A5066108383- Neonatal Respiratory Health Research
- Neonatal and fetal brain pathology
- Ultrasound in Clinical Applications
- Sepsis Diagnosis and Treatment
- COVID-19 Impact on Reproduction
- Vascular Malformations and Hemangiomas
- Congenital Diaphragmatic Hernia Studies
- Breastfeeding Practices and Influences
- Pulmonary Hypertension Research and Treatments
- Nosocomial Infections in ICU
- Neonatal and Maternal Infections
- Vascular Malformations Diagnosis and Treatment
- Central Venous Catheters and Hemodialysis
- Telemedicine and Telehealth Implementation
- Blood properties and coagulation
- Chronic Disease Management Strategies
- Atomic and Subatomic Physics Research
- Congenital Heart Disease Studies
- Kawasaki Disease and Coronary Complications
- Streptococcal Infections and Treatments
- Fetal and Pediatric Neurological Disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Biomedical Research and Pathophysiology
- Infant Nutrition and Health
- Cardiovascular Conditions and Treatments
Bharati Vidyapeeth Deemed University
2013-2025
KIIT University
2021
B. J. Medical College & Sassoon Hospital
2015
Military Hospital
2008
Armed Forces Medical College
2008
Abstract Background The incidence of neonatal septic shock in low-income countries is 26.8% with a mortality rate 35.4%. evidence the hemodynamic effects noradrenaline neonates remains sparse. This study was carried out to evaluate shock. Methods single-center prospective cohort tertiary care hospital’s level III intensive unit. Neonates and those who received as first-line vasoactive agent were included. Clinical parameters recorded before after one hour infusion. primary outcomes were:...
Arteriovenous malformations (AVMs) are rare congenital vascular with associated morbidities. We describe a neonatal case of upper limb high-flow AVM presenting soft tissue mass and postnatal high-output heart failure. Doppler study suggested AVM, later magnetic resonance angiography the right confirmed diagnosis. The baby was managed respiratory support, compression bandage elevation, oral sirolimus percutaneous embolisation. After embolisation using glue, there reduction in size swelling...
To establish normal ranges for the lateral, third, and fourth ventricular dimensions ventriculo-hemispheric ratio (VHR) in neonates using cranial ultrasonography.Intra-cranial ventricles were assessed ultrasonographically anterior fontanelle as acoustic window. Data analyzed to determine correlation, coefficient of determination (R2), regression equations plotted against gestational age (GA).Of total 1483 (25-42 w GA), 372(25%) had GA < 34 weeks. strongly correlated with horn width (AHW;...
Sildenafil is the drug of choice for neonatal pulmonary hypertension in developing countries where inhaled nitric oxide not available. Available as oral and intravenous preparation - no study has been done past to compare two forms. Each its own benefits but requires comparison terms efficacy safety. This was versus (IV) sildenafil infants with mild moderate hypertension.
Lung ultrasound is an accurate and early predictor for surfactant replacement therapy in respiratory distress syndrome (RDS) as compared to clinical parameters chest x-ray. However, lung pathologies at birth have overlapping symptomatology low middle-income countries a higher incidence of congenital pneumonia, addition RDS, making the immediate diagnosis difficult. Thus, there need assessing cutoff scores given setting.The primary objective was determine diagnostic accuracy score (LUS)...
Background: Propranolol has emerged as front-line therapy for infantile hemangiomas (IHs). However, a well-defined protocol administering and predicting response to propranolol is unavailable. Methods: In this open-label trial, 31 children with IH (median age=5 mo; range,1 mo 9 y) were administered (2 mg/kg/d) median duration of 28 weeks (12 50 wk). They compared 14 historical controls who did not receive any treatment. An image-based scoring system was used assess involution. Results:...
Functional echocardiography, as opposed to echocardiography performed by the cardiologist, is bedside utilization of cardiac ultrasound take after functional and haemodynamic changes longitudinally. Information reflecting cardiovascular capacity systemic pulmonary blood flow in sick preterm term neonates can be observed utilizing this strategy. lacking on its use neonatal units India.To characterize impact (FnECHO) programme decision making a tertiary care centre India evaluating frequency...
Inadequate quality of care has been identified as one the most significant challenges to achieving universal health coverage in low-income and middle-income countries. To address this WHO-SEARO, point improvement (POCQI) method developed. This paper describes developing a dynamic framework for implementation POCQI across India from 2015 2020.
Feed intolerance and necrotising enterocolitis (NEC) are challenges while treating sick neonates. These can be reduced by giving human milk, but adequate availability of mother’s own milk or pasteurised donor (PDHM) is a challenge in neonatal setups, like ours, without an attached bank. Hence, this quality improvement initiative was taken to improve collection our urban tertiary-care teaching hospital, at least 500 mL per week 4 weeks. After analysing the problem, team identified shortage...
We describe a case of premature infant with antenatally detected retroperitoneal arteriovenous malformation (AVM) extensive intraspinal extension. Treatment the embolectomy and sclerotherapy was not feasible in view extensions small size vessels lesion. During trial propranolol over 20 days, lesion progressed size, roughly doubling volume accompanied deranged coagulation parameters. therefore switched to oral prednisolone sirolimus. The steroid stopped after 6 weeks sirolimus continued serum...
Background: Clinical, pathologic, and genetic heterogeneity is a challenge in identifying classifying congenital dyserythropoietic anemia (CDA). CDA type IV, the rarest with only 11 reported cases, results from KLF1 gene mutation. Clinical Description: A male preterm neonate presented jaundice, anemia, pulmonary hypertension hepatosplenomegaly immediate postnatal period, requiring multiple red blood cell transfusions. Management Outcome: The workup for non-immune haemolytic including...
Transcutaneous bilirubin (TcB) measurements during and after phototherapy for hyperbilirubinemia must be performed on unexposed skin. There are commercially made skin patches this purpose, but they relatively unavailable in low-resource settings. We devised a simple cotton patch tested its use TcB phototherapy.
Limited data exists on noradrenaline therapy in neonatal septic shock. We compared the efficacy of with adrenaline This single center, open label, pilot randomized controlled trial included neonates clinical evidence sepsis and
Nosocomial infections are among the leading causes of mortality and morbidity in neonatal intensive care units. The incidence outcome these determined by degree immaturity immune system, invasive procedures involved, aetiological agent its antimicrobial susceptibility pattern and, above all, infection control policies practiced unit. interventions to prevent health associated based on strategies that interrupt transmission organism newborn (hand ‘degerming’, optimal spacing staffing,...
Background Neonatal sepsis is a leading cause of morbidity and mortality among admitted neonates. Healthcare-associated infection (HAI) significant contributor in this cohort. Local problem In our unit, 16.1% the admissions developed during their stay unit. Method We formed team all stakeholders to address issue. The was analysed using various tools, main contributing factor low compliance with hand hygiene handling intravenous lines. Interventions scrub hub/aseptic non-touch technique/five...
Most reports of COVID-19 in neonates suggest that they are infected postnatally and present with gastrointestinal or respiratory symptoms. We describe a neonate who had community-acquired COVID-19, presented late-onset sepsis developed dyselectrolytemia. The 26-day-old male baby fever, feed refusal shock. Rapid antigen test for SARS-CoV-2 by nasopharyngeal swab was positive levels circulating inflammatory markers were high. supported antibiotics, inotropic vasopressor drugs. He seizures...
Congenital hyperinsulinism (CHI) characterised by inappropriate secretion of insulin despite low blood glucose can result in irreversible brain damage if not promptly treated. The most common genetic cause is the pathogenic variants ABCC8 and KCNJ11 , causing dysregulated secretion. Rapid testing crucial for all patients because finding a mutation significantly impacts this condition’s clinical management. We report rare case focal CHI after homozygous who underwent selective lesionectomy...
Abstract BACKGROUND Neonatal sepsis is the third most common cause of neonatal mortality. The incidence septic shock in low-income countries 26.8% with a mortality rate 35.4%. hemodynamic effects noradrenaline on pediatric population have been well documented, but studies neonates are sparse. This research was carried out to evaluate clinical and parameters shock. METHODS single-center prospective cohort study level III intensive care unit tertiary hospital. Neonates defined by Tollners...
Objectives: Primary objective was to determine the diagnostic accuracy of lung ultrasound score (LUS) in predicting need for surfactant therapy preterm neonates (< 34 weeks) with respiratory distress. Secondary objectives were correlate LUS corresponding oxygen saturation fraction inspired ratio (SpO2/FiO2), arterial/Alveolar pressure (a/A]and chest x-ray (CXR) findings. Working hypothesis: reflects aeration and will requirement It can be an accurate timely predictor therapy. Study...
Ensuring quality of care in Low and Middle Income countries (LMICs) is challenging. Despite the implementation various improvement (QI) initiatives public private sectors, sustenance improvements continues to be a major challenge. A team healthcare professionals India developed digital community practice (dCoP) focusing on QI which now has global footprints.The dCoP was conceptualised as multitiered structure operational online at www.nqocncop.org from August 2020 onwards. The platform hosts...
Of the various options available for imaging brain and other intracranial structures in neonates, ultrasound (US) finds an important place because of its ease use. Despite limited delineation structures, US scores over modalities such as computed tomography magnetic resonance due to lack radiation exposure relatively quick at bedside. A brief overview equipment steps doing a cranial ultrasonography is given here.
Global Nutrition Report (GNR), 2020 indicates, India made limited progress towards achieving exclusive breastfeed-ing targets (58.0%infant aged 0-5 months breastfed).India is 'on course' to meet the target for stunting with 34.7% of children under 5 years stunted (higher than average Asia region: 21.8%). 5There a need address these gaps.If addressed effectively and given that it "on course", can achieve being nation free at least one "nutrition burdens" i.e. "stunting". 6In this scenario,...