Zhenlong Zhao

ORCID: 0000-0001-9640-8921
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About
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Research Areas
  • Thyroid and Parathyroid Surgery
  • Thyroid Cancer Diagnosis and Treatment
  • Rock Mechanics and Modeling
  • Head and Neck Anomalies
  • Parathyroid Disorders and Treatments
  • Geomechanics and Mining Engineering
  • Landslides and related hazards
  • Geophysical Methods and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Tunneling and Rock Mechanics
  • Bone health and treatments
  • Grouting, Rheology, and Soil Mechanics
  • Geotechnical Engineering and Underground Structures
  • Thyroid Disorders and Treatments
  • Concrete and Cement Materials Research
  • Geoscience and Mining Technology
  • Vitamin D Research Studies
  • Neuroendocrine Tumor Research Advances
  • Drilling and Well Engineering
  • Vibration and Dynamic Analysis
  • Smart Materials for Construction
  • Ultrasound and Hyperthermia Applications
  • Liver Disease and Transplantation
  • Innovative concrete reinforcement materials
  • Advanced Combustion Engine Technologies

China-Japan Friendship Hospital
2019-2025

State Key Laboratory of Engine and Powertrain System
2024

Linyi University
2023

Qiqihar University
2017-2023

China University of Mining and Technology
2019-2022

Xi'an University of Technology
2021

Weichai Power (China)
2021

Shandong University of Science and Technology
2017

Jilin University
2016

Jilin Province Science and Technology Department
2016

Background Microwave ablation (MWA) and radiofrequency (RFA) have recently attracted interest as minimally invasive treatment modalities for papillary thyroid carcinoma (PTC). However, the outcomes of T1N0M0 PTC are not well characterized. Purpose To evaluate efficacy safety thermal (MWA or RFA) solitary in patients who were ineligible (due to presence comorbid cardiovascular disease, renal failure, other malignancy, etc) refused surgery. Materials Methods This was a retrospective...

10.1148/radiol.2021202735 article EN Radiology 2021-04-27

Background Microwave ablation (MWA) has attracted interest as a minimally invasive treatment for papillary thyroid carcinoma (PTC). However, comparisons between MWA and surgical resection (SR) in the management of T1N0M0 PTC are rare. Purpose To compare technical effectiveness, disease progression, complications SR solitary PTC. Materials Methods This retrospective study was conducted single center. A total 1029 patients with treated either or from January 2015 to May 2021 were studied...

10.1148/radiol.212313 article EN Radiology 2022-05-10

Background Microwave ablation (MWA) is currently under preliminary investigation for the treatment of multifocal papillary thyroid carcinoma (PTC) and has shown promising efficacy. Compared with surgical resection (SR), MWA minimally invasive could preserve function. However, a comparative analysis between SR warranted to draw definitive conclusions. Purpose To compare preoperative US-detected T1N0M0 PTC in terms overall 1-, 3-, 5-year progression-free survival rates complication rates....

10.1148/radiol.230459 article EN Radiology 2024-04-01

Ultrasound (US)-guided thermal ablation has generated recent interest as minimally invasive treatments of primary hyperparathyroidism (pHPT). But definitive evidence for the efficacy in treating pHPT is not well characterized.This work aims to evaluate effectiveness and safety pHPT.From January 2015 March 2020, data pertaining patients who received at 4 centers were retrospectively analyzed. The median follow-up duration was 18.1 months (interquartile range, 6.5-42.2 months). A cure referred...

10.1210/clinem/dgab240 article EN cc-by-nc-nd The Journal of Clinical Endocrinology & Metabolism 2021-04-13

Ultrasound-guided thermal ablation plays an important role in the management of thyroid disease. The objective this study was to evaluate feasibility, efficacy, and safety for patients with solitary T1bN0M0 papillary carcinoma (PTC) who are ineligible or unwilling undergo surgery.Data pertaining 172 (38 males 134 females) received therapy at 12 hospitals between April 2015 March 2020 were retrospectively analyzed. mean duration follow-up 24.9 ± 14.1 months (range, 12-60). technical success,...

10.1210/clinem/dgaa776 article EN The Journal of Clinical Endocrinology & Metabolism 2020-10-27

Purpose Ultrasound-guided thermal ablation (including microwave [MWA] and radiofrequency [RFA]) has emerged as a remarkable technology for the treatment of benign malignant diseases. The objective this multicenter study was to assess efficacy safety in large cohort patients with papillary thyroid microcarcinoma (PTMC).Materials methods Retrospective 725 who underwent MWA/RFA at 11 centers between March 2015 2020. mean age 46 ± years (range, 22–81); follow-up time 21 13 months 6–60). Changes...

10.1080/02656736.2021.1936218 article EN cc-by International Journal of Hyperthermia 2021-01-01

Abstract Context Recurrent laryngeal nerve (RLN) injury is a complication of thermal thyroid nodule treatment. Objective We investigated the influencing factors RLN in patients who underwent ablation nodules. Methods The data 1004 (252 male, 752 female; median age 44 years) were retrospectively reviewed. Patients divided into benign cystic, solid, and papillary cancer (PTC) groups. parameters related to analyzed, including largest diameter, location nodules, shortest distance capsule...

10.1210/clinem/dgac177 article EN The Journal of Clinical Endocrinology & Metabolism 2022-03-21

Thyroid nodule rupture (TNR) is a rare and severe complication after thermal ablation (TA), mostly from benign thyroid nodules (BTN).

10.1080/02656736.2024.2439536 article EN cc-by International Journal of Hyperthermia 2025-01-05

This study aims to examine the ultrasonic characteristics of perithyroid fascial spaces following in vivo hydrodissection, validating their visualization through a comparative analysis with anatomical references. A retrospective review was conducted on data from 2390 patients (631 males and 1759 females, median age 46 years, 25–75% interquartile range 26–69 years) who underwent microwave ablation for thyroid tumors, including 1436 benign nodules 954 papillary carcinomas. Detailed...

10.1038/s41598-025-88306-8 article EN cc-by-nc-nd Scientific Reports 2025-02-06

To evaluate the feasibility, safety and efficiency of microwave ablation (MWA) T1N0M0 papillary thyroid carcinoma (PTC) locating in dangerous region. This is a clinical retrospective study, data patients who underwent thermal for PTC from June 2016 to March 2021 were reviewed. After ablation, rates technical success, as well changes tumor size volume, disappearance, disease progression, complications, assessed. According size, divided into T1a T1b subgroups. There was total 94 cases enrolled...

10.1186/s12885-025-13629-8 article EN cc-by-nc-nd BMC Cancer 2025-02-11

Objective The present study aimed to analyze the relationship between incidence of complications and tumor size following thermal ablation benign thyroid nodules (BTNs).

10.1080/02656736.2025.2464205 article EN cc-by International Journal of Hyperthermia 2025-02-13

To evaluate the efficacy and safety of thermal ablation (TA) for follicular thyroid neoplasms (FTN) ≤ 3 cm. This retrospective multicenter study enrolled 161 patients (131 females; mean age, 46 ± 15 years [range, 11-86]) who underwent TA FTN cm between January 2014 October 2023 from eight centers in China. The median follow-up time was 12 months (IQR, 12-24 months). Based on maximum diameter (MD) nodule, were divided into two groups: Group 1 (MD 2 cm) (2 < MD cm). Post-ablation assessments...

10.1007/s12672-025-01984-8 article EN cc-by-nc-nd Discover Oncology 2025-02-20

To evaluate changes in thyroid function post-thermal ablation (TA) of nodules and to identify risk factors associated with post-ablation abnormalities. A retrospective analysis 2,264 cases treated TA between June 2015 July 2024 was conducted, including 1,169 benign (BTNs) 1,095 papillary carcinoma (PTC) cases. Thyrotropin (TSH), free triiodothyronine (FT3), thyroxine (FT4) levels were measured before treatment at 1, 3, 6, 9, 12 months post-ablation. FT3 remained significantly reduced (3.04 ±...

10.3389/fendo.2025.1557725 article EN cc-by Frontiers in Endocrinology 2025-02-27

Laboratory tests and numerical simulation are conducted to study mechanical behavior of rock containing two pre-existing holes in this paper. First all, rock-like specimens were prepared investigate acoustic emission characteristics the uniaxial compression. Different geometries obtained by changing angle center line with respect direction axial loading. Experimental results show that stress-strain curves present obvious fluctuation, evolution process signal can be divided into four stages....

10.1080/19648189.2019.1657961 article EN European Journal of Environmental and Civil engineering 2019-09-02

Objective: To evaluate the safety, feasibility, and efficacy of microwave ablation (MWA) for treatment primary hyperparathyroidism (PHPT). Materials Methods:This study enrolled 67 PHPT patients (22 men, 45 women; mean age, 56.0 ± 16.3 years; range, 18-83 years) from January 2015 to December 2018.The laboratory data, including serum intact parathyroid hormone (iPTH), calcium, phosphorus, alkaline phosphatase (ALP) levels, were evaluated before MWA again 2 hours, 1 day, 7 days, month, 3...

10.3348/kjr.2019.0593 article EN Korean Journal of Radiology 2020-01-01

<h2>Abstract</h2> The aim of this prospective study was to evaluate the value combination lymphatic contrast-enhanced ultrasound (LCEUS) and intravenous (IVCEUS) for identification cervical lymph node metastasis (CLNM) from papillary thyroid carcinoma (PTC). From November 2018 March 2019, 24 consecutive patients with PTC were evaluated. All underwent routine US, LCEUS IVCEUS. Pathology used as gold standard. After injection a contrast agent into parenchyma, vessels nodes (LNs) could be...

10.1016/j.ultrasmedbio.2020.10.003 article EN cc-by-nc-nd Ultrasound in Medicine & Biology 2020-11-04

Background To evaluate the feasibility, efficiency, and safety of microwave ablation (MWA) for papillary thyroid carcinoma (PTC) close to capsule.Methods The data 106 cases who underwent thermal from June 2014 September 2020 were retrospectively analyzed. mean follow-up time was 25 ± 11 months (range, 9–48 months). strategy fluid isolation successfully applied in all cases, PTC nodules extended ablation. technical success rate, Changes tumor size at different points after MWA...

10.1080/02656736.2021.1962549 article EN cc-by International Journal of Hyperthermia 2021-01-01
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