3 trial in 25 Indian hospitals evaluate efficacy, safety, and immunological lot consistency BBV152. Healthy adults (age 18–98 years) randomised 1:1 using computer-generated randomisation scheme received two...
The association between childhood diarrheal disease and linear growth faltering in developing countries is well described. However, the impact attributed to specific pathogens has not been elucidated, nor of recommended antibiotic treatment.The Global Enteric Multicenter Study enrolled children with moderate severe diarrhea (MSD) seeking healthcare at 7 sites sub-Saharan Africa South Asia. At enrollment, we collected stool samples identify enteropathogens. Length/height was measured...
In 2017, more than half the cases of typhoid fever worldwide were projected to have occurred in India. absence contemporary population-based data, it is unclear whether declining trends hospitalization for India reflect increased antibiotic treatment or a true reduction infection.
To more accurately define the annual incidence of cholera in India, believed to be higher than reported World Health Organization (WHO).
An effective vaccine against cholera has been used for public health purposes in Vietnam since the 1990s. This was reformulated to meet WHO requirements. We assessed safety and immunogenicity of bivalent (Vibrio cholerae 01 0139) killed whole cell oral a endemic area Kolkata, India.Double-blind, randomized, placebo controlled trial.The trial conducted clinical ward Infectious Diseases Hospital India.The participants were 101 healthy adults (males non-pregnant females) aged 18-40 years 100...
Background. We evaluated the herd protection conferred by an oral cholera vaccine using 2 approaches: cluster design and geographic information system (GIS) design.
Conducting population-based serosurveillance for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) will estimate and monitor the trend of infection in adult general population, determine socio-demographic risk factors delineate geographical spread infection. For this purpose, a serial cross-sectional survey would be conducted with sample size 24,000 distributed equally across four strata districts categorized on basis incidence reported cases COVID-19. Sixty included survey....
Recent research has indicated that the malaria burden in Asia may have been vastly underestimated. We conducted a prospective community-based study an impoverished urban site Kolkata, India, to estimate of and typhoid fever identify risk factors for these diseases. In population 60452 people, 3605 episodes were detected over 12-month period. The blood films 93 febrile patients contained Plasmodium (90 P. vivax, 2 falciparum 1 malariae). Blood cultures from 95 grew Salmonella enterica...
<b>Aims:</b> To conduct a prospective, community based study in an impoverished urban site Kolkata (formerly Calcutta) order to measure the burden of cholera, describe its epidemiology, and search for potential risk factors that could be addressed by public health strategies. <b>Methods:</b> The population was enumerated at beginning end period. Surveillance through five field outposts two referral hospitals acute, watery, non-bloody diarrhoea conducted from 1 May 2003 30 April 2004. Data...