Xia Chen

ORCID: 0000-0001-9626-2352
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About
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Research Areas
  • Reconstructive Facial Surgery Techniques
  • Ear Surgery and Otitis Media
  • Reconstructive Surgery and Microvascular Techniques
  • Plant Molecular Biology Research
  • Plant Stress Responses and Tolerance
  • Oral and Maxillofacial Pathology
  • MicroRNA in disease regulation
  • Periodontal Regeneration and Treatments
  • Cancer-related molecular mechanisms research
  • Lipid metabolism and disorders
  • Ginseng Biological Effects and Applications
  • Pasture and Agricultural Systems
  • Mesenchymal stem cell research
  • Cognitive Science and Education Research
  • Neurological Disorders and Treatments
  • Vehicle emissions and performance
  • Genetic Mapping and Diversity in Plants and Animals
  • S100 Proteins and Annexins
  • Nasal Surgery and Airway Studies
  • Environmental and Agricultural Sciences
  • Genetics, Aging, and Longevity in Model Organisms
  • Photosynthetic Processes and Mechanisms
  • Genetic and phenotypic traits in livestock
  • Pharmacological Effects of Natural Compounds
  • Medicinal Plants and Neuroprotection

Yunnan Provincial Hospital of Traditional Chinese Medicine
2025

Shanghai Ninth People's Hospital
2018-2022

Shanghai Jiao Tong University
2015-2022

Daping Hospital
2019

Army Medical University
2019

Tobacco Research Institute
2017-2018

China Tobacco
2017-2018

Second Xiangya Hospital of Central South University
2017

Central South University
2017

Nanfang Hospital
2013

The therapeutic method traditionally used in bone defect reconstruction is autologous grafting. most common problems affecting this type of repair approach are absorption and donor trauma. taken study overcomes these problems. Bone marrow stromal cells (BMSCs) provided the crucial seed cells. Fibrin biological scaffolds were formed by combining BMSCs with concentrated growth factor (CGF). isolated from Wistar rat femurs; CGF was prepared heart blood. Five groups created for comparative...

10.1038/s41598-018-24364-5 article EN cc-by Scientific Reports 2018-04-11

The plant-specific PIN-FORMED (PIN) auxin efflux proteins have been well characterized in many plant species, where they are crucial the regulation of transport various aspects development. However, little is known about exact roles PIN genes during development Nicotiana species. This study investigated tobacco (Nicotiana tabacum) and two ancestral species sylvestris tomentosiformis). Genome-wide analysis N. tabacum genome identified 20 family. An in-depth phylogenetic tabacum,...

10.1111/ppl.12547 article EN Physiologia Plantarum 2017-01-27

Abstract Background This study investigated the impacts and mechanisms of yunweiling in management Functional Constipation (FC) using network pharmacology experimental research. Methods Using Traditional Chinese Medicine Systems Pharmacology Database Analysis Platform (TCMSP), Genecard, Online Mendelian Inheritance Man (OMIM) databases, a potential gene target for treating FC was found. A pharmacological built viewed Cytoscape. protein interaction map created with STRING ‘clusterProfiler’...

10.1002/ame2.12567 article EN cc-by-nc-nd Animal Models and Experimental Medicine 2025-02-10

Abstract Objective To explore the effectiveness of insulin‐like growth factor 1 receptor (IGF‐1R)/PI3K/AKT pathway in promoting synthesis auricular chondrocyte extracellular matrix (ECM) using concentrated (CGF). Methods Chondrocytes isolated from remnant cartilage microtia patients were randomly divided into different experimental and control groups, then stimulated with a reagent. IGF‐1 released by CGF was quantified enzyme‐linked immunosorbent assay. Glycosaminoglycan (GAG), proteoglycan,...

10.1002/jcp.27316 article EN Journal of Cellular Physiology 2018-11-23

Advanced osteosarcoma (OS) is usually treated by preoperative and postoperative chemotherapy, but there are a very limited number of active agents. Celecoxib (Cel) COX-2-selective nonsteroidal anti-inflammatory drug its antitumoral effect has been shown widely in variety cancers including OS cells vitro. However, the potential combinational Cel with other biological therapy not reported cells. In this study, effects Cel, miR-34a mimics, their combination on cell proliferation (MTT assay),...

10.1097/cad.0000000000000530 article EN Anti-Cancer Drugs 2017-06-23

Background Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. Various treatment regimens and combinations therapies provide only partial renoprotection. Therefore new approaches are needed to retard progression DN. The aim present study was evaluate role a novel spiroalkaloid from Acorus tatarinowii named acortatarin A (AcorA) in inhibiting high glucose-induced extracellular matrix accumulation mesangial cells (MCs). Methods cytotoxity AcorA on MCs examined by...

10.3760/cma.j.issn.0366-6999.20122445 article EN cc-by-nc-nd Chinese Medical Journal 2013-04-05

This study was conducted to investigate the differentially expressed profiles of long non-coding RNAs (lncRNAs) in HBV-associated HCC (HBV-HCC), which may serve as potential diagnostic biomarkers and therapeutic targets. To examine lncRNAs mRNAs using microarray analysis, we collected 15 specimens: five tissues, paired adjacent peritumoral liver tissues (APLT), distant (DPLT). Then, Gene Ontology (GO) Kyoto Encyclopedia Genes Genomes (KEGG) analyses were performed predict biological roles...

10.2147/ott.s230377 article EN OncoTargets and Therapy 2019-11-01

The concept of unconscious emotion has developed from addressing subliminal emotional stimulus to emphasizing unawareness experience. To integrate the two different paths explore emotion, Wiens model, an information-processing model was introduced. According there exist parallel approaches understand which are stimulus-focused approach and experience-focused approach. core ideas, empirical studies, theoretical debates, methodological challenges essences along separate ways were then...

10.3724/sp.j.1042.2015.01701 article EN Advances in Psychological Science 2015-01-01

Significant improvements have been achieved in microtia reconstruction using an autogenous costal cartilage framework. However, complications such as skin necrosis and exposure often destroy the final contour of reconstructed auricle. Local fascia flaps are commonly used salvage surgery because their reliability satisfactory results. Here, we report case a 26-year-old woman with multiple necroses on day 21 after first-stage reconstruction. The area was covered by temporoparietal flap...

10.1016/s2096-6911(21)00085-6 article EN cc-by Chinese Journal of Plastic and Reconstructive Surgery 2021-06-01
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