A5029822974- Microbial Natural Products and Biosynthesis
- Plant Pathogens and Fungal Diseases
- Fungal Biology and Applications
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Plant and fungal interactions
- Phytochemistry and Biological Activities
- Chemical synthesis and alkaloids
- Mycorrhizal Fungi and Plant Interactions
- Allelopathy and phytotoxic interactions
- Natural product bioactivities and synthesis
- Plant biochemistry and biosynthesis
- Plant-Microbe Interactions and Immunity
- Traditional Chinese Medicine Analysis
- Essential Oils and Antimicrobial Activity
- Nematode management and characterization studies
- Enzyme Production and Characterization
- Cancer Treatment and Pharmacology
- Drug-Induced Hepatotoxicity and Protection
- Weed Control and Herbicide Applications
- Plant Parasitism and Resistance
- Marine Sponges and Natural Products
- Pharmacological Effects of Natural Compounds
- Microbial Metabolites in Food Biotechnology
- Organic Chemistry Synthesis Methods
Universidad Nacional Autónoma de México
2016-2025
Instituto de Ecología
2005-2016
Cornell University
2016
University of Georgia
2016
Drew University
2015
University of Lausanne
2015
Centre Hospitalier Universitaire d'Angers
2015
Université Nantes Angers Le Mans
2015
Université d'Angers
2015
GTx (United States)
2015
To evaluate the phytotoxic, antifungal and antioomycete activity; and, determine chemical composition of volatile organic compounds (VOCs) semi-volatile metabolites produced by endophyte Hypoxylon anthochroum strain Blaci isolated from Bursera lancifolia.Based on its macro- micro-morphological features, was identified as Nodulisporium sp.; partial analysis ITS1-5.8-ITS2 ribosomal gene sequence revealed identity teleomorphic stage fungus H. anthochroum. Phytotoxic antimicrobial activities...
To determine the antifungal, anti‐oomycete and phytotoxic activity; chemical composition of volatile organic compounds (VOCs) produced by endophytic fungus Xylaria sp. PB3f3 isolated from Haematoxylon brasiletto Karst. Bioactivity VOCs were established using simple multiple antagonism bioassays, gas chromatography/mass spectrometry, respectively. The results showed that inhibited growth oomycetes Pythium aphanidermatum (78·3%), Phytophthora capsici (48·3%), fungi Alternaria solani (24·5%)...
From the fermentation mycelium of endophytic fungus Edenia gomezpompae were obtained several phytotoxic compounds including two new members naphthoquinone spiroketal family, namely, palmarumycin EG1 (1) and preussomerin EG4 (4). In addition, preussomerins EG1–EG3 (7–9) palmarumycins CP19 (2), CP17 (3), CP2 (6), as well ergosta-4,6,8(14),22-tetraen-3-one (5), obtained. Compounds 2, 3, 5 are to this species. The structures (2) (3) unambiguously determined by X-ray analysis. isolates organic...
During a study on the fungal endophytic associations with some trees of secondary forest El Eden Ecological Reserve located in northeastern Yucatan Peninsula Mexico, new species was isolated as an endophyte tree named chakah, chachah, or hukup (Bursera simaruba) by indigenous Mayas. This fungus is characterized producing strong musty odor and absence reproductive structures. Cultures this PDA form whitish, flocculose colony uncolored reverse mycelium that grows slowly. Scanning electron...
Plants express chitinase and chitinase-like proteins (CLPs) belonging to the glycosyl hydrolases of GH18 GH19 families, which exhibit varied functions. CLPs in family have been structurally functionally characterized; however, there are no structures available for any member family. In this study, two from rubber tree Hevea brasiliensis (HbCLP1 HbCLP2) were cloned, expressed characterized. HbCLP1 was identical allergen Hev b 11.0101 previously described by others, while HbCLP2 a novel...
Abstract Bioactivity‐directed fractionation of the organic mycelium extract endophytic fungus Acremonium camptosporum W. Gams (Clavicipitaceae), isolated from leaves Bursera simaruba (Burseraceae), led to isolation six major heterodimeric polyketides, including one not previously characterized acremoxanthone derivative. In addition, already known C, acremonidins A and B, acremoxanthones B were obtained. The structure new compound was established by extensive NMR studies, DEPT, COSY, NOESY,...
During a search for new α-glucosidase and protein tyrosine phosphatase 1B inhibitors from fungal sources, eight secondary metabolites, including two anthranilic acid-derived peptides (1 2), four glycosylated anthraquinones (3–6), 4-isoprenylravenelin (7), dimer of 5,8-dihydroxy-4-methoxy-α-tetralone (8), along with known compounds (9–12), were isolated solid rice-based cultures Malbranchea circinata. The structural elucidation these metabolites was performed using 1D 2D NMR techniques...
Bioactivity-directed fractionation of the combined culture medium and mycelium extract endophytic fungus Xylaria feejeensis strain SM3e-1b, isolated from Sapium macrocarpum, led to isolation three known natural products: (4S,5S,6S)-4-hydroxy-3-methoxy-5-methyl-5,6-epoxycyclohex-2-enone or coriloxine, 1; 2-hydroxy-5-methoxy-3-methylcyclohexa-2,5-diene-1,4-dione, 2; 2,6-dihydroxy-5-methoxy-3-methylcyclohexa-2,5-diene-1,4-dione fumiquinone B, 3. This is first report compound 3 being this...
Endophytic fungi are microorganisms that live inside plant tissues without causing disease symptoms. In most cases, their relationship with the host is considered beneficial because endophyte able to produce bioactive metabolites can use as defense mechanisms, and this allows survival of both organisms. Recent studies have demonstrated endophytic fungus confers protection against attack by pathogens herbivores. Since they ability benefit plant, it reasonable think diverse compounds produced...
Previously non-isolated compounds (scopoletin and β-D-Glucopyranoside, (1R)-O-isopropyl 6-O-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)-2,3,4-triacetate) were isolated from an organic extract of the Cnidoscolus chayamansa stem. Also, lupeol acetate (main compound, 49.7 mg/g dry extract) scopoletin (0.19 quantified by HPLC analysis this extract. The protective activity C. against hepatotoxicity induced antitubercular drugs [Rifampicin (50 mg/kg), Isoniazid Pyrazinamide (100 mg/kg)] are reported....
Previous report described that CHCl3:MeOH extract of C. chayamansa leaves and pure compounds (moretenol, moretenyl acetate, kaempferol-3,7-dimethyl ether, 5-hydroxy-7-3',4'-trimethoxyflavanone) showed important topical systemic anti-inflammatory activity in acute model, as well vitro antimycobacterial antiprotozoal activities. In this paper, we describe the vivo hepatoprotective effects chronic model isolation additional (moretenone lupeol acetate). The was determined at 39 days using Balb/c...