A5020250905- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Child Nutrition and Water Access
- Hepatitis Viruses Studies and Epidemiology
- Animal Virus Infections Studies
- Artificial Intelligence in Healthcare
- Escherichia coli research studies
- Parasitic Infections and Diagnostics
- Parasites and Host Interactions
- Eosinophilic Esophagitis
- Data-Driven Disease Surveillance
- Blockchain Technology Applications and Security
- Immune Response and Inflammation
- COVID-19 epidemiological studies
- Inflammatory Bowel Disease
- COVID-19 diagnosis using AI
- Artificial Intelligence in Healthcare and Education
- Immune Cell Function and Interaction
- Autoimmune and Inflammatory Disorders Research
- Congenital Anomalies and Fetal Surgery
- Zoonotic diseases and public health
- Gastrointestinal motility and disorders
Christian Medical College & Hospital
2021-2025
Christian Medical College
2024
In April 2016, an indigenous monovalent rotavirus vaccine (Rotavac) was introduced to the National Immunization Program in India. Hospital-based surveillance for acute gastroenteritis conducted five sentinel sites from 2012 2020 monitor impact on various genotypes and reduction positivity at each site. Stool samples collected children under 5 years of age hospitalized with diarrhea were tested group A using a commercial enzyme immunoassay, strains characterized by RT-PCR. The proportion...
Soil-transmitted helminths (STH) are one of the most prevalent enteric infections world-wide. To control STH-related morbidity, World Health Organization recommends targeted deworming and improvements in water, sanitation hygiene. Current surveillance strategies for STH focus on identifying quantifying eggs stool samples via microscopy, which exhibits poor specificity sensitivity, especially settings with low-intensity infections. Wastewater-based epidemiology is a tool used to monitor...
Abstract After the introduction of rotavirus vaccine into Universal Immunization Program in India 2016, relatively few studies have assessed prevalence and epidemiological patterns acute gastroenteritis (AGE) among hospitalized children ≤5 years age. We used a uniform protocol to recruit with AGE as well standardized testing typing protocols. Stool specimens from younger than 5 age admitted six hospitals three cities were collected January 2017 through December 2019. Norovirus was detected...
Malnourished children are at higher risk of mortality and morbidity following diarrheal illness certain enteropathogens have been associated with malnutrition in children. Very few studies comprehensively looked the etiology diarrhea malnourished most used conventional diagnostic methods suboptimal sensitivity. We a highly sensitive molecular approach against broad range pathogens causing examined their association malnutrition. In addition, we pathogen diversity pediatric diarrhea, three...
Abstract Rotaviruses (RVs) are the most common etiological agent of acute gastroenteritis among young children, even after vaccine introduction in low-income countries. A whole-genome classification representing 11 RV genes, was introduced for surveillance and characterization RVs. This study characterized circulating strains Vellore, India from 2002 to 2017 understand rotavirus strain diversity evolution using Whole genome sequencing (WGS) carried out on Illumina MiSeq. The 89% (92%...
Abstract Sepsis associated Hemophagocytic Lymphohistiocytosis (SHLH) is an underrecognized fatal complication of sepsis which requires early diagnosis and aggressive immunosuppressive treatment. However, overlapping clinical symptoms between SHLH makes the challenging. Few recent studies have indicated utility immune signatures in distinguishing from HLH due to various underlying triggers. In this cross-sectional study, we evaluated proportions T cell subsets, their activation status (%...
Abstract Soil-transmitted helminths (STH) are one of the most prevalent enteric infections world-wide. To control STH-related morbidity, World Health Organization recommends targeted deworming and improvements in water, sanitation hygiene. Current surveillance strategies for STH focus on identifying quantifying eggs stool samples via microscopy, which exhibits poor specificity sensitivity, especially settings with low-intensity infections. Wastewater-based epidemiology is a tool used to...
Comprehensive reviews on the use and utility of point-of-care tests (POCs) in public health programs relation to infectious disease nutrition are limited. Point-of-care technologies have potential improve management diseases particularly settings where healthcare infrastructure timely access quality medical care
Artificial Intelligence (AI) is revolutionizing healthcare, mainly in diagnostics and most cancers treatment, via improving accuracy, performance, personalized care. Advanced gadget learning algorithms examine medical records, such as imaging scans, pathology slides, genetic facts, to come across illnesses at advance stages predict patient outcomes with extraordinary precision. AI-pushed gear radiology aid figuring out tumors, assessing their aggressiveness, suggesting potential remedy...