C. P. Girish Kumar
A5043496374- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Viral gastroenteritis research and epidemiology
- Antifungal resistance and susceptibility
- COVID-19 epidemiological studies
- Pneumonia and Respiratory Infections
- Fungal Infections and Studies
- Animal Virus Infections Studies
- Respiratory viral infections research
- Mosquito-borne diseases and control
- Long-Term Effects of COVID-19
- Vaccine Coverage and Hesitancy
- Hepatitis Viruses Studies and Epidemiology
- Viral Infections and Immunology Research
- Bacterial Infections and Vaccines
- Pneumocystis jirovecii pneumonia detection and treatment
- SARS-CoV-2 detection and testing
- Viral Infections and Vectors
- Plant Genetic and Mutation Studies
- Genetic and Environmental Crop Studies
- Congenital Anomalies and Fetal Surgery
- Hepatitis B Virus Studies
- HIV/AIDS Research and Interventions
- Hepatitis C virus research
- Antibiotic Use and Resistance
Indian Council of Medical Research
2016-2024
National Institute of Epidemiology
2013-2024
CPCL Polytechnic College
2021
National Institute of Research in Tuberculosis
2021
Regional Medical Research Centre
2019
ICMR-National Institute of Virology
2017-2019
Directorate of Health
2019
Government Medical College
2019
Central Coastal Agricultural Research Institute
2019
Dr. Rajendra Prasad Government Medical College
2015-2019
Background & objectives: Population-based seroepidemiological studies measure the extent of SARS-CoV-2 infection in a country. We report findings first round national serosurvey, conducted to estimate seroprevalence among adult population India. Methods: From May 11 June 4, 2020, randomly sampled, community-based survey was 700 villages/wards, selected from 70 districts 21 States India, categorized into four strata based on incidence reported COVID-19 cases. Four hundred adults per...
BackgroundThe first national severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serosurvey in India, done May–June, 2020, among adults aged 18 years or older from 21 states, found a SARS-CoV-2 IgG antibody seroprevalence of 0·73% (95% CI 0·34–1·13). We aimed to assess the more recent nationwide general population India.MethodsWe did second household individuals 10 same 700 villages wards within 70 districts India that were included serosurvey. Individuals younger than and...
BackgroundEarlier serosurveys in India revealed seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) 0.73% May–June 2020 and 7.1% August–September 2020. A third serosurvey was conducted between December January 2021 to estimate the SARS-CoV-2 infection among general population healthcare workers (HCWs) India.MethodsThe same 70 districts as first second serosurveys. For each district, at least 400 individuals aged ≥10 years from 100 HCWs subdistrict-level health...
Background India began COVID-19 vaccination in January 2021, initially targeting healthcare and frontline workers. The strategy was expanded a phased manner currently covers all individuals aged 18 years above. experienced severe second wave of during March–June 2021. We conducted fourth nationwide serosurvey to estimate prevalence SARS-CoV-2 antibodies the general population ≥6 workers (HCWs). Methods findings did cross-sectional study between 14 June 6 July 2021 same 70 districts across 20...
Abstract Monocytes are thought to play an important role in host defence and pathogenesis of COVID-19. However, a comprehensive examination monocyte numbers function has not been performed longitudinally acute convalescent We examined the absolute counts monocytes, frequency subsets, plasma levels activation markers using flowcytometry ELISA seven groups COVID-19 individuals, classified based on days since RT-PCR confirmation SARS-CoV2 infection. Our data shows that total monocytes...
Conducting population-based serosurveillance for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) will estimate and monitor the trend of infection in adult general population, determine socio-demographic risk factors delineate geographical spread infection. For this purpose, a serial cross-sectional survey would be conducted with sample size 24,000 distributed equally across four strata districts categorized on basis incidence reported cases COVID-19. Sixty included survey....
Outbreaks of acute encephalitis syndrome (AES) have been occurring in Gorakhpur Division, Uttar Pradesh, India, for several years. In 2016, we conducted a case-control study. Our findings revealed high proportion AES cases with Orientia tsutsugamushi IgM and IgG, indicating that scrub typhus is cause AES.
In 2016, the Government of India introduced oral rotavirus vaccine (ROTAVAC, Bharat Biotech, India) in 4 states as part Universal Immunization Programme, and expanded to 5 more 2017. We report four years data on gastroenteritis hospitalized children < age prior introduction.Children from 7 sites southern northern for diarrhoea were recruited between July 2012 June 2016. Stool samples screened using enzyme immunoassay (EIA). The EIA positive genotyped by reverse-transcription polymerase chain...
Background Worldwide, acute bacterial meningitis is a major cause of high morbidity and mortality among under five children, particularly in settings where vaccination for H. influenzae type b, S. pneumoniae N. meningitidis yet to be introduced the national immunization programs. Estimation disease burden associated with these pathogens can guide policy makers consider inclusion newer vaccines A network hospital based sentinel surveillance was established generate baseline data on children...
A three-dose, oral rotavirus vaccine (Rotavac) was introduced in the universal immunization program India 2016. prelicensure trial involving 6799 infants not large enough to detect a small increased risk of intussusception. Postmarketing surveillance data would be useful assessing whether intussusception similar seen with different vaccines used other countries.
Since its re-emergence in 2005, chikungunya virus (CHIKV) transmission has been documented most Indian states. Information is scarce regarding the seroprevalence of CHIKV India. We aimed to estimate age-specific seroprevalence, force infection (FOI), and proportion population susceptible infection.We did a nationally representative, cross-sectional serosurvey, which we randomly selected individuals three age groups (5-8, 9-17, 18-45 years), covering 240 clusters from 60 districts 15 states...
Abstract We conducted a cross-sectional survey to estimate the seroprevalence of IgG against severe acute respiratory syndrome coronavirus 2 in Chennai, India. Among 12,405 serum samples tested, weighted was 18.4% (95% CI 14.8%–22.6%). These findings indicate most population Chennai is still susceptible this virus.
In April 2016, an indigenous monovalent rotavirus vaccine (Rotavac) was introduced to the National Immunization Program in India. Hospital-based surveillance for acute gastroenteritis conducted five sentinel sites from 2012 2020 monitor impact on various genotypes and reduction positivity at each site. Stool samples collected children under 5 years of age hospitalized with diarrhea were tested group A using a commercial enzyme immunoassay, strains characterized by RT-PCR. The proportion...
Abstract T cells are thought to be an important correlates of protection against SARS-CoV2 infection. However, the composition cell subsets in convalescent individuals infection has not been well studied. The authors determined lymphocyte absolute counts, frequency memory subsets, and plasma levels common γ−chain 7 groups COVID-19 individuals, based on days since RT-PCR confirmation SARS-CoV-2 data show that both counts frequencies lymphocytes as as, CD4+ central effector increased, naïve...
In the ongoing COVID-19 pandemic, an increased incidence of ROCM was noted in India among those infected with COVID. We determined risk factors for rhino-orbito-cerebral mucormycosis (ROCM) post Coronavirus disease 2019 (COVID-19) never and ever hospitalized separately through a multicentric, hospital-based, unmatched case-control study across India.We defined cases controls as without post-COVID ROCM, respectively. compared their socio-demographics, co-morbidities, steroid use, glycaemic...
Avahan, the India AIDS Initiative, a large-scale HIV prevention program, using peer-mediated approaches and STI services, was implemented for high-risk groups in six states India. This paper describes assessment of program among female sex workers (FSWs) southern state Tamil Nadu. An analytical framework based on Avahan impact evaluation design used. Routine monitoring data, two rounds cross-sectional biological behavioural surveys FSWs 2006 (Round 1) 2009 2) quality assessments clinical...
This paper presents an evaluation of Avahan, a large scale HIV prevention program that was implemented using peer-mediated strategies, condom distribution and sexually transmitted infection (STI) clinical services among high-risk men who have sex with (HR-MSM) male to female transgender persons (TGs) in six high-prevalence state Tamil Nadu, southern India. Two rounds cross-sectional bio-behavioural surveys HR-MSM TGs routine monitoring data were used assess changes coverage, use prevalence...
Abstract We conducted a serosurvey of 155 healthcare workers and 124 household community members who had close contact with 18 patients laboratory-confirmed Nipah virus infections in Kerala, India. detected 3 subclinical infections; 2 persons IgM IgG 1 only against virus.
Abstract After the introduction of rotavirus vaccine into Universal Immunization Program in India 2016, relatively few studies have assessed prevalence and epidemiological patterns acute gastroenteritis (AGE) among hospitalized children ≤5 years age. We used a uniform protocol to recruit with AGE as well standardized testing typing protocols. Stool specimens from younger than 5 age admitted six hospitals three cities were collected January 2017 through December 2019. Norovirus was detected...