- Force Microscopy Techniques and Applications
- Conducting polymers and applications
- Analytical Chemistry and Sensors
- Electrochemical sensors and biosensors
- Mechanical and Optical Resonators
- Molecular Junctions and Nanostructures
- Advanced biosensing and bioanalysis techniques
- Polymer Surface Interaction Studies
- Multiple Sclerosis Research Studies
- Electrochemical Analysis and Applications
- Monoclonal and Polyclonal Antibodies Research
- Near-Field Optical Microscopy
- Advanced Sensor and Energy Harvesting Materials
- Nanocomposite Films for Food Packaging
- Pesticide and Herbicide Environmental Studies
- Advanced Cellulose Research Studies
- Immunotherapy and Immune Responses
- Integrated Circuits and Semiconductor Failure Analysis
- Natural Fiber Reinforced Composites
- Advanced MEMS and NEMS Technologies
- RNA Interference and Gene Delivery
- Soil Management and Crop Yield
- Advanced Biosensing Techniques and Applications
- RNA and protein synthesis mechanisms
- Anodic Oxide Films and Nanostructures
Universidade Federal de São Carlos
2013-2022
Universidade de Sorocaba
2009-2016
Universidade Unigranrio
2013
Universidade de São Paulo
2005-2012
Brazilian Agricultural Research Corporation
2005-2012
Hospital Universitário da Universidade de São Paulo
2008
University of Windsor
2006
The Langmuir–Freundlich model is used to explain the adsorption of p53 biomarker onto an immunosensor for early detection cancer.
This paper reports on the adsorption of an ultrathin chitosan layer spin-coated films cellulose, where efficient attachment was induced by oxidizing cellulose which provided anionic sites for electrostatic interaction with positively charged chitosan. Both oxidation and were confirmed Fourier transform infrared spectroscopy (FTIR) X-ray photoelectron (XPS) measurements. The molecular-level between involved NH groups, as inferred from disappearance caused amide band at 1667 cm−1 in FTIR...
A low-cost sensor array system for banana ripeness monitoring is presented. The sensors are constructed by employing a graphite line-patterning technique (LPT) to print interdigitated electrodes on tracing paper and then coating the printed area with thin film of polyaniline (PANI) in-situ polymerization as gas-sensitive layer. PANI layers were used detection volatile organic compounds (VOCs), including ethylene, emitted during ripening. influence various acid dopants, hydrochloric (HCl),...
The use of agrochemicals has increased considerably in recent years, and consequently, there been exposure ecosystems human populations to these highly toxic compounds. study development methodologies detect substances with greater sensitivity become extremely relevant. This article describes, for the first time, atomic force spectroscopy (AFS) detection enzyme-inhibiting herbicides. A nanobiosensor based on an microscopy (AFM) tip functionalised acetolactate synthase (ALS) enzyme was...
Paclitaxel (Taxol®), is a drug used to treat ovarian, breast, lung and bladder cancer. However, the low solubility of this in water major limitation its clinical use. One strategy overcome would be encapsulate paclitaxel polymeric microspheres that are biocompatible can as carriers. The aim study was use bioresorbable, copolymer poly-L-co-D,L-lactic acid (PLDLA) 70:30 rate produce characterize containing paclitaxel. simple emulsion technique obtain spherical were studied by scanning electron...
In this work, the synthetic hydroxyapatite (HAP) was studied using different preparation routes to decrease crystal size and study temperature effect on HAP nano-sized crystallization. X-ray diffraction (XRD) analysis indicated that all samples were composed by crystalline amorphous phases . The sample with greater quantity of phase (40% total mass) studied. powder heated at 300, 500, 700, 900 1150 °C. All characterized XRD their patterns refined Rietveld method. crystallites presented an...
Nanobiosensors can be built via functionalization of atomic force microscopy (AFM) tips with biomolecules capable interacting the analyte on a substrate, and detection being performed by measuring between immobilized biomolecule analyte. The optimization such sensors may require multiple experiments to determine suitable experimental conditions for immobilization detection. In this study we employ molecular modeling techniques assist in design nanobiosensors detect herbicides. As proof...
The herbicide residue from intensive agricultural activity provokes environmental disturbances and human health injuries. Among the enzymatic disruptor herbicides, mesotrione is able to inhibit 4-hydroxyphenylpyruvate dioxygenase (HPPD), which plays a key role in carotenoid synthesis. Therefore, enzyme-based sensors are innovative options for monitoring herbicides used agriculture. Compared standard sensors, biosensors have assorted advantages, such as practicality, quick response, low cost,...
The experimental use of poly (alcohol-vinyl) (PVA) as a skin curative is increasing widely. However, the this hydrogel challenging due to its favorable properties for microbiota growth. association with silver nanoparticles (AgNPs) an antimicrobial agent turns match PVA dressing, it focuses on creating physical barrier avoid wound dehydration. When associated extracellular components, such collagen matrix, device obtained can create desired biological conditions act substitute. This study...
Atomic force spectroscopy, a technique derived from Force Microscopy (AFM), allowed us to distinguish nonspecific and specific interactions between the acetolactate synthase enzyme (ALS) anti-atrazine antibody biomolecules herbicides imazaquin, metsulfuron-methyl atrazine. The presence of increased adhesion (Fadh) AFM tip herbicides, which made modified powerful biosensor. Increases approximately 132% 145% in Fadh values were observed when functionalized with ALS was used detect imazaquin...
This paper describes a silicon cantilever sensor coated with conducting polymer layer. The mechanical response (deflection) of the bimaterial (the microcantilever) was investigated under influence several volatile compounds-methanol, ethanol, acetone, propanol, dichloroethane, toluene and benzene. variations in deflection uncoated microcantilevers when exposed to organic compounds were evaluated, results indicated that highest sensitivity obtained microcantilever methanol. not sensitive...
Nanoporous anodic alumina (NAA), obtained via aluminum anodization, have been used as template for fabrication of nanostructure materials and photonic devices. In order to promote the formation regular porous control desired properties, high-purity pretreatment Al surfaces are mandatory. This procedure consists in electrochemically removing external irregular layer metal promoting a flat, bright smooth metallic surface. this study, effect electropolishing parameters on commercial samples...
The aim of this study was to develop a cantilever nanobiosensor for atrazine detection in liquid medium by immobilising the biological recognition element (tyrosinase vegetal extract) on its surface with self-assembled monolayers using gold, 16-mercaptohexadecanoic acid, 1-ethyl-3-[3-dimethylaminopropyl] carbodiimide hydrochloride/n-hydroxysuccinimide. Cantilever nanobiosensors presented compression tension increase when concentrations were increased, limit and quantification 7.754 ppb...