A5027126148- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Animal Virus Infections Studies
- Hepatitis Viruses Studies and Epidemiology
- Sepsis Diagnosis and Treatment
- Pharmaceutical studies and practices
- Congenital Diaphragmatic Hernia Studies
- Tracheal and airway disorders
- Child Abuse and Related Trauma
- Female Genital Mutilation/Cutting Issues
- Long-Term Effects of COVID-19
- Ultrasound in Clinical Applications
- Polyomavirus and related diseases
- Neonatal Health and Biochemistry
- Nosocomial Infections in ICU
- Epilepsy research and treatment
- Tumors and Oncological Cases
- Histiocytic Disorders and Treatments
- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Vasculitis and related conditions
- Myasthenia Gravis and Thymoma
- Pharmacological Effects and Toxicity Studies
- Pharmaceutical Practices and Patient Outcomes
- Neonatal and Maternal Infections
Bharati Vidyapeeth Deemed University
2009-2024
B. J. Medical College & Sassoon Hospital
2015
ICMR-National Institute of Virology
2014
The study was conducted to investigate the molecular epidemiology of noroviruses (NoVs) from western India. A total 830 fecal specimens were collected during July 2005-June 2007 children, < or =7 years age suffering acute gastroenteritis in Pune, Nagpur, and Aurangabad cities. All subjected RT-PCR, sequencing phylogenetic analysis for detection characterization Genogroup I (GI) GII NoVs. NoV positivity varied between 6.3% 12.6% different cities with predominance (96.6%). infections very...
Acute kidney injury (AKI) is common in patients the pediatric intensive care unit (PICU) and associated with poor outcome. We conducted present study to determine incidence, risk factors outcomes of AKI PICU.We collected data retrospectively from case records children admitted PICU during one year. defined classified according modified pRIFLE criteria. used multivariate logistic regression association mortality morbidity.Of 252 included study, 103 (40.9%) developed AKI. Of these AKI, 39...
A vast diversity in rotaviruses at inter- and intra-genotypic level underscores the need for monitoring of circulating rotavirus strains. The aim this study was to update data on disease strains period from January 2009 December 2012 Pune, western India which has been one sites Indian Rotavirus Strain Surveillance Network since November 2005.Children aged <5 years admitted acute gastroenteritis three different hospitals Pune city were included study. stool specimens collected tested antigen...
Abstract After the introduction of rotavirus vaccine into Universal Immunization Program in India 2016, relatively few studies have assessed prevalence and epidemiological patterns acute gastroenteritis (AGE) among hospitalized children ≤5 years age. We used a uniform protocol to recruit with AGE as well standardized testing typing protocols. Stool specimens from younger than 5 age admitted six hospitals three cities were collected January 2017 through December 2019. Norovirus was detected...
Abstract Recently, rotavirus antigenemia and viremia have been identified in patients with acute gastroenteritis. This study examined children hospitalized for gastroenteritis order to establish its association fecal shedding of rotavirus, infecting genotypes antibody marker infection. Thirty‐one pairs stool–serum specimens were collected from November 2004 February 2005 together clinical information. All paired screened RNA by RT‐PCR using the VP6 gene primers. stool serum tested antigen...
Abstract Background From 2016, the Government of India introduced oral rotavirus vaccine into national immunization schedule. Currently, two indigenously developed vaccines (ROTAVAC, Bharat Biotech; ROTASIIL, Serum Institute India) are included in Indian program. We report disease burden and diversity genotypes from 2005 to 2016 a multi-centric surveillance study before introduction vaccines. Methods A total 29,561 stool samples collected (7 sites during 2005–2009, 3 2009 2012, 28 2012–2016)...
Background: Sepsis can be defined as the body's response to an infection. in children remains a significant cause of morbidity and mortality worldwide. Objectives: This study focuses on etiological factors, risk clinical characteristics sepsis neonate pediatric patients. Patients Methods: A prospective was conducted over six-month period neonatal intensive care units Bharati hospital research centre, Pune. Fifty-two patients aged 0 - 12 years who were diagnosed with included study. Data...
Spontaneous perforation of esophagus in neonates is a rare occurrence. However iatrogenic the not that uncommon, and most frequently seen preterm low birth weight infants. In premature infants, an esophageal (EP) mainly occurs while inserting orogastric tube. The commonly reported symptoms EP are sudden onset respiratory distress, due to pleural effusion pneumothorax. our case neonate presented with apnea requiring ventilation. We present Extremely Low Birth Weight (ELBW) who recurrent...
Functional echocardiography, as opposed to echocardiography performed by the cardiologist, is bedside utilization of cardiac ultrasound take after functional and haemodynamic changes longitudinally. Information reflecting cardiovascular capacity systemic pulmonary blood flow in sick preterm term neonates can be observed utilizing this strategy. lacking on its use neonatal units India.To characterize impact (FnECHO) programme decision making a tertiary care centre India evaluating frequency...
Abstract Four gastroenteritis viruses were responsible for 54% of the acute (AGE) cases in children hospitalized between May 2017 and December 2019 Pune city Maharashtra state, Western India. The majority (79%) <2 years age. prevalence Rotavirus A (RVA) was 30.5% followed by 14.3% norovirus, 8.4% adenovirus, 5.5% astrovirus. severity disease highest patients with coinfections compared a single infection or negative all ( p = 0.024). Genotyping analysis showed that RVA‐positive samples...
We report a case of an extremely low birth weight (ELBW) infant presenting with pulmonary hemorrhage (PH) in which we have given surfactant after acute episode bleeding severe intractable hypoxemia. Surfactant replacement therapy showed improvement Mean Airway Pressure (MAP) and oxygenation indices. Our suggests that is useful PH.
Abstract Objectives To assess the extent of use, patterns, variables and Adverse Drug Reactions associated with off label prescribing in Pediatrics. Methods A prospective observational study was conducted for a period 6 months children age group 0-17 years tertiary care Hospital Maharashtra, India. Off drug use assessed using Micromedex British National Formulary Children (BNFC 2016–2017). (ADRs) were according to physicians' notes, recorded during patient's hospital stay. Pearson...
Parenting a child with special health care needs (SHCN) is often stressful. This study aimed to measure and compare stress among mothers of children (a) Autism Spectrum Disorder (ASD) - ASD group, (b) Developmental delay without (c) SHCN developmental (d) Typically developing group. To assess factors associated maternal in disorders.A cross-sectional analytical was performed aged 2-12 years their mothers. The population classified into four groups as defined above help detailed history, &...
Adequate controlled clinical trials in pediatric population, especially oncology and vaccinations are still insufficient due to ethical considerations. Certain conditions children general Indian particular, suggested the need for Adverse Drug Reaction (ADR) monitoring. Thus this study was aimed investigate incidence of ADRs populations. A prospective spontaneous reporting conducted over a period six months from October 2012 March 2013 inpatients ward Bharati Hospital Pune. Reported were...
We report a 12 yr old boy who presented with recurrent gross hematuria, polyuria and rickets growth failure. Investigations showed bilateral renal calculi small kidneys on ultrasonography along hypercalciuria; hypomagnesemia reduced kidney function. His younger sibling also had nephrocalcinosis hypomagnesemia. The genetic analysis done in view of chronic disease homozygous missense variant (c.392G>A) at exon 4 CLDN 16 gene suggestive Familial hypercalciuria (FHHNC). similar mutation the...
BackgroundNeutralization of virus infectivity has been suggested as the key mechanism immunological defence against rotavirus infection. In India, in addition to Rotarix™ and RotaTeq®, two new vaccines i.e. ROTAVAC®; a monovalent vaccine ROTASIIL®; bovine-human reassortant multivalent are included under National Immunization programme. The aim study was determine comparative analysis neutralizing antibody (NAbs) responses most common RV types (G1–G4, G9 G12) among ROTAVAC® ROTASIIL®...
A BSTRACT Focal cerebral arteriopathies, vasculitis, microangiopathies, coagulopathies, and in-situ microthrombi leading to territorial infarction of neural tissues are some the most recent instances which reported as a consequence infection caused by novel coronavirus (SARS-CoV-2). Acute ischemic stroke (AIS) is one major neurological manifestations that have been linked with COVID-19. We describe case 5-year-old boy who had an acute-onset bilateral arm leg weakness due posterior...
Subacute sclerosing panencephalitis (SSPE) is a recognized neurodegenerative illness, known to be caused by the persistence of mutated measles virus in neurons and oligodendrocytes. The typical SSPE picture involves behavioral issues followed myoclonic jerks, progressive intellectual cognitive decline, bedriddenness, an incontinent (vegetative) state leading death. Considering atypicality, ataxia, tremors, dystonia, hemiparkinsonian features are documented. Very few cases early-onset have...
Thymoma is a rare case presenting in the paediatric age group. Only 30 cases have been reported so far. Our 14 month old female, presented with respiratory distress. CT scan showed gross widening of superior mediastinum homogeneous opacity. Immunohistochemistry was suggestive thymoma. She underwent excision thymic mass and well at present.J Nepal Paediatr Soc 2015;35(1):76-78